Alpha granules, (α-granules) also known as platelet alpha-granules are a cellular component of platelets. Platelets contain different types of granules...
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are found only in platelets and are smaller than alpha granules. The origin of these dense granules is still unknown, however, it is thought that may...
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platelet alpha-granule deficiency, is a rare congenital autosomal recessive bleeding disorder caused by a reduction or absence of alpha-granules in blood...
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Examples of granules include granulocytes, platelet granules, insulin granules, germane granules, starch granules, and stress granules. A group of leukocytes...
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Alpha-synuclein (aSyn) is a protein that, in humans, is encoded by the SNCA gene. Alpha-synuclein is a neuronal protein that regulates synaptic vesicle...
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Weibel–Palade body (redirect from Palade granule)
physiology is the alpha-granule of platelets, which also contains vWF. Weibel–Palade bodies are the main source of vWF, while α-granules probably play a...
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ultra-large VWF in endothelium (in the Weibel–Palade bodies), megakaryocytes (α-granules of platelets), and subendothelial connective tissue. The basic VWF monomer...
17 KB (2,121 words) - 05:51, 4 December 2024
α2-Macroglobulin (α2M) or alpha-2-macroglobulin is a large (720 KDa) plasma protein found in the blood. It is mainly produced by the liver, and also locally...
14 KB (1,631 words) - 23:13, 9 November 2024
Alpha-1 antitrypsin or α1-antitrypsin (A1AT, α1AT, A1A, or AAT) is a protein belonging to the serpin superfamily. It is encoded in humans by the SERPINA1...
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PRF release several biologically active proteins including; platelet alpha granules, platelet‑derived growth factor (PDGF), transforming growth factors‑β...
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deficient granules in platelets. Individuals with these disorders have too few or abnormally functioning alpha granules, delta granules, or both alpha and delta...
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chemokine (C-X-C motif) ligand 4 (CXCL4) . This chemokine is released from alpha-granules of activated platelets during platelet aggregation, and promotes blood...
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binding protein binding copper ion binding Cellular component platelet alpha granule extracellular vesicle endoplasmic reticulum lumen membrane plasma membrane...
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Platelet (section Granule secretion)
to maintain a discoid shape Organelle zone — rich in platelet granules. Alpha granules contain clotting mediators such as factor V, factor VIII, fibrinogen...
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Alpha 2-antiplasmin (or α2-antiplasmin or plasmin inhibitor) is a serine protease inhibitor (serpin) responsible for inactivating plasmin. Plasmin is...
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granules called Weibel-Palade bodies. In unactivated platelets P-selectin is stored in α-granules. Other names for P-selectin include CD62P, Granule Membrane...
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Eosinophil (redirect from Eosinophil granule proteins)
eosinophilic or "acid-loving" due to their large acidophilic cytoplasmic granules, which show their affinity for acids by their affinity to coal tar dyes:...
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Fijalkowska I, Walkowiak B, Cierniewski CS (September 2001). "Acute phase protein alpha 1-acid glycoprotein interacts with plasminogen activator inhibitor type...
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In the cellular biology, stress granules are biomolecular condensates in the cytosol composed of proteins and RNA that assemble into 0.1–2 μm membraneless...
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small GTPases is a signal transduction pathway that triggers platelet alpha-granule release". Cell. 115 (7): 851–862. doi:10.1016/S0092-8674(03)01014-6...
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defect in the secretion of the granule contents in neutrophils. There are other causes for a congenital platelet alpha-granule-deficient bleeding disorder...
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the dense granules and alpha granules. From the dense granules, serotonin and adenosine diphosphate are released. From the alpha granules come molecules...
9 KB (1,278 words) - 22:10, 30 October 2023
endoplasmic reticulum-Golgi intermediate compartment membrane platelet alpha granule lumen Golgi membrane extracellular space Biological process hemostasis...
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low-molecular-weight kininogen. Plasmin has been shown to interact with Thrombospondin 1, Alpha 2-antiplasmin and IGFBP3. Moreover, plasmin induces the generation of bradykinin...
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Alpha-1-B glycoprotein is a 54.3 kDa protein in humans that is encoded by the A1BG gene. The protein encoded by this gene is a plasma glycoprotein of...
15 KB (1,379 words) - 02:50, 29 November 2023
KL, Marshall-Carlson L, Bainton DF (July 1989). "GMP-140, a platelet alpha-granule membrane protein, is also synthesized by vascular endothelial cells...
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chain has been shown to interact with Lipoprotein(a). Fibrin Fibrinogen alpha chain Fibrinogen gamma chain GRCh38: Ensembl release 89: ENSG00000171564...
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Alpha 1-antichymotrypsin (symbol α1AC, A1AC, or a1ACT) is an alpha globulin glycoprotein that is a member of the serpin superfamily. In humans, it is encoded...
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functional heterodimers. Though PDGF is synthesized, stored (in the alpha granules of platelets), and released by platelets upon activation, it is also...
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NDP-glucose—starch glucosyltransferase (redirect from Granule bound starch synthase)
enzyme class is NDP-glucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase. Other names in common use include granule-bound starch synthase, starch synthase...
3 KB (327 words) - 18:17, 23 January 2024