aminoacyl-tRNA synthetase (aaRS or ARS), also called tRNA-ligase, is an enzyme that attaches the appropriate amino acid onto its corresponding tRNA....
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Aminoacyl-tRNA (also aa-tRNA or charged tRNA) is tRNA to which its cognate amino acid is chemically bonded (charged). The aa-tRNA, along with particular...
13 KB (1,630 words) - 22:05, 10 May 2024
The aminoacyl-tRNA synthetases catalyse the attachment of an amino acid to its cognate transfer RNA molecule in a highly specific two-step reaction. These...
5 KB (585 words) - 15:20, 1 October 2024
covalent attachment to the tRNA 3' end is catalysed by enzymes called aminoacyl tRNA synthetases. During protein synthesis, tRNAs with attached amino acids...
67 KB (8,010 words) - 00:05, 30 November 2024
Aminoacyl-tRNA synthetases, class II is a family of proteins. These proteins catalyse the attachment of an amino acid to its cognate transfer RNA molecule...
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enzyme aminoacyl tRNA synthetase catalyzes the binding of adenosine triphosphate (ATP) to a corresponding amino acid, forming a reactive aminoacyl adenylate...
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and such reactions are often catalyzed by a specific enzymes, aminoacyl tRNA synthetase. For example, if the amino acid that attach to the end is phenylalanine...
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Wobble base pair (section tRNA base pairing schemes)
seen on aminoacyl tRNA synthetase and the genomes of E. coli tRNA at the External links, Information on Aminoacyl tRNA Synthetases and Genomic tRNA Database...
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Expanded genetic code (section tRNA/synthetase pair)
tRNA and aminoacyl tRNA synthetase are required, these are called the orthogonal set. The orthogonal set must not crosstalk with the endogenous tRNA and...
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Antisynthetase syndrome (redirect from Anti-synthetase syndrome)
radiologic features, clinical criteria, and identification of aminoacyl tRNA synthetase antibodies. Immunosuppressive medications such as mycophenolate...
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cognate tRNA. This enzyme participates in glutamate metabolism and aminoacyl-trna biosynthesis. The human gene for glutaminyl-tRNA synthetase is QARS...
8 KB (775 words) - 02:36, 16 September 2024
aminoacyl tRNA synthetases, enzymes that catalyze the esterification of specific amino acids or their precursors to their corresponding cognate tRNAs...
22 KB (2,169 words) - 18:47, 5 December 2024
RARS (gene) (redirect from Arginyl-tRNA synthetase)
Arginyl-tRNA synthetase, cytoplasmic is an enzyme that in humans is encoded by the RARS gene. Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by...
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creating a unique codon (recoding) and a corresponding transfer-RNA:aminoacyl – tRNA-synthetase pair to encode it with diverse physicochemical and biological...
73 KB (8,046 words) - 18:12, 31 December 2024
carbon-oxygen bonds in tRNA and related compounds. More specifically, it belongs to the family of the aminoacyl-tRNA synthetases. These latter enzymes...
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Translation (biology) (redirect from RNA translation)
where mRNA codons are matched through complementary base pairing to specific tRNA anticodons. Aminoacyl-tRNA synthetases that mispair tRNAs with the...
35 KB (4,027 words) - 10:30, 24 December 2024
in glycine, serine and threonine metabolism and aminoacyl-trna biosynthesis. Glycyl-tRNA synthetase has been shown to interact with EEF1D. Mutant forms...
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WARS (gene) (redirect from Tryptophanyl-tRNA synthetase, cytoplasmic)
Tryptophanyl-tRNA synthetase, cytoplasmic is an aminoacyl-tRNA synthetase enzyme that attaches the amino acid tryptophan to its cognate tRNA. In humans...
9 KB (1,042 words) - 01:52, 4 March 2023
member of the class I aminoacyl-tRNA synthetase family. The encoded enzyme catalyzes the ATP-dependent ligation of L-leucine to tRNA(Leu). It is found in...
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2005, aTyr was founded by Paul Schimmel, and Xiang-Lei Yang, two aminoacyl tRNA synthetase scientists at The Scripps Research Institute. In 2009, Bruce Beutler...
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transfer RNA (tRNA) with a CUA anticodon, and the pylS gene, which encodes a class II aminoacyl-tRNA synthetase that charges the pylT-derived tRNA with pyrrolysine...
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is catalyzed by aminoacyl-tRNA synthetase, and requires a molecule of ATP. The amino acid bound to the tRNA is called an aminoacyl-tRNA, and is considered...
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glycyl-tRNA synthetase (GlyRS). Glycyl-tRNA synthetase is a class II aminoacyl-tRNA synthetase and acts as the catalyst for the synthesis of glycyl-tRNA by...
42 KB (4,626 words) - 15:43, 7 December 2024
transfer RNA molecule, which carries the amino acid corresponding to the codon it recognizes. The enzyme aminoacyl tRNA synthetase "charges" the tRNA molecules...
103 KB (10,813 words) - 10:10, 30 December 2024
Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 is a protein that in humans is encoded by the AIMP1 gene. The protein encoded...
9 KB (1,143 words) - 01:45, 24 December 2023
Alanyl—tRNA synthetase 1 (AARS1) is an enzyme that is encoded by the AARS1 gene in humans and is a member of the aminoacyl-tRNA synthetases (ARSs) family...
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Aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 is an enzyme that in humans is encoded by the AIMP2 gene. The JTV1 gene is located...
8 KB (945 words) - 19:47, 3 March 2023
This gene encodes a highly conserved enzyme that belongs to the aminoacyl-tRNA synthetase class IIc subfamily. This enzyme comprises the regulatory beta...
6 KB (748 words) - 21:03, 3 March 2023
Methionyl-tRNA synthetase, cytoplasmic is an enzyme that in humans is encoded by the MARS gene. Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs...
6 KB (731 words) - 04:11, 14 October 2022
D arm (category RNA)
it acts as a recognition site for aminoacyl-tRNA synthetase, an enzyme involved in the aminoacylation of the tRNA molecule. The D stem is also believed...
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