Anti-histone antibodies are autoantibodies that are a subset of the anti-nuclear antibody family, which specifically target histone protein subunits or...

as anti-Ro antibodies, anti-La antibodies, anti-Sm antibodies, anti-nRNP antibodies, anti-Scl-70 antibodies, anti-dsDNA antibodies, anti-histone antibodies...

lungs. Anti-histone antibodies in 95% of cases among those taking procainamide, hydralazine, chlorpromazine, and quinidine; however, these antibodies have...

SS-A/Ro Antibodies, IgG, Serum". www.mayocliniclabs.com. Mayo Clinic Laboratories. Retrieved 2 July 2020. "SSB – Clinical: SS-B/La Antibodies, IgG, Serum"...

centromere B and histone. Serum is incubated with the beads and in the presence of anti-dsDNA antibodies, or any other ANA, the antibodies will bind and...

diseases (notably lupus erythematosus) are associated with such antibodies. Antibodies are produced by B cells in two ways: (i) randomly, and (ii) in response...

Other mechanisms that may be used[citation needed] are tests for Anti-histone antibodies, Chromatin and vitamin D, and chest X-ray to show signs of pericardial...

antinuclear antibodies include anti-Smith and anti-double stranded DNA (anti-dsDNA) antibodies (which are linked to SLE) and anti-histone antibodies (which...

wheat related disorders for 10 anti-ENA antibodies. SSA (Ro) SSB (La) RNP/Sm Jo-1 Sm Scl-70 Chromatin Centromere Histone RNA polymerase III 73% of celiac...

anti-RNP antibodies are closely related to Sjögren's syndrome: SS-A (Ro) and SS-B (La). Autoantibodies against snRNP are called Anti-Smith antibodies...

infectious disease than men. Women have a greater number of circulating antibodies than do men, which has implications for their development of autoimmune...

stabilizers and monoclonal antibodies. Global Initiative of Asthma (GINA) is the official guideline on the usage of anti-asthmatic agents. The GINA guideline...

Nomenclature of monoclonal antibodies. The abbreviations in the column Type are as follows: mab: whole monoclonal antibody Fab: fragment, antigen-binding...

acidosis. Among the complications discussed above, women with anti-Ro/SS-A and anti-La/SS-B antibodies who become pregnant have an increased rate of neonatal...

deimination within rheumatoid joints. Test for presence of anti-citrullinated protein (ACP) antibodies are highly specific (88–96%) for rheumatoid arthritis...

such increased antibodies are of a monoclonal variety due to the clonal plasma cell and are thus ineffective. Such ineffective antibodies are commonly of...

antibodies to antigens in their cells' nuclei, most frequently to their own DNA. However, Kunkel and Tan found in 1966 that Smith produced antibodies...

infection than the IgG antibodies and disappear faster than IgG antibodies after recovery. In most cases, T. gondii-specific IgM antibodies can first be detected...

to mount defenses against them. In such cases, antitoxin, anti-serum containing antibodies, can sometimes be injected to provide passive immunity. Many...

at all, as U7 snRNP is responsible for processing the 3′ stem-loop of histone pre-mRNA. The two essential components of snRNPs are protein molecules...

of miRNAs, affecting histone methyltransferases, binding to SIRT1 protein to activate transcription, and cooperating with histone methylases and demethylases...

attacked by antiretrovirals and the host immune system. Targets include histone deacetylase (HDAC) which represses transcription and if inhibited can lead...

(April 1, 2005). "Proapoptotic Activity of Cell-Permeable Anti-Akt Single-Chain Antibodies". Cancer Research. 65 (7). Cancer Research: 2815–2824. doi:10...

difference between patients with antibodies indicating recent reactivation of HSV and those without these antibodies in the incidence of Alzheimer's disease...

as a significant decrease in the levels of IgG antibodies, usually alongside IgA antibodies; IgM antibody levels are also decreased in about half of those...

morphea have shown results in higher frequencies of anti-histone and anti-topoisomerase IIa antibodies. Case reports of morphea co-existing with other systemic...

conditions. The main mechanisms of epigenetic alterations are DNA methylation, histone modifications, and regulation by non-coding RNAs. These epigenetic changes...

because Fc receptors bind antibodies attached to cells targeted for destruction by macrophages. Glucocorticoids are potent anti-inflammatories, regardless...

Auto-antibodies against histones have been reported to be involved. Anti-AQP1 could be involved in atypical MS and NMO N-type calcium channel antibodies can...

deleterious effect on the host, because the extracellular exposure of histone complexes could play a role during the development of autoimmune diseases...