In the field of pharmacokinetics, the area under the curve (AUC) is the definite integral of the concentration of a drug in blood plasma as a function...
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service Area under the curve (receiver operating characteristic), a performance measure for binary classifiers Area under the curve (pharmacokinetics), regarding...
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Cmax (pharmacology) (redirect from Tmax (pharmacokinetics))
systemic exposure. Cavg (pharmacology) Area under the curve (pharmacokinetics) Tracy TS (2004). "Pharmacokinetics". In Stitzel RE, Craig CF (eds.). Modern...
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Cavg (redirect from Caverage (pharmacokinetics))
,{\text{ss}}}} is the area under the curve and τ {\displaystyle \tau } the dosing interval. Area under the curve (pharmacokinetics) Cmax (pharmacology)...
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calculating the dimensions of different areas under the curve. The models used in non-linear pharmacokinetics are largely based on Michaelis–Menten kinetics...
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Quinolone antibiotic (category Wikipedia articles incorporating text from the United States Department of Health and Human Services)
1219192. PMC 3357493. PMID 22517853. Bergan T (1988). "Pharmacokinetics of fluorinated quinolones". The quinolones. Academic Press. pp. 119–154. Bergan T,...
63 KB (6,260 words) - 05:59, 12 August 2024
Viloxazine (section Pharmacokinetics)
area-under-the-curve (pharmacokinetics) levels of extended-release viloxazine are proportional over a dosage range of 100 to 400 mg once daily. The time...
35 KB (3,017 words) - 04:42, 22 July 2024
The pharmacokinetics of progesterone, concerns the pharmacodynamics, pharmacokinetics, and various routes of administration of progesterone. Progesterone...
175 KB (18,968 words) - 15:19, 3 July 2024
The pharmacology of estradiol, an estrogen medication and naturally occurring steroid hormone, concerns its pharmacodynamics, pharmacokinetics, and various...
223 KB (26,808 words) - 08:46, 18 May 2024
Drug accumulation ratio (category Pharmacokinetic metrics)
In pharmacokinetics, the drug accumulation ratio (Rac) is the ratio of accumulation of a drug under steady state conditions (i.e., after repeated administration)...
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Bioequivalence (category Pharmacokinetics)
For a pharmacokinetic comparison, the plasma concentration data are used to assess key pharmacokinetic parameters such as area under the curve (AUC),...
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"Comparison of the pharmacokinetics of several polychlorinated biphenyls in mouse, rat, dog, and monkey by means of a physiological pharmacokinetic model". Drug...
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found Amcinonide cream to be the most effective with the highest bio-activity and area under the curve (pharmacokinetics). A French study by Binet et...
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Levmetamfetamine (section Pharmacokinetics)
125.9 ng/mL with single intravenous doses of 0.25 to 0.5 mg/kg. The area-under-the-curve (AUC) levels of levmetamfetamine range from 73.0 to 694.7 ng⋅h/mL...
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Zopiclone (section Pharmacokinetics)
severe chronic kidney failure, the area under the curve value for zopiclone was larger and the half-life associated with the elimination rate constant longer...
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Bioavailability (category Pharmacokinetic metrics)
equals the ratio of comparing the area under the plasma drug concentration curve versus time (AUC) for the extravascular formulation to the AUC for the intravascular...
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Pharmacology (redirect from Understanding the Value of Pharmaceuticals)
Pharmacology is the science of drugs and medications, including a substance's origin, composition, pharmacokinetics, pharmacodynamics, therapeutic use...
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Vortioxetine (section Pharmacokinetics)
Nomikos G (June 2018). "Vortioxetine: Clinical Pharmacokinetics and Drug Interactions". Clinical Pharmacokinetics. 57 (6): 673–686. doi:10.1007/s40262-017-0612-7...
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Leon Aarons (category Academics of the University of Manchester)
in the areas of pharmacodynamics and pharmacokinetics. He lives in the United Kingdom and from 1976 has been a professor of pharmacometrics at the University...
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Docetaxel (section Pharmacokinetics)
L based on the mean BSA (body surface area) of 1.68 m2. Area under the plasma concentration-time curve had a mean value of 2.8 mg.h/L. The Cmax of docetaxel...
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Oral EC586 showed area-under-the-curve (AUC) levels that were more than 100-fold greater than those of oral testosterone propionate, the C17β propionate...
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Hydrocodone (section Pharmacokinetics)
PMID 26614499. Jenkins AJ (9 October 2007). "Pharmacokinetics of Specific Drugs". In Karch SB (ed.). Pharmacokinetics and Pharmacodynamics of Abused Drugs. CRC...
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Anastrozole (section Pharmacokinetics)
"Anastrozole". Lønning P (2003). "Clinical pharmacokinetics of aromatase inhibitors and inactivators". Clinical Pharmacokinetics. 42 (7): 619–631. doi:10...
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Biological half-life Atomoxetine The pharmacokinetics of atomoxetine are similar in children, teenagers and adults. Pharmacokinetics of atomoxetine has not been...
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Atorvastatin (section Pharmacokinetics)
elevation in the area under the curve (AUC), resulting in a minor drug-drug interaction. The American Heart Association states that the combination of...
100 KB (9,421 words) - 00:58, 12 July 2024
Tetrahydrocannabinol (section Pharmacokinetics)
peak concentrations of oral THC by 4 hours on average and increases area-under-the-curve exposure by 2.9-fold, but peak concentrations are not significantly...
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Omeprazole (section Pharmacokinetics)
pathways, and inhibition of these enzymes results in a higher area under the curve (i.e., the total effect over time of a given dose). Other examples of...
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Ondansetron (section Pharmacokinetics)
87% higher area-under-curve or AUC (P < 0.01) compared to S–(+)–ondansetron, indicating that the R enantiomer is metabolized more slowly. The chiral carbon...
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Tenofovir disoproxil (section Pharmacokinetics)
(2006). "Pharmacokinetics and dosing recommendations of tenofovir disoproxil fumarate in hepatic or renal impairment". Clinical Pharmacokinetics. 45 (11):...
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Amitriptyline (section Pharmacokinetics)
Hollister L (1985). "Discrepancies between pharmacokinetic studies of amitriptyline". Clinical Pharmacokinetics. 10 (3): 257–268. doi:10.2165/00003088-198510030-00005...
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