bioinformatics, the BLOSUM (BLOcks SUbstitution Matrix) matrix is a substitution matrix used for sequence alignment of proteins. BLOSUM matrices are used...
22 KB (2,553 words) - 08:59, 31 July 2024
evolutionary change. The BLOSUM-62 matrix is one of the best substitution matrices for detecting weak protein similarities. BLOSUM matrices with high numbers...
19 KB (2,483 words) - 14:32, 2 July 2024
that the BLOSUM matrices are much more effective. The BLOSUM series were generated by comparing a number of divergent sequences. The BLOSUM series are...
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Substitution matrix (section BLOSUM)
approximated by compounding small changes that occur over short time scales. The BLOSUM (BLOck SUbstitution Matrix) series of matrices rectifies this problem. Henikoff...
15 KB (2,105 words) - 13:47, 21 December 2023
by the BLOSUM matrices. Although both matrices produce similar scoring outcomes they were generated using differing methodologies. The BLOSUM matrices...
31 KB (4,156 words) - 21:26, 1 April 2024
scoring matrices, each with further alterations for specific scenarios: PAM BLOSUM When aligning sequences there are often gaps (i.e. indels), sometimes large...
25 KB (3,235 words) - 19:47, 13 June 2024
became a teacher at St. Friedeswiede. Blosum Pricket (ブロサム=プリケト, Burosamu Puriketo) Voiced by: Hōchū Ōtsuka Blosum Pricket is the Marquis of the town of...
27 KB (2,142 words) - 15:22, 31 May 2024
together with his wife Jorja Henikoff, introduced the BLOSUM substitution matrices. The BLOSUM matrices are widely used for sequence alignment of proteins...
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of the available sequences against the query by a scoring matrix such as BLOSUM 62. The highest scoring sequences represent the closest relatives of the...
16 KB (1,312 words) - 03:24, 26 August 2024
substitutions may be identified using substitution matrices such as PAM and BLOSUM. Highly scoring alignments are assumed to be from homologous sequences....
47 KB (4,993 words) - 23:44, 13 August 2024
search results, although the BLOSUM matrices have superseded the PAM log-odds matrices in this context because the BLOSUM matrices appear to be more sensitive...
65 KB (8,833 words) - 03:00, 28 June 2024
lyrics. The concept is adapted from a sequence alignment technique using BLOSUM (BLOcks SUbstitution Matrix). They were able to detect rhymes undetectable...
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amino acid mutations. Another common series of scoring matrices, known as BLOSUM (Blocks Substitution Matrix), encodes empirically derived substitution probabilities...
56 KB (6,858 words) - 22:25, 18 August 2024
amino acids is usually more complicated than that of the bases. See PAM, BLOSUM. Gap penalty designates scores for insertion or deletion. A simple gap penalty...
36 KB (4,659 words) - 22:15, 23 August 2024
suspicious plants. Blosum stops her and explains the area is home to many dangerous "mystery spots". Someone then informs Blosum about a sick resident...
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similarity function σ ( x , y ) {\displaystyle \sigma (x,y)} (e.g. PAM, BLOSUM,...) affine gap penalty: g ( k ) = α + β k {\displaystyle g(k)=\alpha +\beta...
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J3 (= TIM), TVM, GTR), 14 empirical models of amino acid substitution (BLOSUM, cpREV, Dayhoff, JTT, LG, mtArt, mtMam, mtREV, PMB, rtREV, betHIV, witHIV...
6 KB (591 words) - 10:51, 26 June 2024