Bilirubin glucuronide is a water-soluble reaction intermediate over the process of conjugation of indirect bilirubin. Bilirubin glucuronide itself belongs...

Bilirubin di-glucuronide is a conjugated form of bilirubin formed in bilirubin metabolism. The hydrophilic character of bilirubin diglucuronide enables...

first to bilirubin glucuronide and then to bilirubin diglucuronide, making it soluble in water: the conjugated version is the main form of bilirubin present...

baby syndrome. Bilirubin is excreted in the bile as bilirubin diglucuronide (80%), bilirubin glucuronide (20%), and unconjugated bilirubin (< 1%). In the...

with colouration that varies from pink to violet: In acid medium Bilirubin glucuronide + Diazonium salt→ Azo dye (violet) False positive reactions can...

condition describing an elevation of blood bilirubin level due to the inability to properly metabolise or excrete bilirubin, a product of erythrocytes breakdown...

residues into bilirubin diglucuronide, and secreted into the small intestine as bile. In the small intestine, some bilirubin glucuronide is converted back...

conjugates from hepatocytes into bile. Impaired biliary excretion of bilirubin glucuronides is due to a mutation in the canalicular multiple drug-resistance...

inhibition, MRP2 is an apical efflux transporter that mainly exports bilirubin glucuronide and glutathione into bile. However, MRP2 is also the preferential...

hepatocytes and bacteria) which hydrolyzes bilirubin glucuronides and increases the amount of unconjugated bilirubin in bile. Between 4% and 20% of stones...

of the white part of the eyes and skin in a newborn baby due to high bilirubin levels. Other symptoms may include excess sleepiness or poor feeding....

involved in drug metabolism of substances such as drugs, pollutants, bilirubin, androgens, estrogens, mineralocorticoids, glucocorticoids, fatty acid...

namely, excessive bilirubin synthesis, liver bilirubin uptake malfunction, and bilirubin conjugation compromise. As to excessive bilirubin synthesis, both...

deconjugate bilirubin diglucuronide releasing free bilirubin, which can either be reabsorbed or reduced to urobilinogen by the bacterial enzyme bilirubin reductase...

conjugated at its 3-hydroxy group into lorazepam glucuronide which is then excreted in the urine. Lorazepam glucuronide has no demonstrable CNS activity in animals...

Escherichia coli in bile. In humans, the majority of bilirubin is excreted in the bile as bilirubin glucuronide.[citation needed] Hepatolithiasis is associated...

pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This...

activity, may lead to severe toxicity. Also, UGT1A1 conjugates bilirubin and bilirubin glucuronidation is another risk factor for increased toxicity The...

metabolites via Phase II metabolism by conjugation with sulfate and glucuronide, with a small portion being oxidized via the cytochrome P450 enzyme system...

lysosome. In the gut, brush border β-glucuronidase converts conjugated bilirubin to the unconjugated form for reabsorption. β-Glucuronidase is also present...

blood 5-5.7 ×10−4 Bile acids Digestive function, bilirubin excretion 2-30 ×10−6 3-30 ×10−6 Bilirubin Hemoglobin metabolite 2-14 ×10−6 1-10 ×10−6 Biotin...

during the first few weeks of life as it interferes with the action of bilirubin and can worsen neonatal jaundice. In HIV-positive people, the combination...

(ASTTooltip aspartate aminotransferase, ALTTooltip alanine aminotransferase, bilirubin, LDHTooltip lactic dehydrogenase, ALPTooltip alkaline phosphatase), hepatotoxicity...

product of haem breakdown, bilirubin, most often the result of liver damage as it is the liver's responsibility to clear bilirubin. It tends to produce less...

(e.g., β-naphthoflavone)) Tapinarof (benvitimod) Tetrapyroles (e.g., bilirubin) Tryptophan derivatives (e.g., indigo dye, indirubin) Antagonists: 7-Ketocholesterol...

(e.g., β-naphthoflavone)) Tapinarof (benvitimod) Tetrapyroles (e.g., bilirubin) Tryptophan derivatives (e.g., indigo dye, indirubin) Antagonists: 7-Ketocholesterol...

Docetaxel [D-penicillamine2,5]enkephalin (DPDPE) Enalapril Estradiol-17β-glucuronide 5–25 Estrone-3-sulfate Fexofenadine Fluvastatin Fluo-3 Glutathione (GSH)...

hydrophilic estrogen conjugates such as estrone sulfate and estradiol glucuronide, which require active transport via specific membrane transport proteins...

cholestatic jaundice, cholelithiasis, transient increases in transaminases and bilirubin, erythema multiforme, hyperpigmentation, muscle cramps, dysmenorrhea,...

as well as androstenedione, total testosterone and 3a-androstanediol glucuronide, in young women with PCOS [41,59]. These effects may be due to inhibition...