T-box transcription factor T (redirect from Brachyury)
transcription factor T, also known as Brachyury protein, is encoded for in humans and other apes by the TBXT gene. Brachyury functions as a transcription factor...
34 KB (3,996 words) - 06:03, 11 November 2024
been affected by chordoma. In four of these families, duplication of the brachyury gene was found to be responsible for causing chordoma. A possible association...
21 KB (2,187 words) - 14:39, 28 May 2024
protein encoded was named brachyury, Greek for "short-tail". In mice this gene is named Tbxt, and in humans it is named TBXT. Brachyury has been found in all...
10 KB (1,078 words) - 03:27, 30 November 2023
conditions derived from directed differentiation of ESCs in adherent culture Brachyury (T/Bra), a gene which marks the primitive streak and the site of gastrulation...
15 KB (1,666 words) - 19:23, 24 July 2024
initiation of the Manx Cat Genome Project (below), genetic mutations in the brachyury gene were shown to be responsible for failure of tail development in the...
71 KB (7,692 words) - 07:19, 3 November 2024
Xbra is a homologue of Brachyury (T) gene for Xenopus. It is a transcription activator involved in vertebrate gastrulation which controls posterior mesoderm...
4 KB (507 words) - 13:04, 18 August 2023
identification of notochord enhancers comprising the regulatory landscape of the brachyury locus in mouse. Development (Cambridge, England), 150(22). https://doi...
21 KB (2,364 words) - 11:30, 5 October 2024
acids of DNA T, gene and protein symbol for the transcription factor brachyury Thoracic vertebrae T-1 through T-12 T wave, the repolarization wave of...
7 KB (967 words) - 17:36, 29 September 2024
despite these obstacles Ephrussi managed to conclude from studies of brachyury in mice that intrinsic factors (i.e. genes) play a key role in development...
8 KB (889 words) - 11:00, 22 October 2024
epiblast cells that traverse through the primitive streak (e.g. transient brachyury up regulation and the cellular changes associated with an epithelial to...
47 KB (5,439 words) - 23:44, 9 November 2024
Satoh, Nori (September 2000). "The expression of nonchordate deuterostome Brachyury genes in the ascidian Ciona embryo can promote the differentiation of...
5 KB (448 words) - 08:53, 25 April 2023
doi:10.1038/346561a0. PMID 2165569. S2CID 4356509. "T brachyury transcription factor". T - T brachyury transcription factor - Genetics Home Reference. Genome...
35 KB (2,420 words) - 20:57, 24 August 2024
on developmental genetics. Her research showed that mutations in the Brachyury gene of the mouse caused the aberrant development of the posterior portion...
11 KB (984 words) - 08:59, 13 September 2024
(brakhús) amphibrach, brachistochrone, brachycephaly, brachydactyly, brachyury, dibrach, tribrach brady-, bradys- slow Greek βραδύς (bradús), βράδος...
2 KB (1,500 words) - 22:12, 13 November 2024
pointer", the braque du Bourbonnais is sometimes born with a short tail (brachyury) or no tail at all (anury). The gene responsible for this characteristic...
6 KB (599 words) - 11:18, 6 July 2024
lophotrochozoans: insight from the expression patterns of Hox, Otx, and brachyury". Evolution & Development. 11 (5): 582–589. doi:10.1111/j.1525-142X.2009...
10 KB (1,070 words) - 06:14, 25 July 2024
factors (Vg1, Nodal, Wnt8C, FGF8 and Chordin) and transcription factors (Brachyury and Goosecoid) adjacent to the site of streak formation is required for...
23 KB (2,803 words) - 06:48, 25 October 2024
parallels to embryonic development such as symmetry-breaking, localised brachyury expression, the formation of the embryonic axes (anteroposterior, dorsoventral...
45 KB (4,513 words) - 01:22, 22 June 2024
stomochord, or between the notochord and any hemichordate structure. The Brachyury (T) gene, which is expressed in the ascidian and other chordates notochord...
2 KB (186 words) - 14:19, 6 November 2020
shown that brachyury is overexpressed in various human carcinomas, both in the primary tumor and in metastatic sites, and that high brachyury expression...
5 KB (504 words) - 18:37, 6 July 2024
Paris. There she made a genetic and oncology research career discovering Brachyury gene in mice. Also she established RIII mouse strain which helped to discover...
5 KB (461 words) - 19:53, 2 November 2024
lophotrochozoans: insight from the expression patterns of Hox, Otx, and brachyury". Evol Dev. 11 (5): 582–589. doi:10.1111/j.1525-142x.2009.00364.x. PMID 19754714...
14 KB (1,666 words) - 03:46, 31 October 2024
was a Brachyury gene, a marker of mesoderm differentiation and is only slightly expressed in undifferentiated embryonic stem cells. "Brachyury" was induced...
28 KB (3,692 words) - 22:45, 3 December 2023
tumor cells can adapt to promote disease recurrence and progression. Brachyury, Axl, MEK, and Aurora kinase A are molecular drivers of these programs...
59 KB (6,836 words) - 03:14, 26 August 2024
transcription factors (2). In particular, three T box transcription factors, Brachyury (frogs) or No tail (fish) (10), VegT (frog) or Spadetail (fish), and Tbx6...
10 KB (1,399 words) - 14:41, 14 July 2024
these simple chordates and in higher vertebrates. As an example, the brachyury gene and the homolog of the PAX2 gene both play a similar role in the...
7 KB (787 words) - 16:00, 25 October 2024
(brakhús) amphibrach, brachistochrone, brachycephaly, brachydactyly, brachyury, dibrach, tribrach brady-, bradys- slow Greek βραδύς (bradús), βράδος...
14 KB (134 words) - 18:51, 9 August 2024
has, however, already been possible to identify several genes, such as Brachyury and TBX2/TBX3, which are homologous to corresponding base-pair sequences...
51 KB (6,057 words) - 07:39, 8 October 2024
mouse chromosome 17 and characterization of the enu-induced quaking and brachyury alleles (1987) Academic work Institutions University of Toronto Baylor...
6 KB (481 words) - 08:31, 17 October 2024
where cells contribute to ventral and posterior mesoderm. Adding to this, Brachyury and caudal homologues are expressed circumferentially around the blastopore...
11 KB (1,436 words) - 12:50, 29 July 2024