Breakage-fusion-bridge (BFB) cycle (also breakage-rejoining-bridge cycle) is a mechanism of chromosomal instability, discovered by Barbara McClintock in...

Bad Break (disambiguation) Breakages, Limited, a fictional corporation in 1928 play The Apple Cart Breakage-fusion-bridge cycle, a mechanism of chromosomal...

There, she was highly productive and continued her work with the breakage-fusion-bridge cycle, using it to substitute for X-rays as a tool for mapping new...

Martínez-A C, van Wely KH (July 2013). "Chromothripsis: Breakage-fusion-bridge over and over again". Cell Cycle. 12 (13): 2016–2023. doi:10.4161/cc.25266. PMC 3737304...

to transcriptional elements and contact with enhancers. The “breakage-fusion-bridge” cycle, which describes an event where telomere loss causes the repeated...

duplications, balanced translocations, unbalanced translocations, breakage-fusion-bridge cycle mediated complex DNA rearrangements, and chromothripsis events...

that the breakage-fusion-bridge cycle involves ring chromosomes too. Particularly, these ring chromosomes involved in breakage-fusion-bridge cycles have a...

dicentric chromosomes form, a series of events can occur called a breakage-fusion-bridge cycle: Spindle fibers attach onto both centromeres in different locations...

been hypothesized that breakage in this area is the main culprit behind the cancers that EBV increases the chance of. The breakage is also dose-dependent...

structural variation classes of at least 200kb in size, including breakage-fusion-bridge cycles and chromothripsis events, as well as balanced inversions, and...

DNA repair probes. Lepidoptera also do not show the classical breakage-fusion-bridge cycle that is a characteristic of dominant lethals induced in Diptera...

circular or ring chromosome. This undergoes hundreds of circular breakage-fusion-bridge cycles, causing random amplification and deletion of DNA with selection...

diploid organism. The haplodiplontic life cycle can be considered a fusion of the diplontic and haplontic life cycles.[citation needed] Meiosis occurs in all...

likely what begin tumorigenesis, but once cells begin the breakage-fusion-bridge (BFB) cycle, they are able to mutate at much faster rates. (See genome...

length away from the closest restriction sites are the results of physical breakage of the chromatin or non-canonical nuclease activities. Because these reads...

ISBN 978-0-07-136333-4. Patterson, B. D.; Neiburger, E. J.; Kasiki, S. M. (2003). "Tooth Breakage and Dental Disease as Causes of Carnivore–Human Conflicts". Journal of...

This telomere loss in turn can lead to telomere end-to-end fusions, fusion-bridge-breakage cycles and genome instability, which is responsible for the heightened...

thus avoids the random insertion and deletions associated with DNA strand breakage. It is only appropriate for precise editing requiring single nucleotide...

Rupa, DS; Hasegawa, LS (2000). "Detection of hyperdiploidy and chromosome breakage in interphase human lymphocytes following exposure to the benzene metabolite...

began with chromosome break in below the gene, and subsequent cycles of bridge-breakage-fusion formations result in large intrachromosomal repeats. The over...

over 2,500 km (1,600 mi) of underground water mains, which are subject to breakage due to corrosion and pressure from extreme dry, wet, or cold soil conditions...

inversions, which are rotations in regions of a chromosome due to chromosomal breakages or intra-chromosomal recombinations. Inversions that exclude the centromere...

of the coral, like light exposure and wave action, and events such as breakages. Corals reproduce both sexually and asexually. An individual polyp uses...

S2CID 42615999. Petit MM, Swarts S, Bridge JA, Van de Ven WJ (October 1998). "Expression of reciprocal fusion transcripts of the HMGIC and LPP genes...

DSB-telomere fusions after knockdown of DNA-PK. Cells containing telomere-deficient chromosomes will either senesce or undergo breakage-fusion-bridge (B/F/B)...