Brincidofovir, sold under the brand name Tembexa, is an antiviral drug used to treat smallpox. Brincidofovir is a prodrug of cidofovir. Conjugated to a...
25 KB (2,193 words) - 01:06, 23 July 2024
low-resource setting, and helped to organise the trial for the drug brincidofovir during the 2014 Ebola virus outbreak. Lang started her career working...
11 KB (1,021 words) - 08:09, 15 August 2024
determine its safety and effectiveness in humans. Another example is brincidofovir. In June 2021, the FDA approved this drug for the treatment of smallpox...
17 KB (1,821 words) - 08:34, 23 August 2024
significant risks from tecovirimat and low certainty evidence that suggests brincidofovir may cause mild liver injury. Pain is common and may be severe; supportive...
29 KB (4,154 words) - 08:56, 19 August 2024
basis in the event of a bioterror incident involving smallpox cases. Brincidofovir, a cidofovir derivative with much higher activity against smallpox that...
15 KB (1,361 words) - 05:27, 1 July 2024
military and maintained in the Strategic National Stockpile. In June 2021, brincidofovir was approved for medical use in the United States for the treatment...
164 KB (17,778 words) - 18:14, 22 August 2024
significant risks from tecovirimat and low certainty evidence that suggests brincidofovir may cause mild liver injury. Pain is common and may be severe; supportive...
76 KB (6,770 words) - 04:16, 25 August 2024
Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
34 KB (3,208 words) - 06:40, 13 July 2024
but no proven, effective therapy is known in humans. For example, Brincidofovir (1-O-hexadecyloxypropyl-cidofovir /CMX001) available as Tembexa, suppresses...
23 KB (2,414 words) - 19:20, 9 February 2024
the hospital contacted Chimerix, a biotechnology company developing Brincidofovir to combat the disease. The next day, Duncan's organs were failing, and...
118 KB (11,914 words) - 14:42, 21 August 2024
Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
281 KB (26,329 words) - 18:10, 24 August 2024
Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
20 KB (2,319 words) - 14:27, 8 June 2024
Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
43 KB (4,641 words) - 06:47, 6 May 2024
Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
21 KB (2,144 words) - 11:04, 25 August 2024
Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
10 KB (1,134 words) - 14:30, 8 August 2024
Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
41 KB (1,579 words) - 23:38, 3 July 2024
Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
77 KB (6,989 words) - 14:39, 21 August 2024
Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
51 KB (4,931 words) - 14:57, 5 August 2024
pediatric access to investigational drugs when his family's request for brincidofovir was declined by the drug manufacturer, Chimerix. The company reversed...
23 KB (2,650 words) - 21:37, 25 July 2024
Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
29 KB (2,688 words) - 04:47, 7 January 2024
Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
51 KB (5,469 words) - 17:00, 17 August 2024
Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
21 KB (2,198 words) - 10:12, 15 August 2024
Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
63 KB (3,859 words) - 15:30, 14 August 2024
Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
16 KB (1,566 words) - 08:15, 1 May 2024
Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
16 KB (1,424 words) - 07:30, 6 May 2024
Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
35 KB (3,139 words) - 21:09, 12 August 2024
Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
17 KB (1,997 words) - 02:23, 15 August 2024
Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
15 KB (2,227 words) - 14:54, 17 August 2024
Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
11 KB (726 words) - 14:28, 16 August 2024
Forest ebolavirus TAFV Zaire ebolavirus EBOV Drug candidates BCX4430 Brincidofovir DZNep Favipiravir FGI-103 FGI-104 FGI-106 JK-05 Lamivudine mAb114 TKM-Ebola...
26 KB (2,737 words) - 07:49, 20 July 2024