C3b is the larger of two elements formed by the cleavage of complement component 3, and is considered an important part of the innate immune system. C3b...
9 KB (1,157 words) - 21:44, 31 December 2023
pathways that opsonize and kill pathogens. The pathway is triggered when the C3b protein directly binds a microbe. It can also be triggered by foreign materials...
7 KB (865 words) - 13:08, 7 September 2024
the alternative pathway, C3b binds to Factor B. Factor D releases Factor Ba from Factor B bound to C3b. The complex of C3b(2)Bb is a protease which cleaves...
41 KB (5,016 words) - 12:33, 9 September 2024
(C4b2b, historically referred C4b2a), which cleaves the C3 protein. The C3b component of the cleaved C3 binds to C3 convertase (C4b2b) to generate C5...
16 KB (1,877 words) - 12:56, 3 November 2024
precursor of some cytokines such as ASP, and C3b serves as an opsonizing agent. Factor I can cleave C3b into C3c and C3d, the latter of which plays a...
13 KB (1,556 words) - 13:28, 23 September 2024
innate opsonization include C4b, C3b and iC3b. In the alternative pathway of complement activation, circulating C3b is deposited directly onto antigens...
13 KB (1,529 words) - 18:57, 23 October 2024
C3b inactivator in the alternative pathway. C3b has different binding site for C3bINA, β1H, factor B and properdin. Binding β1H to C3b increases C3bINA...
10 KB (1,319 words) - 09:52, 27 February 2024
Stearman C3 (redirect from Stearman C3B)
needed] Although there were several versions of the C3, most were either the C3B and the C3R. A few C3s were approved for float operations.: 59, 198–199 ...
8 KB (780 words) - 21:55, 27 March 2024
Complement receptor type 1 (CR1) also known as C3b/C4b receptor or CD35 (cluster of differentiation 35) is a protein that in humans is encoded by the...
22 KB (2,904 words) - 06:22, 17 August 2024
C-3-A/B mine (redirect from C3B mine)
The Expal C-3-A and C-3-B are round Spanish rubber modified polystyrene cased anti-tank blast mines . The mines differ only in minor detail. The mine is...
1 KB (126 words) - 19:47, 5 February 2022
Coloni C3 (redirect from Coloni C3B)
frequently failed to pre-qualify for races during 1989. It was updated to the C3B for the 1990 season, with the Cosworth DFR being replaced by a Subaru 1235...
15 KB (1,177 words) - 10:41, 17 December 2022
convertase differ in their C3b requirement. C3-convertase (C3bBb) need only one molecule of C3b to form, whereas two or more C3b are required for generation...
12 KB (1,661 words) - 09:29, 27 February 2024
activity for Factor I–mediated C3b cleavage, and decay accelerating activity against the alternative pathway C3-convertase, C3bBb. Factor H exerts its protective...
29 KB (3,486 words) - 10:30, 30 August 2024
(CD46) Decay Accelerating Factor, DAF (CD55) Protectin (CD59) Complement C3b/C4b Receptor 1, CR1 (CD35) Complement Regulator of the Immunoglobulin Superfamily...
16 KB (1,942 words) - 09:32, 27 February 2024
glycine-rich beta-glycoprotein, heat-labile factor, C3 convertase, C3b,Bb,CVF,Bb,C5 convertase, (C3b)n,Bb, complement C 3(C 5) convertase (amplification), alternative...
2 KB (256 words) - 21:14, 1 September 2023
factor I cleaves C3b. Complement receptors on white blood cells are able to bind iC3b, so iC3b functions as an opsonin. Unlike intact C3b, iC3b cannot associate...
788 bytes (100 words) - 16:02, 1 July 2019
proteins formed by the cleavage of complement component 3; the other is C3b. C3a is a 77 residue anaphylatoxin that binds to the C3a receptor (C3aR)...
17 KB (2,036 words) - 05:36, 19 February 2024
$USD3.9 Billion Buildings O4H4 (Signature Tower), O2, O1B, O1AH1, H3C3A, C5, C3B, P5, H2A, R1, R2 Size 16.64 hectares Leasable area 1.83 million square metres...
8 KB (703 words) - 15:49, 26 October 2024
gene. CR2 is involved in the complement system. It binds to iC3b (inactive derivative of C3b), C3dg, or C3d. B cells express CR2 on their surfaces, allowing...
14 KB (1,829 words) - 12:12, 6 October 2024
which had been used the previous season, was extensively modified into the "C3B" specification to be suitable for use with the Subaru 1235, and Bertrand...
11 KB (1,023 words) - 09:36, 24 February 2023
is facilitated by C3b opsonization. Iptacopan acts proximally in the alternative pathway of the complement cascade to control both C3b-mediated EVH and...
13 KB (816 words) - 02:44, 12 October 2024
regulates the complement system on the cell surface. It recognizes C4b and C3b fragments that are created during activation of C4 (classical or lectin pathway)...
8 KB (962 words) - 14:13, 29 January 2023
the original migration into the Americas. Membership in haplogroups Q and C3b implies Indigenous American patrilineal descent. The micro-satellite diversity...
135 KB (11,083 words) - 03:01, 4 November 2024
complex (MAC) or can bind the antibody, aiding phagocytosis by macrophages (C3b). This is one type of "penicillin allergy".[citation needed] In about half...
26 KB (3,094 words) - 18:23, 8 October 2024
bacteria. CR3 also recognizes iC3b when bound to the surface of foreign cells. iC3b is generated by proteolysis of C3b and binding to the receptor causes...
9 KB (1,138 words) - 00:32, 9 November 2023
DC-9-51 12 1993 Former Eastern Air Lines fleet. Northrop Alpha 14 1931 1935 Sikorsky S-61L 1 Unknown Unknown Helicopter Stearman C3B 1 Unknown Unknown...
78 KB (8,597 words) - 03:53, 29 October 2024
Phagocytic efficacy can be enhanced by opsonization. Plasma derived complement C3b and antibodies that exude into the inflamed tissue during the vascular phase...
94 KB (9,545 words) - 02:59, 25 October 2024
(ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties...
8 KB (992 words) - 05:25, 1 January 2024
Complement factor I, also known as C3b/C4b inactivator, is a protein that in humans is encoded by the CFI gene. Complement factor I (factor I) is a protein...
18 KB (2,243 words) - 04:09, 10 March 2024
The properdin promotes the association of C3b with Factor B and provides a focal point for the assembly of C3bBb on a surface. It binds to preformed alternative...
3 KB (418 words) - 01:13, 3 September 2023