• Thumbnail for PTPRC
    PTPRC (redirect from CD45 antigen)
    enzyme that, in humans, is encoded by the PTPRC gene. PTPRC is also known as CD45 antigen (CD stands for cluster of differentiation), which was originally...
    16 KB (1,959 words) - 05:58, 13 August 2024
  • Thumbnail for T helper cell
    CD45 and Csk. CD45 activates Lck by dephosphorylating a tyrosine in its C-terminal tail, while Csk phosphorylates Lck at that site. The loss of CD45 produces...
    54 KB (6,597 words) - 14:51, 21 July 2024
  • groups CD45+ Granulocyte CD45+, CD11b, CD15+, CD24+, CD114+, CD182+ Monocyte CD4, CD45+, CD14+, CD114+, CD11a, CD11b, CD91+, CD16+ T lymphocyte CD45+, CD3+...
    14 KB (1,368 words) - 17:53, 4 September 2024
  • from it. CD45. CD45 is mainly produced in blood cells. In humans it has been shown to be able to act on JAK1 and JAK3, whereas in mice, CD45 is capable...
    62 KB (6,845 words) - 18:30, 22 August 2024
  • Thumbnail for Reed–Sternberg cell
    predominance type where they are negative, but are usually positive for CD20 and CD45. The presence of these cells is necessary in the diagnosis of Hodgkin lymphoma...
    6 KB (696 words) - 16:23, 14 October 2023
  • Thumbnail for B cell
    receptors diffuse through the membrane coming into contact with Lck and CD45 in equal frequency, rendering a net equilibrium of phosphorylation and non-phosphorylation...
    32 KB (3,752 words) - 22:20, 13 July 2024
  • fragment C3b of complement. They express LCAs (leucocyte common antigens) CD45, CD14, CD33, and CD4 (also expressed by T helper cells). These histiocytes...
    6 KB (609 words) - 12:00, 10 August 2024
  • CD3 complex) and factors that inhibit signalling (tyrosine phosphatases CD45 and CD148). In the resting T-cell, all molecules are repeatedly colliding...
    10 KB (1,195 words) - 05:18, 29 April 2024
  • Thumbnail for HNRNPLL
    activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development...
    3 KB (392 words) - 21:06, 3 March 2023
  • Thumbnail for California's 45th congressional district
    Election Returns: District Definitions California Voter Foundation map - CD45 33°42′51″N 117°40′06″W / 33.71417°N 117.66833°W / 33.71417; -117.66833...
    53 KB (1,621 words) - 19:43, 6 August 2024
  • Thumbnail for Receptor tyrosine kinase
    surface receptors that play a positive role in cell signaling proliferation. Cd45, a cell surface glycoprotein, plays a critical role in antigen-stimulated...
    28 KB (3,078 words) - 07:46, 3 June 2024
  • Thumbnail for Multiple myeloma
    cells are often CD56, CD38, CD138, and CD319 positive and CD19, CD20, and CD45 negative. Flow cytometry is often used to establish the clonal nature of...
    131 KB (13,506 words) - 14:36, 4 September 2024
  • Thumbnail for Bone marrow
    Liu X, Lu H, Jiang C, Cui X, Yu L, Fu X, Li Q, Wang J (2015). "CXCR4(+)CD45(-) BMMNC subpopulation is superior to unfractionated BMMNCs for protection...
    34 KB (3,634 words) - 08:49, 6 August 2024
  • Thumbnail for Hodgkin lymphoma
    as large often bi-nucleated cells with prominent nucleoli and an unusual CD45−, CD30+, CD15+/− immunophenotype. In approximately 50% of cases, the Reed–Sternberg...
    87 KB (8,529 words) - 04:57, 2 September 2024
  • Thumbnail for Sivifene
    thought to produce its immunomodulating effects via upregulation of the CD45 T-lymphocyte cell surface receptor. Tesmilifene "Sivifene - AdisInsight"...
    4 KB (229 words) - 12:35, 24 January 2024
  • Thumbnail for PD-L1
    A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55 CD56...
    24 KB (3,052 words) - 08:26, 20 August 2024
  • Thumbnail for Acute myeloid leukemia
    genetically modified versions with altered molecular markers, including CD45, which is present on most blood cells. A treatment would then be applied...
    75 KB (7,430 words) - 15:36, 9 August 2024
  • Thumbnail for CD4
    A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55 CD56...
    22 KB (2,581 words) - 20:03, 21 June 2024
  • Fourth of July (Remix)" – "Born on the Fourth of July (Remix)" MCA Records CD45-18122 Promo; composed and conducted by John Williams. 1989 Born on the Fourth...
    372 KB (7,013 words) - 19:31, 5 September 2024
  • have been reported to express the hematopoietic cell surface markers CD34+, CD45+, as well as collagen. These cells can migrate to wound sites, suggesting...
    3 KB (379 words) - 22:37, 2 August 2024
  • Thumbnail for SFSWAP
    introns. In addition, it also regulates the splicing of fibronectin and CD45 genes. Two transcript variants encoding different isoforms have been identified...
    1 KB (150 words) - 01:11, 4 March 2023
  • Thumbnail for Tyrosin-protein kinase Lck
    such as the membrane protein CD146, the transmembrane tyrosine phosphatase CD45 and C-terminal Src kinase (Csk). In mice, CD146 directly interacts with the...
    36 KB (4,466 words) - 12:30, 11 May 2024
  • Thumbnail for Programmed cell death protein 1
    A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55 CD56...
    39 KB (5,010 words) - 05:27, 17 August 2024
  • cytoskeletal protein talin are clustered. d-SMAC (distal-SMAC) enriched in CD43 and CD45 molecules. New investigations, however, have shown that a "bull’s eye" is...
    15 KB (1,808 words) - 12:45, 29 March 2024
  • Thumbnail for Ewing sarcoma
    t(7;22). Ewing sarcoma cells are positive for CD99 and MIC2, and negative for CD45. The definitive diagnosis is based on histomorphologic findings, immunohistochemistry...
    41 KB (4,430 words) - 13:45, 10 May 2024
  • Thumbnail for List of therapeutic monoclonal antibodies
    leukemia (ALL) Ipilimumab Yervoy mab human CD152 Y melanoma Iomab-B mouse CD45 ablation of bone marrow Iratumumab mab human CD30 (TNFRSF8) Hodgkin's lymphoma...
    136 KB (4,020 words) - 07:14, 15 August 2024
  • is found on human neutrophils, basophils, monocyte, platelets, tonsillar CD45+ dendritic cells, epithelial cells, endothelial cells in intestinal epithelium...
    2 KB (174 words) - 07:42, 5 May 2024
  • A B CD33 CD34 CD35 CD36 CD37 CD38 CD39 CD40 CD41 CD42 a b c d CD43 CD44 CD45 CD46 CD47 CD48 CD49 a b c d e f CD50 51–100 CD51 CD52 CD53 CD54 CD55 CD56...
    11 KB (1,311 words) - 20:50, 18 October 2022
  • Thumbnail for T-cell receptor
    the TCR. Tonic TCR signalling is avoided by the presence of phosphatase CD45 that removes phosphorylation from tyrosine residues and inhibits signal initiation...
    43 KB (5,372 words) - 15:31, 6 August 2024
  • Thumbnail for Mesenchymal stem cell
    CD90 and CD105, while lacking the expression of CD11b, CD14, CD19, CD34, CD45, CD79a and HLA-DR surface markers. MSCs are found throughout the human body...
    43 KB (4,870 words) - 14:42, 29 August 2024