Cav1.4 also known as the calcium channel, voltage-dependent, L type, alpha 1F subunit (CACNA1F), is a human gene. This gene encodes a member of the alpha-1...
8 KB (1,081 words) - 06:22, 30 July 2023
the length of activation. This channel has four isoforms: Cav1.1, Cav1.2, Cav1.3, and Cav1.4. L-type calcium channels are responsible for the excitation-contraction...
17 KB (2,004 words) - 01:57, 7 August 2024
subunit (also known as Cav1.3) is a protein that in humans is encoded by the CACNA1D gene. Cav1.3 channels belong to the Cav1 family, which form L-type...
27 KB (3,339 words) - 18:36, 22 August 2024
type, alpha 1C subunit (also known as Cav1.2) is a protein that in humans is encoded by the CACNA1C gene. Cav1.2 is a subunit of L-type voltage-dependent...
22 KB (2,667 words) - 00:53, 17 July 2024
mutations in the CACNA1F gene, which encodes the voltage-gated calcium channel CaV1.4 expressed heavily in retina. One of the important properties of this channel...
34 KB (2,878 words) - 04:07, 28 July 2024
"Ligand-gated calcium channels inside and out". Current Opinion in Cell Biology. 8 (4): 490–495. doi:10.1016/S0955-0674(96)80025-1. PMID 8791458. Zamponi, Gerald...
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CACNA1C gene, with a single-nucleotide polymorphism in the third intron of the Cav1.2 gene, are associated with a variant of long QT syndrome called Timothy's...
28 KB (3,092 words) - 18:50, 27 October 2023
CatSper1 CatSper2 CatSper3 CatSper4 Cation channels of sperm Cav1.1 Cav1.2 Cav1.3 Cav1.4 Cav2.1 Cell adhesion molecule Cell membrane Cellular component...
15 KB (1,545 words) - 18:32, 17 August 2024
CACNA1F gene, which codes for the αF1-subunit of the L-type calcium channel Cav1.4. The gene is expressed at the active zone of photoreceptor ribbon synapses...
29 KB (3,551 words) - 22:07, 2 January 2024
Cav1.1 also known as the calcium channel, voltage-dependent, L type, alpha 1S subunit, (CACNA1S), is a protein which in humans is encoded by the CACNA1S...
13 KB (1,605 words) - 18:36, 22 August 2024
researchers have also discovered that CAV1 proteins can also influence other endocytic pathways. When CAV1 binds to Cdc42, CAV1 inactivates it and regulates Cdc42...
25 KB (2,980 words) - 14:58, 19 June 2024
Congenital generalized lipodystrophy (section Type 4)
regulation. High levels of Cav1 are normally expressed in adipocytes. Thus, when the CAV1 gene mutates the adipocytes do not have Cav1 and are unable to properly...
18 KB (1,749 words) - 17:26, 23 July 2024
There are three homologous genes of caveolin expressed in mammalian cells: Cav1, Cav2 and Cav3. These proteins have a common topology: cytoplasmic N-terminus...
13 KB (1,461 words) - 21:08, 12 September 2024
Caveolin 1 (redirect from CAV1 (gene))
Caveolin-1 is a protein that in humans is encoded by the CAV1 gene. The scaffolding protein encoded by this gene is the main component of the caveolae...
14 KB (1,555 words) - 20:31, 22 August 2024
propagates to the T-tubules where it triggers the entry of calcium ions via Cav1.1 as well as from the sarcoplasmic reticulum through the associated ryanodine...
17 KB (2,109 words) - 04:56, 30 August 2024
CAMP-dependent pathway (category EC 4.6.1)
β2 adrenergic receptor signaling complex assembled with the Ca2+ channel Cav1.2". Science. 293 (5527): 98–101. doi:10.1126/science.293.5527.98. PMID 11441182...
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features of the neuronal CaV1.3 channels, with important implications for their contribution to control of neuronal function. In 2001, CaV1.2 channels were extensively...
20 KB (2,390 words) - 12:44, 13 April 2024
typically poor. The risk of major adverse cardiovascular events is increased by 3.4 fold if CAV is present on angiography. The frequency of CAV after heart transplantation...
21 KB (1,955 words) - 14:52, 15 September 2023
depolarization or hyperpolarization of the hair cell. Depolarization opens Cav1.3 calcium channels in the basolateral membrane. Hair cells use a system of...
24 KB (2,431 words) - 13:11, 6 July 2024
Cardiac action potential (section Phase 4)
reference also to the SAN action potential. In the ventricular myocyte, phase 4 occurs when the cell is at rest, in a period known as diastole. In the standard...
46 KB (5,430 words) - 18:10, 24 April 2024
Priori, Silvia G.; Sanguinetti, Michael C.; Keating, Mark T. (October 2004). "CaV1.2 Calcium Channel Dysfunction Causes a Multisystem Disorder Including Arrhythmia...
17 KB (1,194 words) - 17:38, 1 October 2024
Q5SY80 2205 CATSPERG HGNC:25243 Q6ZRH7 2206 CATSPERZ HGNC:19231 Q9NTU4 2207 CAV1 HGNC:1527 Q03135 2208 CAV2 HGNC:1528 P51636 2209 CAV3 HGNC:1529 P56539 2210...
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amphetamine and 4-hydroxymethamphetamine;[unreliable medical source?] other minor metabolites include: 4-hydroxyamphetamine, 4-hydroxynorephedrine, 4-hydroxyphenylacetone...
156 KB (15,356 words) - 13:43, 3 October 2024
a variety of excreted metabolic products, including 4-hydroxyamphetamine, 4-hydroxynorephedrine, 4-hydroxyphenylacetone, benzoic acid, hippuric acid, norephedrine...
57 KB (21,441 words) - 18:33, 3 October 2024
Bruton's tyrosine kinase has been shown to interact with: ARID3A BLNK (SLP-65), CAV1, GNAQ, GTF2I, PLCG2, PRKD1, and SH3BP5. GRCh38: Ensembl release 89: ENSG00000010671...
27 KB (2,839 words) - 22:26, 2 October 2024
Cardiotonic agent (section 4) Calcium sensitisers)
(2017-01-24). "Ser1928 phosphorylation by PKA stimulates the L-type Ca2+ channel CaV1.2 and vasoconstriction during acute hyperglycemia and diabetes". Science...
57 KB (5,106 words) - 16:11, 11 August 2024
Long QT syndrome (redirect from Long QT syndrome 4)
disorder. Timothy syndrome is caused by variants in the calcium channel Cav1.2 encoded by the gene CACNA1c. The following is a list of genes associated...
64 KB (6,615 words) - 10:17, 11 August 2024
mechanisms of 1,4-dihydropyridine derivatives to L-type calcium channel Cav1.2: a molecular modeling study". Molecular BioSystems. 12 (2): 379–390. doi:10...
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associated with one of its ultimate effectors, the class C L-type calcium channel CaV1.2.[citation needed] This receptor-channel complex is coupled to the Gs G...
33 KB (3,418 words) - 12:27, 19 September 2024