• Chiral resolution, or enantiomeric resolution, is a process in stereochemistry for the separation of racemic mixture into their enantiomers. It is an...
    7 KB (896 words) - 02:15, 5 April 2024
  • Thumbnail for Chirality (chemistry)
    In chemistry, a molecule or ion is called chiral (/ˈkaɪrəl/) if it cannot be superposed on its mirror image by any combination of rotations, translations...
    31 KB (3,668 words) - 05:48, 29 October 2024
  • reaction with a chiral catalyst or reagent, resulting in an enantioenriched sample of the less reactive enantiomer. As opposed to chiral resolution, kinetic...
    57 KB (6,914 words) - 13:54, 30 July 2024
  • Thumbnail for Chiral derivatizing agent
    analytical chemistry, a chiral derivatizing agent (CDA), also known as a chiral resolving reagent, is a derivatization reagent that is a chiral auxiliary used...
    15 KB (1,818 words) - 23:00, 4 December 2023
  • racemate into its components, the individual enantiomers, is called a chiral resolution. Various methods exist for this separation, including crystallization...
    15 KB (1,826 words) - 18:39, 29 July 2024
  • A chiral phenomenon is one that is not identical to its mirror image (see the article on mathematical chirality). The spin of a particle may be used to...
    22 KB (3,265 words) - 00:34, 24 September 2024
  • reciprocal of the unit in the last place Resolution (beam engine), an early steam engine at Coalbrookdale Chiral resolution, a process in stereochemistry for...
    7 KB (838 words) - 03:06, 27 August 2024
  • Thumbnail for Enantioselective synthesis
    reaction (or reaction sequence) in which one or more new elements of chirality are formed in a substrate molecule and which produces the stereoisomeric...
    41 KB (4,726 words) - 05:21, 27 May 2024
  • Thumbnail for Galantamine total synthesis
    Chemical yield: 1.4%. In addition they isolated (−)-narwardine by chiral resolution from a mixture of racemic narwedine and 0.5 equivalents of (+)-galanthamine...
    15 KB (1,662 words) - 02:08, 18 September 2024
  • Thumbnail for 1-Phenylethylamine
    C6H5CH(NH2)CH3. This primary amine is a colorless liquid is often used in chiral resolutions. Like benzylamine, it is relatively basic and forms stable ammonium...
    4 KB (161 words) - 12:31, 1 June 2024
  • enantioselective analysis. Chiral analysis includes all analytical procedures focused on the characterization of the properties of chiral drugs. Chiral analysis is usually...
    63 KB (6,792 words) - 22:07, 2 December 2023
  • Viedma ripening (category Chirality)
    technique to separate enantiomers of chiral molecules in the pharmaceutical and fine chemical industries (chiral resolution). The exact interplay of the mechanisms...
    8 KB (899 words) - 12:52, 5 January 2024
  • Thumbnail for Stereochemistry
    Stereochemistry. Alkane stereochemistry Chiral resolution, which often involves crystallization Chirality (chemistry) (R/S, d/l) Chiral switch Skeletal formula#Stereochemistry...
    13 KB (1,461 words) - 11:17, 3 November 2024
  • Thumbnail for Diastereomer
    knowledge is harnessed in chiral synthesis to separate a mixture of enantiomers. This is the principle behind chiral resolution. After preparing the diastereomers...
    9 KB (1,089 words) - 10:27, 24 July 2024
  • Planar chirality, also known as 2D chirality, is the special case of chirality for two dimensions. Most fundamentally, planar chirality is a mathematical...
    9 KB (1,062 words) - 05:36, 27 December 2023
  • Thumbnail for Menthol
    isolated by fractional distillation. The enantiomers are separated by chiral resolution in reaction with methyl benzoate, selective crystallisation followed...
    31 KB (2,946 words) - 11:15, 2 November 2024
  • Thumbnail for Malic acid
    capacity was 5,000 tons per year. The enantiomers may be separated by chiral resolution of the racemic mixture. S-Malic acid is obtained by fermentation of...
    17 KB (1,322 words) - 04:54, 16 July 2024
  • Thumbnail for Amphetamine
    salt which is fractionally crystallized to yield dextroamphetamine. Chiral resolution remains the most economical method for obtaining optically pure amphetamine...
    274 KB (28,856 words) - 03:42, 2 November 2024
  • provided by Prelog a year earlier to quinotoxine (enantiopure after chiral resolution) that is described. Woodward and Doering argue that Rabe in 1918 already...
    18 KB (2,207 words) - 20:44, 4 October 2024
  • Thumbnail for Enantiomer
    absence of an effective enantiomeric environment (precursor, chiral catalyst, or kinetic resolution), separation of a racemic mixture into its enantiomeric...
    24 KB (2,632 words) - 01:30, 4 November 2024
  • otherwise be chiral due to a nitrogen stereocenter, nitrogen inversion provides a low energy pathway for racemization, usually making chiral resolution impossible...
    9 KB (918 words) - 15:34, 13 February 2024
  • Thumbnail for Chiral auxiliary
    In stereochemistry, a chiral auxiliary is a stereogenic group or unit that is temporarily incorporated into an organic compound in order to control the...
    34 KB (3,692 words) - 20:40, 22 July 2024
  • Thumbnail for Zeise's salt
    (PtCl2(C2H4)(PhCH(NH2)Me) is a chiral derivative of Zeise's salt that is used for the chiral resolution of alkenes. Aldrich datasheet "C&L Inventory"...
    10 KB (842 words) - 21:51, 1 November 2024
  • Thumbnail for Crystallization
    amounts of energy to be supplied to the system. Abnormal grain growth Chiral resolution by crystallization Crystal habit Crystal structure Crystallite Fractional...
    31 KB (3,939 words) - 20:39, 1 November 2024
  • Thumbnail for Chiral thin-layer chromatography
    use either a chiral stationary phase or a chiral additive in the mobile phase. The chiral stationary phase can be prepared by mixing chirally pure reagents...
    3 KB (328 words) - 21:13, 25 February 2024
  • Thumbnail for Cholesterol total synthesis
    the allyl alcohol 27. Chiral resolution of this racemic compound with digitonin produced chiral 28 and on Oppenauer oxidation chiral 29. Hydrogenation (Adams'...
    9 KB (1,098 words) - 12:52, 14 April 2023
  • Homochirality is a uniformity of chirality, or handedness. Objects are chiral when they cannot be superposed on their mirror images. For example, the left...
    40 KB (5,098 words) - 21:14, 1 October 2024
  • Thumbnail for Brucine
    reactivity toward chromic acid. Since brucine is a large chiral molecule, it has been used in chiral resolution. Fisher first reported its use as a resolving agent...
    11 KB (999 words) - 18:26, 8 July 2024
  • Thumbnail for Tremetone
    the final product was a racemate that would not suitably undergo chiral resolution. This prevented isolation of the natural levorotary enantiomer of...
    5 KB (435 words) - 07:49, 12 April 2024
  • Thumbnail for 1,2-Diaminopropane
    of the ammonium salt with sodium hydroxide. Alternate reagents for chiral resolution include N-p-toluenesulfonylaspartic acid, N-benzenesulfonylaspartic...
    5 KB (288 words) - 17:42, 6 July 2024