Chromatin is a complex of DNA and protein found in eukaryotic cells. The primary function is to package long DNA molecules into more compact, denser structures...
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Chromatin remodeling is the dynamic modification of chromatin architecture to allow access of condensed genomic DNA to the regulatory transcription machinery...
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Chromatin immunoprecipitation (ChIP) is a type of immunoprecipitation experimental technique used to investigate the interaction between proteins and...
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salt-and-pepper chromatin, also salt-and-pepper nuclei and stippled chromatin, refers to cell nuclei that demonstrate granular chromatin (on light microscopy)...
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Bivalent chromatin are segments of DNA, bound to histone proteins, that have both repressing and activating epigenetic regulators in the same region....
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A chromatin variant (also known as an epigenetic lesion, epimutation or epigenetic alteration) corresponds to a section of the genome that differs in...
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Chromosome (section Interphase chromatin)
term 'chromatin', which was introduced by Walther Flemming. Some of the early karyological terms have become outdated. For example, 'chromatin' (Flemming...
63 KB (6,601 words) - 10:54, 23 December 2024
Euchromatin (redirect from Open chromatin)
Euchromatin (also called "open chromatin") is a lightly packed form of chromatin (DNA, RNA, and protein) that is enriched in genes, and is often (but...
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An active chromatin sequence (ACS) is a region of DNA in a eukaryotic chromosome in which histone modifications such as acetylation lead to exposure of...
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wrapped around a spool. The nucleosome is the fundamental subunit of chromatin. Each nucleosome is composed of a little less than two turns of DNA wrapped...
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Barr body (redirect from Chromatin body)
A Barr body (named after discoverer Murray Barr) or X-chromatin is an inactive X chromosome. In species with XY sex-determination (including humans),...
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Epigenetics & Chromatin is a peer-reviewed open access scientific journal published by BioMed Central that covers the biology of epigenetics and chromatin. Epigenetics...
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ISWI (Imitation SWItch) is one of the five major DNA chromatin remodeling complex types, or subfamilies, found in most eukaryotic organisms. ISWI remodeling...
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Topologically associating domain (redirect from Topological chromatin domain)
extrudes chromatin to progressively grow a loop. Chromatin on both sides of the cohesin complex is extruded until cohesin encounters a chromatin-bound CTCF...
32 KB (3,426 words) - 03:04, 18 November 2024
Hi-C is a high-throughput genomic and epigenomic technique to capture chromatin conformation (3C). In general, Hi-C is considered as a derivative of a...
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Insulator (genetics) (redirect from Chromatin insulation)
enhancer-blocker Similar mechanism of action for enhancer-blocking insulators; chromatin loop domains are formed in the nucleus that separates the enhancer and...
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Prophase (redirect from Chromatin condensation)
prophase. The main occurrences in prophase are the condensation of the chromatin reticulum and the disappearance of the nucleolus. Microscopy can be used...
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RNA polymerase II (redirect from RNA polymerase control by chromatin structure)
influences whether the histones of transcribed nucleosomes are evicted from chromatin, or reinserted behind the transcribing polymerase. RNA polymerase II is...
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Chromatin bridge is a mitotic occurrence that forms when telomeres of sister chromatids fuse together and fail to completely segregate into their respective...
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Theodor Boveri (redirect from Chromatin diminution)
hypothesis regarding cellular processes that cause cancer, and for describing chromatin diminution in nematodes. His brother was industrialist Walter Boveri....
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DNA-SCARS (short for DNA segments with chromatin alterations reinforcing senescence) are nuclear substructures with persistent DNA damage and DNA damage...
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Histone (section Chromatin regulation)
in turn are wrapped into 30-nanometer fibers that form tightly packed chromatin. Histones prevent DNA from becoming tangled and protect it from DNA damage...
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gradient of GTP-bound Ran is generated around the vicinity of mitotic chromatin. Glass beads coated with RCC1 induce microtubule nucleation and bipolar...
28 KB (3,300 words) - 12:32, 30 September 2024
Epigenetics (section Chromatin Immunoprecipitation)
for chromatin-modifying enzymes (or transcription machinery as well). This chromatin remodeler can then cause changes to the state of the chromatin. Indeed...
160 KB (18,278 words) - 05:12, 30 December 2024
Structure of Chromatin) is a member of the ATP-dependent chromatin remodeler family. The activity of the RSC complex allows for chromatin to be remodeled...
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Chromatin assembly factor-1 (CAF-1) is a protein complex — including Chaf1a (p150), Chaf1b (p60), and p48 subunits in humans, or Cac1, Cac2, and Cac3...
10 KB (1,163 words) - 03:34, 25 July 2024
Sperm Chromatin Structure Assay (SCSA) is a diagnostic approach that detects sperm abnormality with a large extent of DNA fragmentation. First described...
31 KB (3,564 words) - 21:31, 14 December 2024
The solenoid structure of chromatin is a model for the structure of the 30 nm fibre. It is a secondary chromatin structure which helps to package eukaryotic...
17 KB (2,057 words) - 07:03, 19 May 2024
Chromatin Interaction Analysis by Paired-End Tag Sequencing (ChIA-PET or ChIA-PETS) is a technique that incorporates chromatin immunoprecipitation (ChIP)-based...
26 KB (2,925 words) - 23:50, 20 October 2024
for Transposase-Accessible Chromatin using sequencing) is a technique used in molecular biology to assess genome-wide chromatin accessibility. In 2013, the...
16 KB (1,730 words) - 02:02, 3 December 2024