Delta-like 3 (Drosophila), also known as DLL3, is a protein which in humans is encoded by the DLL3 gene. Two transcript variants encoding distinct isoforms...

Govindan R, Boyer M, et al. (June 2023). "Tarlatamab, a First-in-Class DLL3-Targeted Bispecific T-Cell Engager, in Recurrent Small-Cell Lung Cancer:...

homologues of three genes associated to the mouse segmentation clock, (MESP2, DLL3 and LFNG), have been shown to be mutated in cases of congenital scoliosis...

(Rova-T) is an experimental antibody-drug conjugate targeting the protein DLL3 on tumor cells. It was originally developed by Stemcentrx and was purchased...

clock and wavefront model, forms the boundaries of the somites. DLL1 and DLL3 are Notch ligands, mutations of which cause various defects. Notch regulates...

HGNC:2907 P80370 4319 DLK2 HGNC:21113 Q6UY11 4320 DLL1 HGNC:2908 O00548 4321 DLL3 HGNC:2909 Q9NYJ7 4322 DLL4 HGNC:2910 Q9NR61 4323 DLST HGNC:2911 P36957 4324...

antigen receptor (CAR-T) therapies, that go after delta-like ligand protein 3 (DLL3) including large cell neuroendocrine carcinoma candidate LB2102 for $100 million...

that is being researched to treat advanced cancer patients associated with DLL3 expression (delta-like ligand 3), an inherent small cell lung cancer (SCLC)...

antigen receptor (CAR-T) therapies, that go after delta-like ligand protein 3 (DLL3) including large cell neuroendocrine carcinoma candidate LB2102. Novartis...

root plate-specific spondin 3 cancer Rovalpituzumab tesirine mab humanized DLL3 small cell lung cancer Rovelizumab LeukArrest mab humanized CD11, CD18 Y...

coordinate key steps in this process. In mice, mutations in Notch1, Dll1 or Dll3, Lfng, or Hes7 result in abnormal somite formation. Similarly, in humans...

disorder, spondylocostal dysostosis, caused by mutations in delta-like 3 (DLL3), and he contributed to subsequent research identifying mutations in the...

The Notch pathway, through transcriptional activation of Delta ligand (see DLL3). MET mediates a complex program known as invasive growth. Activation of...

Type OMIM Gene Locus SCDO1 277300 DLL3 19q13 SCDO2 608681 MESP2 15q26.1 SCDO3 609813 LFNG 7p22 SCDO4 122600 GDF6 8q22.1...

CNTNAP3; CNTNAP4; CNTNAP5; COMP; COX-2; CRB1; CRB2; CSPG3; CUBN; DLK1; DLL1; DLL3; DLL4; DNER; EDIL3; EGF; EGFL11; EGFL8; EGFL9; EGFLAM; EPGN; EREG; F7; F9;...

منتديات دلع" [Rumour: singer Angham is banned from singing in Kuwait]. vb.dll3.com (in Arabic). Archived from the original on 26 May 2007. Retrieved 31...

609813; LFNG Spondylocostal dysostosis, autosomal recessive, 1; 277300; DLL3 Spondylocostal dystostosis 4, autosomal dominant; 122600; GDF6 Spondyloepimetaphyseal...