Estrogen receptor alpha (ERα), also known as NR3A1 (nuclear receptor subfamily 3, group A, member 1), is one of two main types of estrogen receptor, a...
58 KB (6,133 words) - 05:31, 13 July 2024
nuclear estrogen receptors (ERα and ERβ), which are members of the nuclear receptor family of intracellular receptors, and membrane estrogen receptors (mERs)...
35 KB (3,820 words) - 04:04, 5 July 2024
Estrogen-related receptor alpha (ERRα), also known as NR3B1 (nuclear receptor subfamily 3, group B, member 1), is a nuclear receptor that in humans is...
17 KB (1,995 words) - 21:24, 29 March 2024
Estrogen receptor beta (ERβ) also known as NR3A2 (nuclear receptor subfamily 3, group A, member 2) is one of two main types of estrogen receptor—a nuclear...
39 KB (4,522 words) - 20:36, 15 November 2023
caused by a defective estrogen receptor (ER) – specifically, the estrogen receptor alpha (ERα) – that results in an inability of estrogen to mediate its biological...
34 KB (3,802 words) - 00:18, 4 January 2024
Membrane estrogen receptors (mERs) are a group of receptors which bind estrogen. Unlike nuclear estrogen receptors, which mediate their effects via slower...
19 KB (1,985 words) - 03:22, 24 May 2024
of a selective inverse agonist for the orphan nuclear receptor estrogen-related receptor alpha". Journal of Medicinal Chemistry. 47 (23): 5593–6. doi:10...
74 KB (6,675 words) - 18:09, 20 June 2024
they bind to and activate estrogen receptors (ERs) which in turn modulate the expression of many genes. Additionally, estrogens bind to and activate rapid-signaling...
73 KB (7,781 words) - 16:34, 17 June 2024
Estrogen-related receptor beta (ERR-β), also known as ESRRB or NR3B2 (nuclear receptor subfamily 3, group B, member 2), is a nuclear receptor that in...
7 KB (800 words) - 19:11, 27 March 2024
estrogen receptor (ER): estrogen receptor alpha (ERα), and estrogen receptor beta (ER-β), also known as NR3A2. Both are nuclear receptors activated by the sex...
10 KB (1,332 words) - 19:38, 30 June 2024
Androgen receptors Calcitriol receptors Corticotropin-releasing hormone receptor 1 Corticotropin releasing hormone receptor 2 Estrogen receptors Follicle-stimulating...
17 KB (1,999 words) - 10:03, 27 December 2023
Cardenas J, Podvinec M, Oakeley EJ, Kralli A (April 2004). "The estrogen-related receptor alpha (ERRalpha) functions in PPARgamma coactivator 1alpha (PGC-1alpha)-induced...
11 KB (1,175 words) - 13:05, 3 December 2023
Selective estrogen receptor modulators (SERMs), also known as estrogen receptor agonist/antagonists (ERAAs), are a class of drugs that act on estrogen receptors...
55 KB (6,377 words) - 07:35, 22 July 2024
alpha, Estrogen receptor beta, Glucocorticoid receptor, IKBKG, IKK2, Peroxisome proliferator-activated receptor gamma, and Retinoid X receptor alpha. GRCh38:...
21 KB (2,438 words) - 21:40, 11 July 2024
DDX17, DDX5 and Estrogen receptor alpha, Glucocorticoid receptor, NFKB1, PCAF, PPARGC1A, Peroxisome proliferator-activated receptor alpha, SNW1, STAT3,...
15 KB (1,725 words) - 17:17, 1 July 2024
HI (January 2000). "The aryl hydrocarbon receptor interacts with estrogen receptor alpha and orphan receptors COUP-TFI and ERRalpha1". Archives of Biochemistry...
52 KB (5,968 words) - 15:15, 4 June 2024
agonists and alpha-2 (α2) agonists, which are used to treat high blood pressure and asthma, for example. Many cells have these receptors, and the binding...
33 KB (2,982 words) - 15:38, 5 June 2024
study involved estrogen receptors and differential splicing. The article entitled, "Alternative splicing of the human estrogen receptor alpha primary transcript:...
23 KB (3,023 words) - 12:36, 22 February 2024
factors on mammary gland development and differentiation in the estrogen receptor-alpha knockout (ERKO) mouse". Breast Cancer Res. Treat. 79 (2): 161–73...
59 KB (6,495 words) - 08:42, 1 July 2024
alpha-1 (α1) adrenergic receptors are G protein-coupled receptors (GPCRs) associated with the Gq heterotrimeric G protein. α1-adrenergic receptors are...
16 KB (1,528 words) - 10:28, 23 June 2024
be regulated by estrogen. It has been reported that there are kisspeptin-producing neurons that also express estrogen receptor alpha. GnRH is found in...
27 KB (3,150 words) - 08:47, 11 April 2024
Etacstil (category Selective estrogen receptor degraders)
selective estrogen receptor modulator (SERM) and selective estrogen receptor degrader (SERD) that was developed for the treatment of estrogen receptor-positive...
8 KB (695 words) - 07:29, 24 May 2024
factors on mammary gland development and differentiation in the estrogen receptor-alpha knockout (ERKO) mouse". Breast Cancer Research and Treatment. 79...
60 KB (6,879 words) - 14:26, 16 July 2024
For example, cadmium can bind to the estrogen receptor alpha, and affect signal transduction along the estrogen and MAPK signaling pathways at low doses...
66 KB (7,332 words) - 18:33, 7 July 2024
proliferation and apoptosis. It also decreases the expression of estrogen receptor alpha in ER-positive breast cancer. Polyamine oxidase Polyamines in plant...
15 KB (1,645 words) - 14:28, 22 June 2024
studied steroid hormone receptors are members of the nuclear receptor subfamily 3 (NR3) that include receptors for estrogen (group NR3A) and 3-ketosteroids...
23 KB (2,796 words) - 19:08, 19 February 2024
shown to interact with Androgen receptor, Estrogen receptor alpha, and Hepatocyte nuclear factor 4 alpha. Testicular receptor GRCh38: Ensembl release 89:...
9 KB (1,137 words) - 05:07, 13 October 2022
et al. (2010). "Estrogen-induced sexual incentive motivation, proceptivity and receptivity depend on a functional estrogen receptor [alpha] in the ventromedial...
48 KB (5,709 words) - 11:12, 22 June 2024
affinities for the estrogen receptors. Its relative binding affinities (RBAs) for estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ) are both...
4 KB (251 words) - 09:43, 18 August 2023
Elacestrant (category Selective estrogen receptor degraders)
the estrogen receptors, the biological targets of endogenous estrogens like estradiol. It is specifically an antagonist of the estrogen receptor alpha (ERα)...
13 KB (946 words) - 06:19, 18 December 2023