In pharmacology, the fibrates are a class of amphipathic carboxylic acids and esters. They are derivatives of fibric acid (phenoxyisobutyric acid). They...
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[citation needed] Treatment include diet control, fibrates and niacins. Statins are not better than fibrates when lowering triglyceride levels.[citation needed]...
37 KB (3,520 words) - 14:53, 19 February 2024
under the brand names Tricor, Fenobrat etc.), is an oral medication of the fibrate class used to treat abnormal blood lipid levels. It is less commonly used...
26 KB (2,461 words) - 13:52, 11 July 2024
would increase the risk of pancreatitis is treated with a drug from the fibrate class. Niacin and omega-3 fatty acids as well as drugs from the statin...
18 KB (1,673 words) - 18:21, 28 July 2024
these four types of classifications form a hierarchy. For example, the fibrates are a chemical class of drugs (amphipathic carboxylic acids) that share...
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Bezafibrate (marketed as Bezalip and various other brand names) is a fibrate drug used as a lipid-lowering agent to treat hyperlipidaemia. It helps to...
8 KB (688 words) - 09:07, 23 September 2023
would increase the risk of pancreatitis is treated with a drug from the fibrate class. Niacin and omega-3 fatty acids as well as drugs from the statin...
130 KB (15,210 words) - 17:48, 3 August 2024
saturated, after which VLDL levels elevate. Both conditions are treated with fibrate drugs, which act on the peroxisome proliferator-activated receptors (PPARs)...
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13-hydroxyoctadecadienoic acid, a linoleic acid metabolite. Synthetic ligands include the fibrate drugs, which are used to treat hyperlipidemia, and a diverse set of insecticides...
22 KB (2,563 words) - 18:52, 10 July 2024
wood pulp from a supplier in Mumbai, and the machines would grind, de-fibrate, press and sterilize the pads under ultraviolet light before packaging...
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Gemfibrozil (category Fibrates)
in pregnancy and breastfeeding is of unclear safety. It belongs to the fibrates group of medications and works by decreasing the breakdown of lipids in...
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Ciprofibrate is a fibrate that was developed as a lipid-lowering agent. It was patented in 1972 and approved for medical use in 1985. Fischer J, Ganellin...
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Clinofibrate (INN) (trade name Lipoclin) is a fibrate and a derivative of Bisphenol Z. The reaction between cyclohexanone and phenol gives Bisphenol Z...
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simvastatin) have been evaluated in clinical trials in combination with fibrates to manage dyslipidemia in patients who also have type 2 diabetes, and a...
100 KB (9,421 words) - 00:58, 12 July 2024
increase the risk of rhabdomyolysis. The most important ones are: Statins and fibrates, both used for elevated cholesterol, especially in combination; cerivastatin...
49 KB (4,816 words) - 10:13, 14 May 2024
greater risk of cardiovascular disease over the next ten years. Niacin, fibrates and CETP Inhibitors, while they may increase HDL cholesterol do not affect...
137 KB (14,460 words) - 07:12, 12 August 2024
Dyslipidemia (section Fibrates)
they improved cardiovascular outcomes. The cholesterol lowering effect of fibrates is due to their ability to activate a nuclear receptor called peroxisome...
30 KB (2,961 words) - 13:47, 30 May 2024
sequestrants (cholestyramine or colestipol), nicotinic acid preparations or fibrates. Control of other risk factors for cardiovascular disease is required,...
48 KB (5,456 words) - 18:52, 29 May 2024
Polysiphonia fibrata (redirect from Polysiphonia fibrate)
and finely branched marine alga in the Rhodophyta. The branches of P. fibrate are numerous and much interwoven forming tufts up to 20 cm long. They are...
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could trigger dendritic activation. PPARα (alpha) is the main target of fibrate drugs, a class of amphipathic carboxylic acids (clofibrate, gemfibrozil...
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mortality, despite lowered cholesterol levels. Other developed and tested fibrates, e.g. fenofibric acid have had a better track record and are primarily...
54 KB (6,021 words) - 21:25, 31 July 2024
observed with high-intensity statin therapy. They have less effect than the fibrates or niacin in reducing triglycerides and raising HDL-cholesterol ("good...
128 KB (12,866 words) - 21:17, 6 June 2024
Viral Compression injury leading to crush syndrome Drug-related Commonly fibrates and statins Occasionally ACE inhibitors, cocaine, and some retro-viral...
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against sun damage. A 2005 review found tentative evidence that statin and fibrate medication may decrease the risk of melanoma. A 2006 review however did...
154 KB (16,076 words) - 04:50, 7 August 2024
often followed by one of various hypolipidemic agents, such as statins, fibrates, cholesterol absorption inhibitors, monoclonal antibody therapy (PCSK9...
80 KB (8,530 words) - 10:23, 11 August 2024
statin drugs are more increased after age 85. Fibrates are indicated for hypertriglyceridemia. Fibrates typically lower triglycerides by 20% to 50%. Level...
11 KB (1,251 words) - 17:11, 6 June 2024
Aluminium clofibrate (or alfibrate) is a fibrate. Clofibrate v t e...
2 KB (11 words) - 00:55, 24 January 2023
may have significant medication interactions with ciclosporin and with fibrates other than fenofibrate. Common adverse drug reactions (≥1% of patients)...
20 KB (1,819 words) - 11:14, 1 July 2024
dyslipidemia, which may present a risk for coronary artery disease. Statins and fibrates are generally used as lipid lowering therapy to treat patients with cholestatic...
112 KB (12,703 words) - 07:34, 10 August 2024
cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including...
92 KB (8,789 words) - 16:52, 1 July 2024