• Thumbnail for Fibrate
    In pharmacology, the fibrates are a class of amphipathic carboxylic acids and esters. They are derivatives of fibric acid (phenoxyisobutyric acid). They...
    10 KB (1,091 words) - 19:14, 28 August 2023
  • [citation needed] Treatment include diet control, fibrates and niacins. Statins are not better than fibrates when lowering triglyceride levels.[citation needed]...
    37 KB (3,520 words) - 14:53, 19 February 2024
  • Thumbnail for Fenofibrate
    under the brand names Tricor, Fenobrat etc.), is an oral medication of the fibrate class used to treat abnormal blood lipid levels. It is less commonly used...
    26 KB (2,461 words) - 13:52, 11 July 2024
  • Thumbnail for Hypertriglyceridemia
    would increase the risk of pancreatitis is treated with a drug from the fibrate class. Niacin and omega-3 fatty acids as well as drugs from the statin...
    18 KB (1,673 words) - 18:21, 28 July 2024
  • these four types of classifications form a hierarchy. For example, the fibrates are a chemical class of drugs (amphipathic carboxylic acids) that share...
    10 KB (1,020 words) - 14:12, 14 August 2024
  • Thumbnail for Bezafibrate
    Bezafibrate (marketed as Bezalip and various other brand names) is a fibrate drug used as a lipid-lowering agent to treat hyperlipidaemia. It helps to...
    8 KB (688 words) - 09:07, 23 September 2023
  • Thumbnail for Fat
    would increase the risk of pancreatitis is treated with a drug from the fibrate class. Niacin and omega-3 fatty acids as well as drugs from the statin...
    130 KB (15,210 words) - 17:48, 3 August 2024
  • Thumbnail for Combined hyperlipidemia
    saturated, after which VLDL levels elevate. Both conditions are treated with fibrate drugs, which act on the peroxisome proliferator-activated receptors (PPARs)...
    4 KB (359 words) - 20:27, 9 February 2023
  • Thumbnail for Peroxisome proliferator-activated receptor alpha
    13-hydroxyoctadecadienoic acid, a linoleic acid metabolite. Synthetic ligands include the fibrate drugs, which are used to treat hyperlipidemia, and a diverse set of insecticides...
    22 KB (2,563 words) - 18:52, 10 July 2024
  • Thumbnail for Arunachalam Muruganantham
    wood pulp from a supplier in Mumbai, and the machines would grind, de-fibrate, press and sterilize the pads under ultraviolet light before packaging...
    19 KB (1,401 words) - 11:54, 11 August 2024
  • Thumbnail for Gemfibrozil
    Gemfibrozil (category Fibrates)
    in pregnancy and breastfeeding is of unclear safety. It belongs to the fibrates group of medications and works by decreasing the breakdown of lipids in...
    12 KB (950 words) - 06:13, 1 April 2024
  • Thumbnail for Ciprofibrate
    Ciprofibrate is a fibrate that was developed as a lipid-lowering agent. It was patented in 1972 and approved for medical use in 1985. Fischer J, Ganellin...
    2 KB (43 words) - 00:32, 24 January 2023
  • Thumbnail for Clinofibrate
    Clinofibrate (INN) (trade name Lipoclin) is a fibrate and a derivative of Bisphenol Z. The reaction between cyclohexanone and phenol gives Bisphenol Z...
    4 KB (154 words) - 14:20, 29 June 2024
  • Thumbnail for Atorvastatin
    simvastatin) have been evaluated in clinical trials in combination with fibrates to manage dyslipidemia in patients who also have type 2 diabetes, and a...
    100 KB (9,421 words) - 00:58, 12 July 2024
  • Thumbnail for Rhabdomyolysis
    increase the risk of rhabdomyolysis. The most important ones are: Statins and fibrates, both used for elevated cholesterol, especially in combination; cerivastatin...
    49 KB (4,816 words) - 10:13, 14 May 2024
  • Thumbnail for Cardiovascular disease
    greater risk of cardiovascular disease over the next ten years. Niacin, fibrates and CETP Inhibitors, while they may increase HDL cholesterol do not affect...
    137 KB (14,460 words) - 07:12, 12 August 2024
  • they improved cardiovascular outcomes. The cholesterol lowering effect of fibrates is due to their ability to activate a nuclear receptor called peroxisome...
    30 KB (2,961 words) - 13:47, 30 May 2024
  • Thumbnail for Familial hypercholesterolemia
    sequestrants (cholestyramine or colestipol), nicotinic acid preparations or fibrates. Control of other risk factors for cardiovascular disease is required,...
    48 KB (5,456 words) - 18:52, 29 May 2024
  • and finely branched marine alga in the Rhodophyta. The branches of P. fibrate are numerous and much interwoven forming tufts up to 20 cm long. They are...
    2 KB (233 words) - 18:15, 10 March 2021
  • Thumbnail for PPAR agonist
    could trigger dendritic activation. PPARα (alpha) is the main target of fibrate drugs, a class of amphipathic carboxylic acids (clofibrate, gemfibrozil...
    9 KB (1,045 words) - 10:21, 18 July 2024
  • Thumbnail for Low-density lipoprotein
    mortality, despite lowered cholesterol levels. Other developed and tested fibrates, e.g. fenofibric acid have had a better track record and are primarily...
    54 KB (6,021 words) - 21:25, 31 July 2024
  • Thumbnail for Statin
    observed with high-intensity statin therapy. They have less effect than the fibrates or niacin in reducing triglycerides and raising HDL-cholesterol ("good...
    128 KB (12,866 words) - 21:17, 6 June 2024
  • Thumbnail for Myalgia
    Viral Compression injury leading to crush syndrome Drug-related Commonly fibrates and statins Occasionally ACE inhibitors, cocaine, and some retro-viral...
    9 KB (677 words) - 21:57, 19 July 2024
  • Thumbnail for Melanoma
    against sun damage. A 2005 review found tentative evidence that statin and fibrate medication may decrease the risk of melanoma. A 2006 review however did...
    154 KB (16,076 words) - 04:50, 7 August 2024
  • Thumbnail for Cholesterol
    often followed by one of various hypolipidemic agents, such as statins, fibrates, cholesterol absorption inhibitors, monoclonal antibody therapy (PCSK9...
    80 KB (8,530 words) - 10:23, 11 August 2024
  • statin drugs are more increased after age 85. Fibrates are indicated for hypertriglyceridemia. Fibrates typically lower triglycerides by 20% to 50%. Level...
    11 KB (1,251 words) - 17:11, 6 June 2024
  • Aluminium clofibrate (or alfibrate) is a fibrate. Clofibrate v t e...
    2 KB (11 words) - 00:55, 24 January 2023
  • Thumbnail for Ezetimibe
    may have significant medication interactions with ciclosporin and with fibrates other than fenofibrate. Common adverse drug reactions (≥1% of patients)...
    20 KB (1,819 words) - 11:14, 1 July 2024
  • Thumbnail for Cholestasis
    dyslipidemia, which may present a risk for coronary artery disease. Statins and fibrates are generally used as lipid lowering therapy to treat patients with cholestatic...
    112 KB (12,703 words) - 07:34, 10 August 2024
  • Thumbnail for Niacin
    cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including...
    92 KB (8,789 words) - 16:52, 1 July 2024