• Thumbnail for Fibroblast growth factor receptor 1
    Fibroblast growth factor receptor 1 (FGFR1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome...
    44 KB (5,001 words) - 17:06, 4 January 2024
  • The fibroblast growth factor receptors (FGFR) are, as their name implies, receptors that bind to members of the fibroblast growth factor (FGF) family of...
    8 KB (827 words) - 22:08, 3 December 2023
  • fibroblast growth factor receptors (FGFRs). FGF1 is also known as acidic fibroblast growth factor, and FGF2 is also known as basic fibroblast growth factor...
    25 KB (3,123 words) - 20:10, 26 April 2024
  • Thumbnail for Basic fibroblast growth factor
    via specific fibroblast growth factor receptor (FGFR) proteins, themselves a family of closely related molecules. Fibroblast growth factor protein was...
    22 KB (2,693 words) - 04:46, 19 April 2024
  • Thumbnail for Fibroblast growth factor receptor 3
    Fibroblast growth factor receptor 3 is a protein that in humans is encoded by the FGFR3 gene. FGFR3 has also been designated as CD333 (cluster of differentiation...
    17 KB (1,955 words) - 06:59, 15 April 2024
  • Thumbnail for Fibroblast growth factor 23
    Fibroblast growth factor 23 (FGF23) is a protein and member of the fibroblast growth factor (FGF) family which participates in the regulation of phosphate...
    17 KB (1,854 words) - 21:05, 6 June 2024
  • Thumbnail for Fibroblast growth factor receptor 2
    Fibroblast growth factor receptor 2 (FGFR2) also known as CD332 (cluster of differentiation 332) is a protein that in humans is encoded by the FGFR2 gene...
    14 KB (1,748 words) - 14:34, 11 December 2023
  • growth factor (FGF) Fibroblast growth factor 1(FGF1) Fibroblast growth factor 2(FGF2) Fibroblast growth factor 3(FGF3) Fibroblast growth factor 4(FGF4)...
    10 KB (1,131 words) - 19:14, 31 March 2024
  • Thumbnail for Fibroblast growth factor receptor 4
    Fibroblast growth factor receptor 4 is a protein that in humans is encoded by the FGFR4 gene. FGFR4 has also been designated as CD334 (cluster of differentiation...
    10 KB (1,289 words) - 15:12, 18 August 2022
  • Thumbnail for Epidermal growth factor receptor
    epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth factor family...
    60 KB (6,879 words) - 09:57, 15 January 2024
  • Thumbnail for Fibroblast growth factor 21
    Fibroblast growth factor 21 is a protein that in mammals is encoded by the FGF21 gene. The protein encoded by this gene is a member of the fibroblast...
    24 KB (3,036 words) - 16:02, 18 May 2024
  • Thumbnail for Pfeiffer syndrome
    Pfeiffer syndrome (category Cell surface receptor deficiencies)
    caused by mutations in the fibroblast growth factor receptors FGFR1 and FGFR2. The syndrome is grouped into three types: type 1 (classic Pfeiffer syndrome)...
    14 KB (1,444 words) - 13:44, 3 July 2024
  • Thumbnail for Insulin-like growth factor 1
    Insulin-like growth factor 1 (IGF-1), also called somatomedin C, is a hormone similar in molecular structure to insulin which plays an important role in...
    36 KB (4,822 words) - 06:03, 26 June 2024
  • Thumbnail for Fibroblast growth factor receptor-like 1
    Fibroblast growth factor receptor-like 1 is a protein that in humans is encoded by the FGFRL1 gene. The protein encoded by this gene is a member of the...
    6 KB (842 words) - 01:10, 27 January 2024
  • Thumbnail for Receptor tyrosine kinase
    Receptor tyrosine kinases (RTKs) are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones. Of the 90...
    28 KB (3,078 words) - 07:46, 3 June 2024
  • Thumbnail for Platelet-derived growth factor
    fibroblast growth factor (FGF) activates a signaling pathway that positively regulates the PDGF receptors in OPCs. PDGF was one of the first growth factors...
    24 KB (2,877 words) - 10:08, 2 June 2024
  • cell culture system, rat kidney fibroblasts. Application of the transforming growth factors to normal rat kidney fibroblasts induces the cultured cells to...
    6 KB (596 words) - 05:15, 1 January 2024
  • epithelium. KGF is a small signaling molecule that binds to fibroblast growth factor receptor 2b (FGFR2b). For signalling to occur, a dimer is required...
    2 KB (182 words) - 00:56, 11 June 2023
  • Thumbnail for Fibroblast growth factor 8
    Fibroblast growth factor 8 (FGF-8) is a protein that in humans is encoded by the FGF8 gene. The protein encoded by this gene is a member of the fibroblast...
    17 KB (2,175 words) - 03:31, 24 December 2023
  • insulin-like growth factor-2 (IGF-2), transforming growth factor beta (TGF-β), fibroblast growth factors (FGFs), platelet-derived growth factor (PDGF), parathyroid...
    17 KB (2,024 words) - 10:43, 27 June 2024
  • Thumbnail for Low-affinity nerve growth factor receptor
    nerve growth factor. p75NTR is a neurotrophic factor receptor. Neurotrophic factor receptors bind Neurotrophins including Nerve growth factor, Neurotrophin-3...
    37 KB (4,235 words) - 13:48, 29 June 2024
  • Thumbnail for Hepatocyte growth factor
    signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by platelets, and mesenchymal cells and acts as...
    23 KB (2,711 words) - 10:05, 2 June 2024
  • Thumbnail for FGF1
    Fibroblast growth factor 1, (FGF-1) also known as acidic fibroblast growth factor (aFGF), is a growth factor and signaling protein encoded by the FGF1...
    20 KB (2,307 words) - 17:41, 12 February 2024
  • enzymatic activity include: Receptor tyrosine kinase, as in fibroblast growth factor receptor. Most enzyme-linked receptors are of this type. Serine/threonine-specific...
    7 KB (350 words) - 19:02, 13 March 2024
  • Fibroblast growth factor receptor oncogene partner 2 (FGFR1OP2) was identified in a study on myeloproliferative syndrome (EMS). The study aimed to identify...
    19 KB (1,126 words) - 18:38, 6 February 2024
  • Thumbnail for Transforming growth factor beta
    other factors to form a serine/threonine kinase complex that binds to TGF-β receptors. TGF-β receptors are composed of both type 1 and type 2 receptor subunits...
    70 KB (8,485 words) - 08:12, 19 May 2024
  • Thumbnail for Interleukin 4
    factors including epidermal growth factor receptor, FGFR-1 (fibroblast growth factor receptor 1), TfR (transferrin receptor), IL-13R. Most human meningiomas...
    19 KB (2,293 words) - 11:05, 8 March 2024
  • Thumbnail for Platelet-derived growth factor receptor A
    Platelet-derived growth factor receptor A, also termed CD140a, is a receptor located on the surface of a wide range of cell types. The protein is encoded...
    29 KB (3,354 words) - 17:01, 9 December 2023
  • This article is about the role of Fibroblast Growth Factor Signaling in Mesoderm Formation. Mesoderm formation is a complex developmental process involving...
    10 KB (1,399 words) - 19:03, 1 April 2023
  • glia maturation factor, insulin, insulin-like growth factor 1 (IGF-1), vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF), platelet-derived...
    16 KB (1,784 words) - 04:08, 6 January 2024