Aggarwal, A. K.; Wah, D. A.; Hirsch, J. A.; Dorner, L. F.; Schildkraut, I. (1997). "Structure of the multimodular endonuclease Fok1 bound to DNA". Nature...

Initial TALEN studies used the wild-type FokI cleavage domain, but some subsequent TALEN studies also used FokI cleavage domain variants with mutations...

double-strand breaks (DSBs) in target DNA by the restriction endonucleases (FokI and Cas), and the repair of DSBs through homology-directed recombination...

restriction endonucleases, such as DpnI, are able to recognize and cut methylated DNA. Type IIS restriction endonucleases (e.g. FokI) cleave DNA at a defined distance...

Foki (Russian: Фоки) is a rural locality (a selo) and the administrative center of Fokinskoye Rural Settlement, Chaykovsky, Perm Krai, Russia. The population...

non-specific cleavage domain from the type IIs restriction endonuclease FokI is typically used as the cleavage domain in ZFNs. This cleavage domain must...

Timothy Fok Tsun-ting (born 14 February 1946), GBS, JP, the eldest son of Henry Fok, is the President of the Hong Kong Football Association. He formerly...

also requires transition molecules as well as the FokI enzyme to be present. The requirement for the FokI enzyme limits application in vivo, at least for...

made þaim kaiba i bormoþa huni A2 huwaʀ ob kam harie a hit lat A3 gotna fiskʀ oʀ firnauim suwimade foki af (f)a(nwan)ga lande B a(i a)u is urki C1 ni...

okeanokoites is the original source for the type IIs restriction endonuclease FokI, used in Zinc finger nucleases and TALENs. Species who are a part of the...

are typically created through the fusion of Zinc-finger domains and the FokI nuclease domain. ZFNs have thus the ability to cleave DNA at target sites...

cleavage domain (usually the cleavage domain of FokI) to generate zinc finger nucleases. Such zinc finger-FokI fusions have become useful reagents for manipulating...

monomers in which each subunit contains a zinc domain and a FokI endonuclease domain. The FokI domains must dimerize for activities, thus narrowing target...

is the creation of artificial restriction enzymes created by linking the FokI DNA cleavage domain with an array of DNA binding proteins or zinc finger...

PMID 15458627. Bitinaite J, Wah DA, Aggarwal AK, Schildkraut I (September 1998). "FokI dimerization is required for DNA cleavage". Proceedings of the...

another nuclease enzyme from E. coli. FokI, a nuclease enzyme from Flavobacterium okeanokoites Schildkraut I, Banner CD, Rhodes CS, Parekh S (1984)....

and VDR association with progression to AIDS follows an additive model. FokI polymorphism is a risk factor for enveloped virus infection as revealed in...

subsequent infections. Hence these sequences play a key role in the antiviral (i.e. anti-phage) defense system of prokaryotes and provide a form of heritable...

1365-313X.1999.00526.x. PMID 10476082. Mandecki W, Bolling TJ (August 1988). "FokI method of gene synthesis". Gene. 68 (1): 101–7. doi:10.1016/0378-1119(88)90603-8...

dimerization-dependent FokI nuclease domains, used in ZFNs and TALENs, with the simplicity of CRISPR-cas9 has been developed. The FokI nuclease was originally...

REACH ROME QUARTER-FINALS". www.eurosport.com. Retrieved 19 December 2021. "Foki Sinks Ruud In Epic Five-Setter". www.atptour.com. 4 June 2021. Retrieved...

CRISPR-Gold - CRISPRa - CRISPRi Easi-CRISPR - FACE Enzyme Cas9 - FokI - EcoRI - PstI - SmaI HaeIII - Cas12a (Cpf1) - xCas9 Applications CAMERA - ICE - Genética...

2011). "TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain". Nucleic Acids Research. 39 (1): 359–72. doi:10.1093/nar/gkq704...

in human cells. CRISPR-Cas systems are separated into two classes: Class I, in which several Cas proteins associate with a crRNA to build a functional...

pluripotency in human and mouse cells providing an alternative method to iPS technology. In addition, large-scale activation screens could be used to...

PMID 8577732. Bitinaite J, Wah DA, Aggarwal AK, Schildkraut I (September 1998). "FokI dimerization is required for DNA cleavage". Proc. Natl. Acad....

com. Engineered TAL effectors can also be fused to the cleavage domain of FokI to create TAL effector nucleases (TALEN) or to meganucleases (nucleases with...

2011). "TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain". Nucleic Acids Research. 39 (1): 359–72. doi:10.1093/nar/gkq704...

PLACE IN THE FINALS". www.daviscup.com. Retrieved 27 March 2023. "Emotional Foki Consoles Injured Friend Humbert In Montpellier". www.atptour.com. 8 February...

2011). "TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain". Nucleic Acids Research. 39 (1): 359–72. doi:10.1093/nar/gkq704...