In molecular biology, G-quadruplex secondary structures (G4) are formed in nucleic acids by sequences that are rich in guanine. They are helical in shape...

intercalated-motif DNA, are cytosine-rich four-stranded quadruplex DNA structures, similar to the G-quadruplex structures that are formed in guanine-rich regions...

Look up quadruplex in Wiktionary, the free dictionary. Quadruplex may refer to: Quadruplex (New Orleans), a softball complex in New Orleans City Park Quadruplex...

pairs are observed in alternative structures such as the four-stranded G-quadruplex structures that form in DNA and RNA. Hoogsteen pairs have quite different...

normally located at the telomeres (the ends of the chromosomes). The G-quadruplex can either be parallel or antiparallel depending on the loop configuration...

classes of cruciform DNA have been described; folded and unfolded. G-quadruplex G-quadruplex secondary structures (G4) are formed in nucleic acids by sequences...

needed] There are also triple-stranded DNA forms and quadruplex forms such as the G-quadruplex and the i-motif. Twin helical strands form the DNA backbone...

Pontiac G4, a compact car sold in Mexico G4 EA H1N1, a strain of influenza G-quadruplex, a DNA secondary structure Group 4 element, a class of elements on the...

improved drugs with enhanced specificity. He has led in the study of G-quadruplex nucleic acids as therapeutic targets, especially focussing on their structure...

tetrad (also known as a G-tetrad or G-quartet) and when two or more guanine tetrads stack on top of each other, they form a G-quadruplex. These complex structures...

flat four-base units then stack on top of each other to form a stable G-quadruplex structure. These structures are stabilized by hydrogen bonding between...

microsatellites lead to the formation of secondary DNA structures (e.g. G-quadruplex) and rely on WRN to repair these bulky lesions. Because of this therapeutic...

four guanine residues form a near planar base quartet, referred to as G-quadruplex, where each guanine participates in base pairing with its neighboring...

enantioselectivity were related to the DNA sequence. The hemin/G-Quadruplex DNAzyme consists of G-Quadruplex forming DNA that can bind the co-factor hemin (a.k.a...

Anti-thrombin aptamers are G-quadruplex-bearing oligonucleotides, which recognizes the exosites of human thrombin. The first anti-thrombin aptamer, TBA...

the structure. Usually, there are at least two guanine tetrads in a G-quadruplex, and they often feature Hoogsteen-style hydrogen bonding. Guanine tetrads...

Lin & Chun-Ting Zhang (2008). "Greglist: a database listing potential G-quadruplex regulated genes". Nucleic Acids Res. 36 (suppl 1) (Database issue): D372–D376...

miRNA:miRNA* pairing also affects cleavage. Some of the G-rich pre-miRNAs can potentially adopt the G-quadruplex structure as an alternative to the canonical stem-loop...

with two helical strands and an internal bulge with a G-quadruplex motif. It is at this G-quadruplex that the fluorophore binds. Based on crystallographic...

form a quadruplex in RNA by Hoogsteen hydrogen bonds to form a “Hoogsteen ring” (See Figure). G-C and A-U pairs can also form base quadruplex with a combination...

mainly of tandem TTAGGG repeats. These repeats fold into highly organized G quadruplex structures which protect the ends of chromosomal DNA from degradation...

18.7049. PMC 297991. PMID 2780561. Lipps HJ, Rhodes D (August 2009). "G-quadruplex structures: in vivo evidence and function". Trends in Cell Biology. 19...

and reprogrammable human replication origin signatures associated with G-quadruplex consensus motifs". Nature Structural & Molecular Biology. 19 (8): 837–44...

indicates that several genes (including the proto-oncogene c-myc) have G-quadruplex motifs as potential regulatory signals. Promoters are important gene...

DNA Holliday junctions Triple-stranded DNA, quadruple-stranded DNA (G-quadruplex) Double-stranded hybrids of DNA and RNA (one strand is DNA, the other...

perfringens NagH) 16 kDa Optimers Flexible nucleic acid based scaffold; G-quadruplex 8-15 kDa Repebodies leucine-rich repeats Pronectin™ fourteenth fibronectin...

8-oxo-dG is formed in a guanine rich, potential G-quadruplex-forming sequence (PQS) in the coding strand of a promoter, active OGG1 excises the 8-oxo-dG and...

DHX36-specific motif, which recognizes the 5'-most G-quadruplex quartet. The OB-fold domain binds to the 3'-most G-tract sugar-phosphate backbone. Like all the...

functions as a 5' to 3' DNA helicase. The encoded protein can resolve G-quadruplex structures and RNA-DNA hybrids at the ends of chromosomes. It also prevents...

DNA oxidation at a guanine, occurs when an 8-oxo-dG is formed in a guanine rich, potential G-quadruplex-forming sequence (PQS) in the coding strand of a...