Glutaredoxin 5, also known as GLRX5, is a protein which in humans is encoded by the GLRX5 gene located on chromosome 14. This gene encodes a mitochondrial...
7 KB (870 words) - 08:25, 31 March 2024
Hereditary or congenital sideroblastic anemia may be X-linked or autosomal. GLRX5 has also been implicated. Acquired, or secondary, sideroblastic anemia develops...
16 KB (1,715 words) - 22:30, 6 September 2024
syndrome PHF8 X-Linked Recessive Sideroblastic anemia ABCB7, SLC25A38, GLRX5 recessive Sly syndrome GUSB recessive 1:250,000 Smith–Lemli–Opitz syndrome...
42 KB (983 words) - 18:14, 6 October 2024
HGNC:4330 P35754 6306 GLRX2 HGNC:16065 Q9NS18 6307 GLRX3 HGNC:15987 O76003 6308 GLRX5 HGNC:20134 Q86SX6 6309 GLS HGNC:4331 O94925 6310 GLS2 HGNC:29570 Q9UI32...
277 KB (17 words) - 18:41, 6 October 2024
signalling. Glutaredoxin subgroup InterPro: IPR014025 GLRX; GLRX2; GLRX3; GLRX5; PTGES2 Gleason FK, Holmgren A (December 1988). "Thioredoxin and related...
6 KB (651 words) - 03:04, 22 January 2023
[2Fe-2S] cluster transiently assembles on ISCU and is then transferred to GLRX5 in a cysteine desulfurase complex NFS1-LYRM4/ISD11 dependent process. ISCU...
15 KB (1,761 words) - 22:40, 22 April 2024
discover and characterize, including ISCU myopathy, sideroblastic anemia from GLRX5 deficiency, and lactic acidosis caused by mutations in NFU1 and BOLA3. The...
6 KB (620 words) - 05:12, 6 April 2024
hyperglycinemia is caused by mutations in LIAS, BOLA3 and the novel gene GLRX5". Brain. 137 (Pt 2): 366–79. doi:10.1093/brain/awt328. PMC 3914472. PMID 24334290...
3 KB (484 words) - 15:28, 12 August 2023
Anemia, sideroblastic, pyridoxine-refractory, autosomal recessive; 205950; GLRX5 Anemia, sideroblastic, pyridoxine-refractory, autosomal recessive; 205950;...
234 KB (18,877 words) - 15:43, 9 May 2024