GTPases are a large family of hydrolase enzymes that bind to the nucleotide guanosine triphosphate (GTP) and hydrolyze it to guanosine diphosphate (GDP)...

GTPase-activating proteins or GTPase-accelerating proteins (GAPs) are a family of regulatory proteins whose members can bind to activated G proteins and...

Small GTPases (EC 3.6.5.2), also known as small G-proteins, are a family of hydrolase enzymes that can bind and hydrolyze guanosine triphosphate (GTP)...

family of GTPases is a family of small (~21 kDa) signaling G proteins, and is a subfamily of the Ras superfamily. The members of the Rho GTPase family have...

All Ras protein family members belong to a class of protein called small GTPase, and are involved in transmitting signals within cells (cellular signal...

Synaptic Ras GTPase-activating protein 1, also known as synaptic Ras-GAP 1 or SYNGAP1, is a protein that in humans is encoded by the SYNGAP1 gene. SYNGAP1...

the free dictionary. Rho GTPase may refer to: Any member of the Rho family of GTPases The members of the Rho family of GTPases belonging to the Rho subclass...

nucleotide Exchange Factor). Ran's intrinsic GTPase-activity is activated through interaction with Ran GTPase activating protein (RanGAP), facilitated by...

In molecular biology, the interferon-inducible GTPase (IIGP) family of proteins is thought to play a role in intracellular defence. IIGP is predominantly...

GTPases and includes: Rnd1 Rnd2 Rnd3 (also called RhoE) Functions include downregulation of stress fibres and focal adhesions. Rho family of GTPases Ridley...

(~21 kDa) signaling G protein (more specifically a GTPase), and is a member of the Rho family of GTPases. TCL (TC10-like) shares 85% and 78% amino acid similarity...

activation by interacting with the TSC1/TSC2 protein complex. TSC2 is a GTPase activating protein (GAP). Its GAP activity interacts with a G protein called...

GTPase HRas, from "Harvey Rat sarcoma virus", also known as transforming protein p21 is an enzyme that in humans is encoded by the HRAS gene. The HRAS...

RAS p21 protein activator 1 or RasGAP (Ras GTPase activating protein), also known as RASA1, is a 120-kDa cytosolic human protein that provides two principal...

Rho-related GTPases from plants, otherwise known as ROPs, are involved in cell polarity through the regulation of cytoskeleton components like actin and...

Rac is a subfamily of the Rho family of GTPases, small (~21 kDa) signaling G proteins (more specifically a GTPase). Just as other G proteins, Rac acts as...

Tubulin GTPase (EC 3.6.5.6) is an enzyme with systematic name GTP phosphohydrolase (microtubule-releasing). This enzyme catalyses the following chemical...

(~21 kDa) signaling G protein (more specifically a GTPase), and is a member of the Rho family of GTPases. It is primarily active in the brain and plays a...

Interferon-inducible GTPase 5 also known as immunity-related GTPase cinema 1 (IRGC1) is an enzyme that in humans is coded by the IRGC gene. It is predicted...

protein (more specifically a GTPase), and is a member of the Rho family of GTPases. Chp was identified in 1998 as a GTPase interacting with the p21 activated...

Dynamin is a GTPase responsible for endocytosis in the eukaryotic cell. Dynamin is part of the "dynamin superfamily", which includes classical dynamins...

GTPase-activator protein for Ras-like GTPase is a family of evolutionarily related proteins. Ras proteins are membrane-associated molecular switches that...

factors (GEFs) are proteins or protein domains that activate monomeric GTPases by stimulating the release of guanosine diphosphate (GDP) to allow binding...

Small GTPAses is a peer-reviewed scientific journal covering research on small GTPases, including their structural biology, biochemical regulation, and...

ABR, RhoGEF and GTPase activating protein is a protein that in humans is encoded by the ABR gene. The ABR activator of RhoGEF and GTPase, also symbolized...

guanine nucleotide exchange factors that act on the Ras subfamily of small GTPases. The gene was so named because the Sos protein that it encoded was found...

"large" G proteins (as opposed to the subclass of smaller, monomeric small GTPases) are membrane-associated G proteins that form a heterotrimeric complex...

binding protein domain. They often interact with GTPases and could play a role in multiple Ras-like GTPase signalling pathways. This domain is present in...

this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic...

the nucleobase guanine. GDP is the product of GTP dephosphorylation by GTPases, e.g., the G-proteins that are involved in signal transduction. GDP is...