• Thumbnail for Galactosylceramide
    A galactosylceramide, or galactocerebroside is a type of cerebroside consisting of a ceramide with a galactose residue at the 1-hydroxyl moiety. The galactose...
    2 KB (163 words) - 11:14, 17 April 2023
  • Thumbnail for Krabbe disease
    Krabbe disease (KD) (also known as globoid cell leukodystrophy or galactosylceramide lipidosis) is a rare and often fatal lysosomal storage disease that...
    24 KB (2,486 words) - 16:18, 17 November 2024
  • α-Galactosylceramide (α-GalCer, KRN7000) is a synthetic glycolipid derived from structure-activity relationship studies of galactosylceramides isolated...
    4 KB (276 words) - 21:06, 7 June 2023
  • galactosylceramide sulfotransferase (EC 2.8.2.11) is an enzyme that catalyzes the chemical reaction 3'-phosphoadenylyl sulfate + a galactosylceramide...
    2 KB (183 words) - 18:36, 23 January 2024
  • Thumbnail for Cerebroside
    long-chain base present in ceramide. Galactosylceramide is the principal glycosphingolipid in brain tissue. Galactosylceramides are present in all nervous tissues...
    6 KB (723 words) - 14:38, 6 December 2023
  • from ceramide derivatives (galactosylceramides) by catalysing the hydrolysis of galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide...
    8 KB (989 words) - 19:48, 3 November 2024
  • Thumbnail for Sphingolipid
    Alternatively, it may be glycosylated by glucosylceramide synthase or galactosylceramide synthase. Additionally, it can be converted to sphingomyelin by the...
    25 KB (2,774 words) - 16:47, 24 September 2024
  • Thumbnail for Plasmid
    synthases responsible for the synthesis of glucuronosylceramide and α-galactosylceramide". The Journal of Biological Chemistry. 295 (31): 10709–10725. doi:10...
    55 KB (6,299 words) - 05:47, 14 November 2024
  • glycolipid antigens. The best known antigen of iNKT cells is alpha-galactosylceramide (αGalCer), which is a synthetic form of a chemical purified from the...
    14 KB (1,648 words) - 09:58, 18 July 2023
  • Structure of ceramide, galactosylceramide and glucosylceramide....
    28 KB (3,180 words) - 05:01, 11 November 2024
  • Thumbnail for Beta-2 microglobulin
    1zt4: The crystal structure of human CD1d with and without alpha-Galactosylceramide 1zvs: Crystal structure of the first class MHC mamu and Tat-Tl8 complex...
    17 KB (2,118 words) - 05:47, 29 September 2024
  • Thumbnail for Sigma-1 receptor
    S2CID 4378593. Hayashi T, Su TP (October 2004). "Sigma-1 receptors at galactosylceramide-enriched lipid microdomains regulate oligodendrocyte differentiation"...
    28 KB (3,052 words) - 13:43, 16 November 2024
  • Thumbnail for GAL3ST1
    Galactosylceramide sulfotransferase is an enzyme that in humans is encoded by the GAL3ST1 gene. Sulfonation, an important step in the metabolism of many...
    7 KB (657 words) - 02:26, 1 December 2023
  • for the lysosomal catabolism of certain galactolipids, including galactosylceramide and psychosine. Henrissat B, Callebaut I, Fabrega S, Lehn P, Mornon...
    5 KB (490 words) - 21:20, 6 August 2023
  • caused by biofilm from influenza infection. New components like α-galactosylceramide (α-GalCer) are also being researched to be used as nasal vaccines...
    29 KB (3,397 words) - 23:36, 24 August 2024
  • Thumbnail for Moriya Tsuji
    Moriya Tsuji, Moriya (4 March 2002). "Natural Killer T Cell Ligand α-Galactosylceramide Enhances Protective Immunity Induced by Malaria Vaccines". Journal...
    18 KB (2,096 words) - 22:09, 15 September 2024
  • Thumbnail for Anoctamin 6
    exposure on blood platelet dendritic cell chemotaxis calcium activated galactosylceramide scrambling activation of blood coagulation via clotting cascade positive...
    5 KB (616 words) - 09:06, 6 October 2024
  • Bacteroides fragilis produces the immune modulatory sphingolipid alpha-galactosylceramide, showed that the production of neurotransmitters is common among commensal...
    9 KB (965 words) - 08:36, 17 November 2024
  • Thumbnail for CD1D
    CD1d is also known as R3G1 Some of the known ligands for CD1d are: α-galactosylceramide (α-GalCer), a compound originally derived from the marine sponge Agelas...
    15 KB (1,840 words) - 04:22, 15 October 2024
  • CD1 are not well characterized, but a synthetic glycolipid, alpha-galactosylceramide (α-GalCer), originally isolated from a compound found in a marine...
    15 KB (1,695 words) - 16:50, 21 April 2024
  • sulfotransferase EC 2.8.2.10: Renilla-luciferin sulfotransferase EC 2.8.2.11: galactosylceramide sulfotransferase EC 2.8.2.12: deleted, identical to EC 2.8.2.8, [heparan...
    215 KB (21,664 words) - 23:41, 8 May 2024
  • type I NKT cells recognize the marine sponge-derived glycolipid, α-galactosylceramide (α-GalCer). After the encounter with the antigen Type I NKT cells...
    13 KB (1,585 words) - 05:15, 24 September 2023
  • + N-acylsphingosine ⇌ {\displaystyle \rightleftharpoons } UDP + D-galactosylceramide Thus, the two substrates of this enzyme are UDP-galactose and N-acylsphingosine...
    2 KB (127 words) - 18:17, 23 January 2024
  • Thumbnail for UGT8
    Biological process lipid metabolism neuron projection morphogenesis galactosylceramide biosynthetic process glycosphingolipid metabolic process peripheral...
    5 KB (603 words) - 04:17, 8 November 2023
  • Thumbnail for B4GALT3
    process protein glycosylation keratan sulfate biosynthetic process galactosylceramide biosynthetic process carbohydrate metabolic process Sources:Amigo...
    7 KB (830 words) - 09:38, 6 January 2024
  • Thumbnail for Battenin
    Persaud-Sawin DA, Miller S, Boustany RM (June 2008). "CLN3p impacts galactosylceramide transport, raft morphology, and lipid content". Pediatric Research...
    11 KB (1,268 words) - 17:34, 3 June 2024
  • galactosyltransferase. Shayman, James (2006). "Glucosylceramide and Galactosylceramide Synthase". Sphingolipid Biology. Tokyon: Springer. pp. 83–94. doi:10...
    2 KB (219 words) - 12:28, 26 August 2023
  • converted into complex lipids as sphingomyelins and glycosphingolipids (galactosylceramides, gangliosides, cerebrosides ...). Instead, they have toxic effects...
    19 KB (2,298 words) - 09:21, 17 March 2024
  • Thumbnail for GAL3ST3
    function galactose 3-O-sulfotransferase activity transferase activity galactosylceramide sulfotransferase activity proteoglycan sulfotransferase activity 3'-phosphoadenosine...
    4 KB (560 words) - 00:28, 4 March 2023
  • Thumbnail for Prosaposin
    degranulation ganglioside GM1 transport to membrane corneocyte development galactosylceramide catabolic process G protein-coupled receptor signaling pathway hearing...
    14 KB (1,791 words) - 14:17, 9 October 2024