A galactosylceramide, or galactocerebroside is a type of cerebroside consisting of a ceramide with a galactose residue at the 1-hydroxyl moiety. The galactose...
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Krabbe disease (redirect from Galactosylceramide lipidosis)
Krabbe disease (KD) (also known as globoid cell leukodystrophy or galactosylceramide lipidosis) is a rare and often fatal lysosomal storage disease that...
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α-Galactosylceramide (α-GalCer, KRN7000) is a synthetic glycolipid derived from structure-activity relationship studies of galactosylceramides isolated...
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galactosylceramide sulfotransferase (EC 2.8.2.11) is an enzyme that catalyzes the chemical reaction 3'-phosphoadenylyl sulfate + a galactosylceramide...
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long-chain base present in ceramide. Galactosylceramide is the principal glycosphingolipid in brain tissue. Galactosylceramides are present in all nervous tissues...
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from ceramide derivatives (galactosylceramides) by catalysing the hydrolysis of galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide...
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Alternatively, it may be glycosylated by glucosylceramide synthase or galactosylceramide synthase. Additionally, it can be converted to sphingomyelin by the...
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synthases responsible for the synthesis of glucuronosylceramide and α-galactosylceramide". The Journal of Biological Chemistry. 295 (31): 10709–10725. doi:10...
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glycolipid antigens. The best known antigen of iNKT cells is alpha-galactosylceramide (αGalCer), which is a synthetic form of a chemical purified from the...
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Structure of ceramide, galactosylceramide and glucosylceramide....
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1zt4: The crystal structure of human CD1d with and without alpha-Galactosylceramide 1zvs: Crystal structure of the first class MHC mamu and Tat-Tl8 complex...
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S2CID 4378593. Hayashi T, Su TP (October 2004). "Sigma-1 receptors at galactosylceramide-enriched lipid microdomains regulate oligodendrocyte differentiation"...
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Galactosylceramide sulfotransferase is an enzyme that in humans is encoded by the GAL3ST1 gene. Sulfonation, an important step in the metabolism of many...
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for the lysosomal catabolism of certain galactolipids, including galactosylceramide and psychosine. Henrissat B, Callebaut I, Fabrega S, Lehn P, Mornon...
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caused by biofilm from influenza infection. New components like α-galactosylceramide (α-GalCer) are also being researched to be used as nasal vaccines...
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Moriya Tsuji, Moriya (4 March 2002). "Natural Killer T Cell Ligand α-Galactosylceramide Enhances Protective Immunity Induced by Malaria Vaccines". Journal...
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exposure on blood platelet dendritic cell chemotaxis calcium activated galactosylceramide scrambling activation of blood coagulation via clotting cascade positive...
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Bacteroides fragilis produces the immune modulatory sphingolipid alpha-galactosylceramide, showed that the production of neurotransmitters is common among commensal...
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CD1d is also known as R3G1 Some of the known ligands for CD1d are: α-galactosylceramide (α-GalCer), a compound originally derived from the marine sponge Agelas...
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CD1 are not well characterized, but a synthetic glycolipid, alpha-galactosylceramide (α-GalCer), originally isolated from a compound found in a marine...
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sulfotransferase EC 2.8.2.10: Renilla-luciferin sulfotransferase EC 2.8.2.11: galactosylceramide sulfotransferase EC 2.8.2.12: deleted, identical to EC 2.8.2.8, [heparan...
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type I NKT cells recognize the marine sponge-derived glycolipid, α-galactosylceramide (α-GalCer). After the encounter with the antigen Type I NKT cells...
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+ N-acylsphingosine ⇌ {\displaystyle \rightleftharpoons } UDP + D-galactosylceramide Thus, the two substrates of this enzyme are UDP-galactose and N-acylsphingosine...
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Biological process lipid metabolism neuron projection morphogenesis galactosylceramide biosynthetic process glycosphingolipid metabolic process peripheral...
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process protein glycosylation keratan sulfate biosynthetic process galactosylceramide biosynthetic process carbohydrate metabolic process Sources:Amigo...
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Persaud-Sawin DA, Miller S, Boustany RM (June 2008). "CLN3p impacts galactosylceramide transport, raft morphology, and lipid content". Pediatric Research...
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galactosyltransferase. Shayman, James (2006). "Glucosylceramide and Galactosylceramide Synthase". Sphingolipid Biology. Tokyon: Springer. pp. 83–94. doi:10...
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converted into complex lipids as sphingomyelins and glycosphingolipids (galactosylceramides, gangliosides, cerebrosides ...). Instead, they have toxic effects...
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function galactose 3-O-sulfotransferase activity transferase activity galactosylceramide sulfotransferase activity proteoglycan sulfotransferase activity 3'-phosphoadenosine...
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degranulation ganglioside GM1 transport to membrane corneocyte development galactosylceramide catabolic process G protein-coupled receptor signaling pathway hearing...
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