A genetically modified mouse, genetically engineered mouse model (GEMM) or transgenic mouse is a mouse (Mus musculus) that has had its genome altered through...
14 KB (1,709 words) - 04:14, 7 November 2024
A knockout mouse, or knock-out mouse, is a genetically modified mouse (Mus musculus) in which researchers have inactivated, or "knocked out", an existing...
15 KB (1,889 words) - 15:09, 11 September 2024
A humanized mouse is a genetically modified mouse that has functioning human genes, cells, tissues and/or organs. Humanized mice are commonly used as...
30 KB (3,633 words) - 21:41, 14 June 2024
A genetically modified organism (GMO) is any organism whose genetic material has been altered using genetic engineering techniques. The exact definition...
223 KB (24,627 words) - 12:34, 17 November 2024
genetically modified if its genetic material has been altered through any method, including conventional breeding. A 'GMO' is a genetically modified organism...
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Genetically modified animals are animals that have been genetically modified for a variety of purposes including producing drugs, enhancing yields, increasing...
102 KB (11,029 words) - 03:36, 21 November 2024
Agrobacterium-mediated recombination and microinjection. The first genetically modified animal was a mouse created in 1974 by Rudolf Jaenisch. In 1976, the technology...
59 KB (6,419 words) - 05:18, 5 September 2024
knockout mouse is a genetically modified mouse that has had one or more of its genes made inoperable through a gene knockout. Experimental mouse model systems...
16 KB (1,769 words) - 01:18, 15 October 2024
Oncomouse (redirect from Harvard mouse)
The OncoMouse or Harvard mouse is a type of laboratory mouse (Mus musculus) that has been genetically modified using modifications designed by Philip Leder...
8 KB (1,034 words) - 16:03, 4 December 2023
Genetically modified mammals are mammals that have been genetically engineered. They are an important category of genetically modified organisms. The majority...
18 KB (1,844 words) - 20:53, 27 July 2024
Transgene (category Genetic engineering)
The two most common types of genetically modified mice are knockout mice and oncomice. Knockout mice are a type of mouse model that uses transgenic insertion...
29 KB (3,583 words) - 18:09, 29 April 2024
Dry shipper (category Genetically modified organisms)
carry materials such as spermatozoa or preimplantation embryos of genetically modified mouse strains, safeguarding the integrity and viability of these research...
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from genetically modified mouse that express fluorescent proteins such as green fluorescent proteins, the emission mode of OPT can yield 3D genetic expression...
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mice can then be bred to create transgenic lines. Transgenesis Genetically modified mouse Biology: The Unity and Diversity of Life Nanoinjection David B...
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is known as CRISPR/Cas-based gene therapy. Mammalian cells can be genetically modified using the straightforward, affordable, and extremely specific CRISPR/Cas...
93 KB (10,239 words) - 14:06, 19 November 2024
technologies, the company created the world’s largest repository of genetically modified mouse embryonic stem cells, known as OmniBank, and established a large-scale...
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Ralph L. Brinster (section Stem cells injection into mouse embryos produce the first prototype transgenic animal)
acclaimed Zadie Smith novel "White Teeth" features prominently a genetically modified mouse "Futuremouse", based loosely on the transgenic experiments of...
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genetically altered mice an invention, court declares," CMAJ, Oct. 3, 2000, 163(7). CBC News, "Supreme Court rejects patent on genetically-modified mouse...
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PEPCK-Cmus mice are genetically modified mice (Mus musculus) which as a result of their modification have up to 100 times the concentration of the PEPCK-C...
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and rats, are used in experiments each year. A knockout mouse is a genetically modified mouse with an inactivated gene, replaced or disrupted with an...
222 KB (23,157 words) - 21:11, 12 November 2024
C57BL/6 (redirect from Inbred c57bl mouse)
common inbred strain of laboratory mouse. It is the most widely used "genetic background" for genetically modified mice for use as models of human disease...
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Biological patents in the United States (category Genetic engineering in the United States)
focused on human embryonic stem cells. In another example, a genetically modified mouse, dubbed the Oncomouse, that is useful for studying cancer, was...
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reverse the premature aging and several tissue dysfunctions in a genetically modified mouse model of the disease. Vitamin C supplementation also appeared...
35 KB (4,518 words) - 16:31, 2 November 2024
inserting new genetic material into a rice plant, all the descendants of the genetically modified rice plant are a strain with unique genetic information...
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was a challenge. However, in combination with RNA-seq data and genetically modified mouse models, several labeling markers, i.e. VGLUT3, TAFA4, CaV3.2,...
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electric boat Rudolf Jaenisch (born 1942), Germany/U.S. – first Genetically modified mouse Alcinous Burton Jamison (1851–1938), American physician, inventor...
107 KB (12,077 words) - 15:11, 20 November 2024
fine genetic mapping, and capture a large portion of the genetic diversity of the mouse genome. This project has resulted in over 1,000 genetically diverse...
62 KB (6,038 words) - 03:06, 21 November 2024
Monsanto Canada Inc v Schmeiser (category Genetically modified organisms in agriculture)
Schmeiser's intentionally growing genetically modified plants constituted "use" of Monsanto's patented genetically modified plant cells. By a 5-4 majority...
28 KB (3,793 words) - 21:46, 29 July 2024
SHIRPA (redirect from Modified SHIRPA)
experimental procedures used by scientists to characterize the phenotype of genetically modified laboratory mice. The protocols are designed to test muscle function...
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Pinky and the Brain (category Fictional genetically engineered characters)
Paulsen) is a genetically modified mouse who shares the same cage as Brain at Acme Labs. Pinky is an extremely unstable and hyperactive mouse. He has several...
62 KB (7,453 words) - 11:00, 2 November 2024