GnRH neurons, or gonadotropin-releasing hormone expressing neurons, are the cells in the hypothalamic infundibular nucleus in the brain that control the...

hormone (LH) from the anterior pituitary. GnRH is a tropic peptide hormone synthesized and released from GnRH neurons within the hypothalamus. The peptide...

Although GnRH is located in many areas such as the pituitary gland and the GnRH neurons, research proves that GnRH is highly dependent upon GnRH neuron activation...

other indications. Some GnRH antagonists, such as cetrorelix, are similar in structure to natural GnRH (a hormone made by neurons in the hypothalamus) but...

secretion of GnRH. GnRH neurons lack sex steroid receptors and mediators such as kisspeptin stimulate GnRH neurons for pulsatile secretion of GnRH. Despite...

gonadotropin-releasing hormone (GnRH) release in the hypothalamic–pituitary–gonadal (HPG) axis. Sex steroids released from the gonads act on KNDy neurons as inhibitors...

gonadotropin-releasing hormone (GnRH). Agonist binding to the GnRH receptor activates the Gq/11 family of heterotrimeric G proteins. The GnRHR is expressed on the...

neurons also secrete melanocyte-stimulating hormone, which suppresses appetite.: 419  GnRH neurons have also been found. These neurons secrete GnRH and...

migration, and differentiation of neurons. To assist with migration, NDNF shows neuro-repulsive effects on GnRH neurons. Loss of function (LoF) in the NDNF...

GABA-secreting neurons that innervate GnRH-1 neurons also can stimulate GnRH-1 release. These GABA neurons also possess ERs and may be responsible for the GnRH-1 surge...

in the gonadotropin-releasing hormone (GnRH) system of the ewe: changes in synaptic inputs onto GnRH neurons". Endocrinology. 138 (3): 1240–1250. doi:10...

in KNDy neurons of the hypothalamus, are critical parts of the control system that switches on the release of GnRH at the start of puberty. GnRH (gonadotropin-releasing...

animals. Gonadotropin-releasing hormone (GnRH) is secreted from the hypothalamus by GnRH-expressing neurons. The anterior portion of the pituitary gland...

(RP3V). This area is full of kisspeptin-expressing neurons and is involved in regulating GnRH neurons, and is responsible for the LH surge in female mice...

– a hormone that is made by neurons in the hypothalamus. GnRH antagonists compete with natural GnRH for binding to GnRH receptors in the pituitary gland...

fertility in female animals. Killing specific cells in either the brain (GnRH neurons) or the pituitary gland (gonadotrophs) that are vital for reproduction...

gonadotropin-releasing hormone ( GnRH ) neurons, and in 2023 was awarded a Marsden grant to study the role of distinct populations of GnRH neurons in the brain. Campbell...

participate in the release of gonadotropin-releasing hormone (GnRH). GnRH is released by GnRH neurons located in the arcuate nucleus in the hypothalamus. These...

due to the defective migration of GNRH neurons from olfactory placode to hypothalamus, leading to congenital GNRH deficiency. This leads to olfactory...

gonadotropin-releasing hormone agonists (GnRH agonists) and steroidal anti-androgens. GnRH agonists are a group of drugs intended to activate GnRH receptors in the anterior...

through GnRH secretion. GABA neurons, KNDy neurons, and leptin are specifically responsible for alterations in GnRH secretion. GABA and KNDy neurons synapse...

Some GnIH neuron terminals in both mammalian and avian species project to the median eminence. GnIH and GnRH (gonadotropin releasing hormone) neurons exist...

occur in several types of excitable cells, which include animal cells like neurons and muscle cells, as well as some plant cells. Certain endocrine cells...

hypothalamic pathway responsible for GnRH secretion. The periventricular nucleus has also been shown to have many neurons that express kisspeptin, which generates...

linked to the transport of GnRH between the median eminence and the anterior pituitary. Neuronal projections of GnRH neurons actually end at the median...

axophilic migration. An example of this mode of migration is in GnRH-expressing neurons, which make a long journey from their birthplace in the nose, through...

to GnRH and gonadotropin secretion. Preferred treatment for CPP is a GnRH receptor agonist. These medications are modified variations of natural GnRH. They...

the axons of olfactory neurons to attach to the central nervous system in the mice model. During neural development, GnRH neurons migrate through one of...

metabolic function. KISS1 neurons located in the arcuate nucleus (ARC) of the mediobasal hypothalamus (MBH) project to GnRH neurons in the median eminence...

function, as evidenced by the case of GnRH agonists, which cause functional inhibition of the receptor for GnRH due to profound downregulation in response...