critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen (HLA) complex. The HLA complex helps the immune system...
17 KB (1,889 words) - 01:57, 10 March 2024
Human leukocyte antigen (HLA) B27 (subtypes B*2701-2759) is a class I surface molecule encoded by the B locus in the major histocompatibility complex (MHC)...
16 KB (1,514 words) - 07:57, 4 September 2024
Human leukocyte antigen (redirect from HLA antigen)
discovery as factors in organ transplants. HLAs corresponding to MHC class I (A, B, and C), all of which are the HLA Class1 group, present peptides from inside...
51 KB (5,942 words) - 07:28, 11 November 2024
Antigens most responsible for graft loss are HLA-DR (first six months), HLA-B (first two years), and HLA-A (long-term survival). Good matching of these...
31 KB (2,293 words) - 12:25, 28 December 2023
HLA-A is a group of human leukocyte antigens (HLA) that are encoded by the HLA-A locus, which is located at human chromosome 6p21.3. HLA is a major histocompatibility...
27 KB (3,411 words) - 01:57, 10 March 2024
non-self epitope on one of their various HLA protein forms (HLA-A, HLA-B, HLA-C, HLA-DM, HLA-DO, HLA-DP, HLA-DQ, or HLA-DR) can bind to a T-cell receptor and...
56 KB (5,871 words) - 00:47, 10 November 2024
alloantigen). Nevertheless, the β2 microglobulin gene is outside of the MHC (HLA) locus, on a different chromosome. An additional function is association...
17 KB (2,118 words) - 05:47, 29 September 2024
necrolysis (TEN). The frequency of the HLA-B*5801 allele varies between ethnicities: Han Chinese and Thai populations have HLA-B*5801 allele frequencies of around...
31 KB (2,798 words) - 23:42, 18 October 2024
HLA-B51 (B51) is an HLA-B serotype. The serotype identifies the more common HLA-B*51 gene products. B51 is a split antigen of the broad antigen B5, and...
16 KB (960 words) - 01:10, 1 June 2024
patients, notably genes related to class I MHC including HLA-B*08, HLA-B*27, HLA-B*38, and HLA-B*39. Other genes relating to the immune system and central...
32 KB (3,440 words) - 01:34, 28 October 2024
HLA-C alleles that are Class-I MHC receptors. HLA-C, localized proximal to the HLA-B locus, is located on the distal end of the HLA region. Most HLA-C:B...
8 KB (1,014 words) - 03:35, 28 December 2023
HLA-DR1 (DR1) is a HLA-DR serotype that recognizes the DRB1*01 gene products. It has been observed to be common among centenarians. The serology for the...
20 KB (1,596 words) - 01:46, 28 November 2023
MHC class I (section PirB and visual plasticity)
polymorphic HLA-A (HLA-A) HLA-B (HLA-B) HLA-C (HLA-C) Less polymorphic HLA-E (HLA-E) HLA-F (HLA-F) HLA-G (HLA-G) HLA-K (pseudogene) HLA-L (pseudogene)...
21 KB (2,610 words) - 08:24, 9 August 2024
Major histocompatibility complex (section HLA biology)
most studied HLA genes are the nine classical MHC genes: HLA-A, HLA-B, HLA-C, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQB1, HLA-DRA, and HLA-DRB1. In humans...
58 KB (6,785 words) - 20:25, 21 September 2024
HLA-B35 (B35) is an HLA-B serotype. The serotype identifies the more common HLA-B*35 gene products. B35 is one of the largest B serotype groups, it currently...
6 KB (149 words) - 14:44, 26 June 2024
antigen B locus namely HLA-B*5701. The mechanism for this hypersensitivity reaction is due to abacavir binding in the antigen-binding cleft of HLA-B*57:01...
33 KB (2,771 words) - 17:59, 28 July 2024
HLA-B57 (B57) is an HLA-B serotype. B57 is a split antigen from the B17 broad antigen, the sister serotype being B58. The serotype identifies the more...
11 KB (438 words) - 14:42, 26 June 2024
people with a particular human leukocyte antigen gene-variant (allele), HLA-B*1502. Odds ratios for the development of SJS or TEN in people who carry...
34 KB (3,201 words) - 07:48, 11 November 2024
cells, macrophages, and B cells. They load processed peptides onto MHC class II (i.e. HLA-DM, HLA-DO, HLA-DP, HLA-DQ, or HLA-DR) proteins and thereon...
35 KB (4,080 words) - 05:51, 8 September 2024
B12 (disambiguation) (redirect from B 12)
manufactured by Buffet Crampon Boron-12 (B-12 or 12B), an isotope of boron Big 12 Conference HLA-B12, an HLA-B serotype IgG1-b12, an antibody against the...
1 KB (241 words) - 21:37, 10 November 2023