• Thumbnail for HLA-DR2
    HLA-DR2 (DR2) of the HLA-DR serotype system, is a broad antigen serotype that is now preferentially covered by HLA-DR15 and HLA-DR16 serotype group. This...
    4 KB (333 words) - 09:16, 3 April 2024
  • Thumbnail for HLA-DR
    with certain HLA-DRB1 types. The HLA-DRB5 locus encodes the HLA-DR51 specificity, which is typically invariable, and is linked to the HLA-DR2 types. linkage...
    31 KB (2,293 words) - 12:25, 28 December 2023
  • Thumbnail for Human leukocyte antigen
    The human leukocyte antigen (HLA) system is a complex of genes on chromosome 6 in humans that encode cell-surface proteins responsible for regulation...
    51 KB (5,942 words) - 15:58, 25 September 2024
  • Thumbnail for HLA-DRB1
    HLA class II histocompatibility antigen, DRB1 beta chain is a protein that in humans is encoded by the HLA-DRB1 gene. DRB1 encodes the most prevalent beta...
    6 KB (677 words) - 21:44, 22 October 2024
  • found dominant subpopulations characterized by higher expression of HLA-DR2 and HLA-DR15 (mean age of two groups: 34 and 21 years), FOXP3, CD95, and CCR4;...
    40 KB (4,353 words) - 10:50, 24 October 2024
  • Thumbnail for HLA-DR15
    Ireland to Central Asia. DR15 is part of the older HLA-DR2 serotype group which also contains the similar HLA-DR16 antigens. Serotypes are unknown for the following...
    16 KB (1,100 words) - 13:55, 26 March 2024
  • Thumbnail for HLA-DR1
    HLA-DR1 (DR1) is a HLA-DR serotype that recognizes the DRB1*01 gene products. It has been observed to be common among centenarians. The serology for the...
    20 KB (1,596 words) - 01:46, 28 November 2023
  • frequently HLA-DR2, and in another population study it was found that DR-15 is associated with ATA in systemic sclerosis. In addition to HLA-DR, the protein...
    9 KB (870 words) - 07:54, 22 August 2024
  • Thumbnail for HLA-DRA
    HLA class II histocompatibility antigen, DR alpha chain is a protein that in humans is encoded by the HLA-DRA gene. HLA-DRA encodes the alpha subunit...
    9 KB (1,145 words) - 03:20, 25 December 2023
  • follows: HLA Cw*0702 : B*0702 : DRB1*1501 : DQA1*0102 : DQB1*0602 The older literature may describe this haplotype in two different ways. One B7-DR2-DQ6 derives...
    13 KB (1,237 words) - 01:13, 1 June 2024
  • Thumbnail for Anti-SSA/Ro autoantibodies
    immune response. Anti-Ro/SSA associates with the HLA II alleles HLA-DR3 and HLA-DR2, as well as some HLA-DQ alleles. The T-cell response plays a role in...
    14 KB (1,783 words) - 03:28, 12 August 2023
  • Thumbnail for Major histocompatibility complex, class II, DQ alpha 1
    "Molecular studies of a rare DR2/LD-5a/DQw3 HLA class II haplotype. Multiple genetic mechanisms in the generation of polymorphic HLA class II genes". J. Immunol...
    11 KB (1,225 words) - 15:04, 12 August 2023
  • Thumbnail for HLA-DR16
    modest frequencies. DR16 is part of the older HLA-DR2 serotype group which also contains the similar HLA-DR15 antigens. DR16 is associated with Chaga's...
    11 KB (849 words) - 13:54, 8 March 2024
  • Thumbnail for Aphthous stomatitis
    genetically predisposed to developing oral ulceration. HLA-B12, HLA-B51, HLA-Cw7, HLA-A2, HLA-A11, and HLA-DR2 are examples of human leukocyte antigen types associated...
    50 KB (5,155 words) - 12:38, 19 October 2024
  • Thumbnail for Myelin basic protein
    MYELIN BASIC PROTEIN IN DIFFERENT REGISTERS BY TWO HLA-DR2 ALLELES 1bx2: CRYSTAL STRUCTURE OF HLA-DR2 (DRA*0101,DRB1*1501) COMPLEXED WITH A PEPTIDE FROM...
    25 KB (2,983 words) - 23:11, 17 August 2024
  • Thumbnail for HLA-DRB5
    "Molecular studies of a rare DR2/LD-5a/DQw3 HLA class II haplotype. Multiple genetic mechanisms in the generation of polymorphic HLA class II genes". J. Immunol...
    8 KB (1,064 words) - 05:42, 25 December 2023
  • Thumbnail for HLA-DR3
    mellitus type 1. DR3-DR2 is the serological marker for HLA-DQ2.5cis isoform. Although it cannot identify the alpha ".5" chain of HLA DQ, DQA1*05:01 gene...
    9 KB (697 words) - 02:42, 27 January 2024
  • Thumbnail for Autoimmunity
    invaders, but may also give rise to lymphocytes capable of self-reactivity. HLA DR2 is strongly positively correlated with systemic lupus erythematosus, narcolepsy...
    51 KB (5,880 words) - 17:38, 2 November 2024
  • Thumbnail for HLA-DR51
    allele groups. HLA-DR2 HLA-DR15 - DRB1*15 HLA-DR16 - DRB1*16 Gorski J, Rollini P, Mach B (1987). "Structural comparison of the genes of two HLA-DR supertypic...
    6 KB (371 words) - 04:27, 13 August 2023
  • Thumbnail for HLA-DR11
    PMID 16121403. Hu C, Wu C, Lee C, Wu C, Tsai H, Chen P, Hsu P (2006). "HLA-DR11 and HLA-DR2 are negatively associated with autoantibody production in chronic...
    12 KB (829 words) - 19:54, 12 August 2023
  • Thumbnail for Acute posterior multifocal placoid pigment epitheliopathy
    accompanies it. It is associated with an increased incidence of both HLA-B7 and HLA-DR2. The underlying etiology of APMPPE continues to cause debate. The...
    11 KB (1,195 words) - 01:59, 16 June 2024
  • of HLA-A2, HLA-A68, and HLA-B27. Ultimately, papain-solubilized fragments of the human class II MHC antigens HLA-DR1, HLA-DR2, HLA-DR3, HLA-DR4, HLA-DR7...
    16 KB (1,479 words) - 08:17, 30 August 2024
  • Wieczorek S, Dahmen N, Kasten M, et al. (2004). "A rare form of narcolepsy (HLA-DR2-) shows possible association with (functionally relevant) alpha-interferon...
    4 KB (529 words) - 12:34, 29 January 2023
  • Human leukocyte antigens (HLA) began as a list of antigens identified as a result of transplant rejection. The antigens were initially identified by categorizing...
    45 KB (5,515 words) - 12:41, 28 September 2024
  • Thumbnail for Goodpasture syndrome
    peak age ranges for the onset of the disease are 20–30 and 60–70 years. HLA-DR § DR2 Pulmonary-renal syndrome "Goodpasture Syndrome". www.hopkinsmedicine...
    14 KB (1,428 words) - 23:54, 3 March 2024
  • Thumbnail for Narinder Kumar Mehra
    in India, he studied HLA-linked genes and identified that a subtype of HLA-DR2 carried a unique class II haplotype which made humans susceptible to diseases...
    36 KB (3,143 words) - 10:49, 1 September 2024
  • Thumbnail for Dirucotide
    disease progression for five years in progressive MS patients with HLA-DR2 or HLA-DR4 immune response genes. It does not seem to be effective in patients...
    8 KB (577 words) - 19:31, 20 December 2023
  • HLA-DR2 MeSH D23.050.301.500.410.400.440.455 – HLA-DR3 MeSH D23.050.301.500.410.400.440.460 – HLA-DR4 MeSH D23.050.301.500.410.400.440.465 – HLA-DR5...
    86 KB (8,039 words) - 16:46, 9 February 2024
  • There are many human leukocyte antigen (HLA) alleles associated with conditions of or affecting the human integumentary system List of allergens List...
    3 KB (183 words) - 00:11, 23 February 2024
  • Isoform Nucleoporin 210kDa Autoantigen gene NUP210 Affected organ(s) Bile Duct Associated Disease(s) Primary biliary cirrhosis HLA associations DR2 (weak)...
    4 KB (447 words) - 21:55, 9 October 2023