Hyaluronan synthases (HAS) are membrane-bound enzymes that use UDP-α-N-acetyl-D-glucosamine and UDP-α-D-glucuronate as substrates to produce the glycosaminoglycan...

əljʊəˈrɒnɪk/; abbreviated HA; conjugate base hyaluronate), also called hyaluronan, is an anionic, nonsulfated glycosaminoglycan distributed widely throughout...

Hyaluronan synthase 2 is an enzyme that in humans is encoded by the HAS2 gene. Hyaluronan or hyaluronic acid is a high molecular weight unbranched polysaccharide...

Hyaluronan synthase 1 is an enzyme that in humans is encoded by the HAS1 gene. Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched...

Hyaluronan synthase 3 is an enzyme that in humans is encoded by the HAS3 gene. The protein encoded by this gene is involved in the synthesis of the unbranched...

proteoglycan Hyaluronic acid (also known as hyaluronan), which is synthesized by integral membrane synthases, which immediately secrete the dynamically...

American School, an international school in Hsinchu City, Taiwan Hyaluronan synthase, an enzyme Have (disambiguation) Hass (disambiguation) Haas (disambiguation)...

myocardial infarction, exists in 3 isoforms. Hyaluronan synthase, the enzyme responsible for the production of hyaluronan, has three isoforms in mammalian cells...

that both the accumulation of hyaluronic acid (due to increased hyaluronan synthase levels and decreased HYAL levels) and the degradation of hyaluronic...

product. Hyaluronan synthase, that is a membrane-binding enzyme, is one of the factors that reduces the production of HA. Hyaluronan synthase limits hyaluronic...

Fawcett JW (September 2010). "In vitro modeling of perineuronal nets: hyaluronan synthase and link protein are necessary for their formation and integrity"...

promising target for cancer therapy. Hyaluronan synthase Hyaluronidase Toole, B.P. (October 1990). "Hyaluronan and its binding proteins, the hyaladherins"...

Michael J. (1996-09-20). "Functional Cloning of the cDNA for a Human Hyaluronan Synthase". Journal of Biological Chemistry. 271 (38): 23395–23399. doi:10...

Pollaschek C, Mueller MM, Stuhlmeier KM (June 2006). "Expression of hyaluronan synthase genes in umbilical cord blood stem/progenitor cells". Biochimica...

cells. Some chloroviruses contain chitin synthase (CHS) genes while some others contain hyaluronan synthase (HAS) genes, respectively triggering the formation...

erythematous mucinosis syndrome with an infiltration of factor XIIIa+ and hyaluronan synthase 2+ dermal dendrocytes". British Journal of Dermatology. 145 (1)....

phosphorylase EC 2.4.1.212: hyaluronan synthase EC 2.4.1.213: glucosylglycerol-phosphate synthase EC 2.4.1.214: glycoprotein 3-α-L-fucosyltransferase...

Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell...

glycocalyx such as syndecans, heparan sulphate, chondroitin sulphate and hyaluronan can be shed of the endothelial layer by enzymes. Hyaluronidase, hepararanse/heparinase...

cell walls of most fungi. Polymerized with glucuronic acid, it forms hyaluronan. GlcNAc has been reported to be an inhibitor of elastase release from...

extracellular matrix that are generated following tissue injury, such as hyaluronan fragments. Non-protein DAMPs include ATP, uric acid, heparin sulfate and...

oxide production. Proline rich Gla, PRRG2, has a Gla domain which binds hyaluronan and is associated with proteins present in the extracellular matrix involved...

(TGF-β1)-stimulated fibroblast to myofibroblast differentiation is mediated by hyaluronan (HA)-facilitated epidermal growth factor receptor (EGFR) and CD44 co-localization...

Anchoring Protein 13 ALDH18A1 ALDH18A1 Delta-1-pyrroline-5-carboxylate synthase ALG13 ALG13 ALG13, UDP-N-Acetylglucosaminyltransferase Subunit ALPK2 ALPK2/HAK...

of CD44, a surface molecule capable of internalizing iron bound to the hyaluronan complex. This alternative pathway, relying on CD44-mediated endocytosis...

negative regulation of lipid metabolic process sequestering of triglyceride hyaluronan biosynthetic process positive regulation of heterotypic cell-cell adhesion...

transcription 3 (STAT3) inhibits transcription of the inducible nitric oxide synthase gene by interacting with nuclear factor kappaB". Biochem. J. 367 (Pt 1):...

1998). "Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase". Proc...

neurotransmitters. Components of the extracellular matrix such as fibronectin and hyaluronan can also bind to such receptors (integrins and CD44, respectively). In...

2005). "Regulation of lung injury and repair by Toll-like receptors and hyaluronan". Nature Medicine. 11 (11): 1173–1179. doi:10.1038/nm1315. PMID 16244651...