Hyaluronidases are a family of enzymes that catalyse the degradation of hyaluronic acid. Karl Meyer classified these enzymes in 1971, into three distinct...
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Efgartigimod alfa/hyaluronidase, sold under the brand name Vyvgart Hytrulo, is a coformulation medication used for the treatment of generalized myasthenia...
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Pertuzumab/trastuzumab/hyaluronidase, sold under the brand name Phesgo, is a fixed-dose combination medication to treat adults with HER2-positive breast...
12 KB (966 words) - 07:37, 1 July 2024
Daratumumab/hyaluronidase, sold under the brand name Darzalex Faspro, is a fixed-dose combination medication for the treatment of adults with newly diagnosed...
11 KB (913 words) - 02:23, 5 November 2023
Trastuzumab/hyaluronidase, sold under the brand name Herceptin SC among others, is a fixed-dose combination medication for the treatment of HER2-overexpressing...
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Rituximab (redirect from Rituximab and hyaluronidase human)
Waldenström's macroglobulinemia, a type of NHL. Rituximab in combination with hyaluronidase human, sold under the brand names MabThera SC and Rituxan Hycela, is...
50 KB (4,348 words) - 03:50, 1 July 2024
Hyaluronidase deficiency is a condition caused by mutations in the HYAL1 gene, and is characterized by multiple soft-tissue masses.: 544 As hyaluronidase...
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primarily focused on its proprietary and patented recombinant human hyaluronidase enzyme, rHuPH20. The company's development pipeline is concentrated...
10 KB (1,016 words) - 17:35, 14 May 2024
sulphate and hyaluronan can be shed of the endothelial layer by enzymes. Hyaluronidase, hepararanse/heparinase, matrix and membrane-type matrix metalloproteases...
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acid)). Two published medical journals appear to show Hyaluronidase injections (Hyaluronidase is an enzyme used to dissolve hyaluronic acid which is...
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PMID 22050223. S2CID 207441558. Starr CR, Engleberg NC (January 2006). "Role of hyaluronidase in subcutaneous spread and growth of group A streptococcus". Infection...
40 KB (3,950 words) - 04:18, 20 May 2024
phospholipase A2, hyaluronidase and acid phosphatase. The three proteins in honeybee venom that are important allergens are phospholipase A2, hyaluronidase and acid...
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placental mammals, the acrosome contains degradative enzymes (including hyaluronidase and acrosin). These enzymes break down the outer membrane of the ovum...
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degraded by a family of enzymes called hyaluronidases. In humans, there are at least seven types of hyaluronidase-like enzymes, several of which are tumor...
50 KB (5,491 words) - 13:36, 29 June 2024
bruised. Hyaluronic acid "bruising" may be treated using injections of hyaluronidase enzyme around the location. Other common medication-specific side effects...
22 KB (2,581 words) - 08:38, 3 December 2023
fibrinogen to fibrin to cause clots which is important in skin infections. Hyaluronidase (also known as spreading factor) breaks down hyaluronic acid and helps...
114 KB (12,732 words) - 18:27, 23 May 2024
variety of enzymes which cause damage to host tissues. Enzymes include hyaluronidase, which breaks down the connective tissue component hyaluronic acid;...
15 KB (1,871 words) - 07:36, 25 March 2024
family of antibiotics that inhibits the hydrolysis of hyaluronic acid by hyaluronidase. It has been isolated from cultures of Streptomyces hyaluromycini. Harunari...
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instance, the figure to the right shows 3 spliceforms from the mouse hyaluronidase 3 gene. Comparing the exonic structure shown in the first line (green)...
62 KB (7,809 words) - 17:56, 21 May 2024
present in myasthenia gravis. It is also available coformulated with hyaluronidase. The most common side effects include respiratory tract infections,...
17 KB (1,326 words) - 07:06, 25 June 2024
affect the body in different ways. Almost all snake venom contains hyaluronidase, an enzyme that ensures rapid diffusion of the venom.: 243 Venomous...
151 KB (15,099 words) - 19:40, 3 July 2024
Acetoin Negative Acid Phosphatase Variable Alkaline Phosphatase Positive Hyaluronidase Negative β-D-glucosidase Positive Leucine aminopeptidase Positive Neuraminidase...
6 KB (551 words) - 03:52, 23 October 2023
subgenus of Vespula The venom of Vespula is mostly composed of antigen 5, hyaluronidase, and phospholipase. A high degree of similarity occurs between immunogenic...
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Hyaluronidase-2 is a multifunctional protein, previously thought to only possess acid-active hyaluronan-degrading enzymatic function. In humans it is...
10 KB (1,152 words) - 16:25, 1 February 2024
under the brand name Longidaze, is a conjugate of proteolytic enzyme hyaluronidase with high- molecular weight copolymer that forms a component of combination...
22 KB (1,707 words) - 19:18, 2 July 2024
Graafian follicle. For fertilization to occur, sperm cells rely on hyaluronidase (an enzyme found in the acrosome of spermatozoa) to disperse the corona...
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mucopolysaccharides E- Lysozymes Bacterial cell walls and mucopolysaccharides F- Hyaluronidase Hyaluronic acids, chondroitin sulfates H- Arylsulphatase Organic sulfates...
43 KB (4,709 words) - 17:51, 12 June 2024
female rats. Oleanolic acid is also used as standard for comparison of hyaluronidase, elastase and matrix-metalloproteinase-1 inhibition of other substances...
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Hyaluronidase-1 is an enzyme that in humans is encoded by the HYAL1 gene. This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly...
17 KB (2,078 words) - 10:05, 2 June 2024
the GalT initiates the acrosome reaction. This process releases the hyaluronidase that digests the matrix of hyaluronic acid in the vestments around the...
45 KB (5,197 words) - 08:18, 31 May 2024