• In biochemistry, hydrolases constitute a class of enzymes that commonly function as biochemical catalysts that use water to break a chemical bond: A −...
    5 KB (556 words) - 05:03, 27 August 2024
  • acid hydrolase is an enzyme that works best at acidic pHs. It is commonly located in lysosomes, which are acidic on the inside. Acid hydrolases may be...
    1 KB (139 words) - 04:35, 14 December 2023
  • Thumbnail for Gamma-glutamyl hydrolase
    Ghk. Gamma-glutamyl hydrolase is an enzyme that catalyses the following chemical reaction: Hydrolysis of a gamma-glutamyl bond This lysosomal or secreted...
    8 KB (982 words) - 11:50, 3 June 2024
  • Thumbnail for Epoxide hydrolase
    epoxide hydrolase (epoxide hydrolase 1, EH1, or mEH), soluble epoxide hydrolase (sEH, epoxide hydrolase 2, EH2, or cytoplasmic epoxide hydrolase), and the...
    19 KB (2,208 words) - 02:36, 23 September 2024
  • Thumbnail for Glycoside hydrolase
    In biochemistry, glycoside hydrolases (also called glycosidases or glycosyl hydrolases) are a class of enzymes which catalyze the hydrolysis of glycosidic...
    18 KB (1,932 words) - 08:37, 4 July 2024
  • In enzymology, a choloylglycine hydrolase (EC 3.5.1.24) is an enzyme that catalyzes the chemical reaction 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oylglycine...
    3 KB (341 words) - 13:32, 26 August 2023
  • 4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase (EC 3.6.1.57, PseG, UDP-6-deoxy-AltdiNAc hydrolase, Cj1312) is an enzyme with systematic name UDP-2...
    2 KB (174 words) - 16:12, 26 August 2023
  • The enzyme hydroxyacylglutathione hydrolase (EC 3.1.2.6, systematic name = S-(2-hydroxyacyl)glutathione hydrolase) catalyzes the following reaction:...
    1 KB (118 words) - 14:30, 26 August 2023
  • The enzyme dihydrocoumarin hydrolase (EC 3.1.1.35) catalyzes the reaction dihydrocoumarin + H2O ⇌ {\displaystyle \rightleftharpoons } melilotate This...
    1 KB (80 words) - 19:06, 10 July 2024
  • Thumbnail for Acyloxyacyl hydrolase
    The enzyme acyloxyacyl hydrolase (EC 3.1.1.77, AOAH) was discovered because it catalyzes the reaction 3-(acyloxy)acyl group of bacterial toxin + H2O =...
    3 KB (348 words) - 07:52, 2 January 2024
  • acylcarnitine hydrolase, HACH, carnitine ester hydrolase, palmitoylcarnitine hydrolase, palmitoyl-L-carnitine hydrolase, long-chain acyl-L-carnitine hydrolase, and...
    2 KB (142 words) - 12:57, 26 August 2023
  • The enzyme oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14) catalyzes the reaction an oleoyl-[acyl-carrier-protein] + H2O ⇌ {\displaystyle \rightleftharpoons...
    2 KB (195 words) - 20:53, 29 July 2024
  • Thumbnail for Fumarylacetoacetate hydrolase
    catabolism of the amino acid tyrosine in humans. Fumarylacetoacetate hydrolase (FAH) is a protein homodimer which cleaves fumarylacetoacetate at its...
    21 KB (2,536 words) - 22:56, 3 September 2024
  • Thumbnail for Alpha/beta hydrolase superfamily
    The alpha/beta hydrolase superfamily is a superfamily of hydrolytic enzymes of widely differing phylogenetic origin and catalytic function that share...
    4 KB (360 words) - 15:11, 30 July 2024
  • Thumbnail for FAAH2
    Fatty acid amide hydrolase 2 or FAAH2 is a member of the serine hydrolase family of enzymes. Fatty acid amide hydrolase 2 degrades endocannabinoids and...
    2 KB (164 words) - 03:45, 11 February 2024
  • Thumbnail for Fatty-acid amide hydrolase 1
    Fatty-acid amide hydrolase 1 (FAAH) is a member of the serine hydrolase family of enzymes. It was first shown to break down anandamide (AEA), an N-acylethanolamine...
    33 KB (3,460 words) - 01:21, 16 August 2024
  • The enzyme (S)-methylmalonyl-CoA hydrolase (EC 3.1.2.17) catalyzes the reaction (S)-methylmalonyl-CoA + H2O ⇌ {\displaystyle \rightleftharpoons } methylmalonate...
    1 KB (97 words) - 12:21, 26 August 2023
  • Thumbnail for Ubiquitin carboxy-terminal hydrolase L1
    Ubiquitin carboxy-terminal hydrolase L1 (EC 3.1.2.15, ubiquitin C-terminal hydrolase, UCH-L1) is a deubiquitinating enzyme. UCH-L1 is a member of a gene...
    21 KB (2,637 words) - 03:01, 26 November 2023
  • Thumbnail for Amylase
    amylopectin. They belong to glycoside hydrolase family 13 (https://www.cazypedia.org/index.php/Glycoside_Hydrolase_Family_13). Because it can act anywhere...
    23 KB (2,550 words) - 19:31, 17 October 2024
  • In enzymology, an allophanate hydrolase (EC 3.5.1.54) is an enzyme that catalyzes the chemical reaction allophanate + 3 H2O + H+ ⇌ {\displaystyle \rightleftharpoons...
    3 KB (240 words) - 13:05, 26 August 2023
  • Thumbnail for Nudix hydrolase
    NUDIX hydrolases are a superfamily of hydrolytic enzymes capable of cleaving nucleoside diphosphates linked to x (any moiety), hence their name. The reaction...
    4 KB (380 words) - 09:53, 10 September 2024
  • Thumbnail for Epoxide hydrolase 2
    Soluble epoxide hydrolase (sEH) is a bifunctional enzyme that in humans is encoded by the EPHX2 gene. sEH is a member of the epoxide hydrolase family. This...
    26 KB (3,080 words) - 15:18, 29 March 2024
  • Serine hydrolases are one of the largest known enzyme classes comprising approximately ~200 enzymes or 1% of the genes in the human proteome. A defining...
    3 KB (351 words) - 14:14, 19 March 2023
  • Rhamnogalacturonan hydrolase (EC 3.2.1.171, rhamnogalacturonase A, RGase A, RG-hydrolase) is an enzyme with systematic name rhamnogalacturonan...
    3 KB (309 words) - 12:13, 12 November 2023
  • Thumbnail for Lactase
    has been connected to Glu-1749, while Glu-1273 is the site of phlorizin hydrolase function. In humans, lactase is encoded by a single genetic locus on chromosome...
    22 KB (2,143 words) - 04:34, 23 September 2024
  • Thumbnail for Phosphodiesterase
    PDEs have different substrate specificities. Some are cAMP-selective hydrolases (PDE4, 7 and 8); others are cGMP-selective (PDE5, 6, and 9). Others can...
    15 KB (1,725 words) - 08:12, 7 August 2024
  • The enzyme ADP-dependent short-chain-acyl-CoA hydrolase (EC 3.1.2.18) catalyzes the reaction acyl-CoA + H2O ⇌ {\displaystyle \rightleftharpoons } CoA...
    2 KB (175 words) - 13:00, 26 August 2023
  • The enzyme chlorogenate hydrolase (EC 3.1.1.42) catalyzes the reaction chlorogenate + H2O ⇌ {\displaystyle \rightleftharpoons } caffeate + quinate This...
    1 KB (116 words) - 13:30, 26 August 2023
  • The enzyme phorbol-diester hydrolase (EC 3.1.1.51) catalyzes the reaction phorbol 12,13-dibutanoate + H2O ⇌ {\displaystyle \rightleftharpoons } phorbol...
    1 KB (101 words) - 15:21, 26 August 2023
  • 2.1.138, GcoA) is an enzyme with systematic name (+)-β-caryophyllene hydrolase (cyclizing, (+)-caryolan-1-ol-forming). This enzyme catalyses the following...
    1 KB (113 words) - 12:15, 26 August 2023