• In chemistry, hydroxylation can refer to: (i) most commonly, hydroxylation describes a chemical process that introduces a hydroxyl group (−OH) into an...
    9 KB (1,058 words) - 07:42, 20 June 2024
  • Thumbnail for Phenylacetone
     ... The location of the p-hydroxylation and β-hydroxylation reactions is important in species where aromatic hydroxylation of amphetamine is the predominant...
    8 KB (1,749 words) - 15:30, 13 October 2024
  • The Woodward cis-hydroxylation (also known as the Woodward reaction) is the chemical reaction of alkenes with iodine and silver acetate in wet acetic...
    2 KB (202 words) - 22:30, 27 September 2024
  • Thumbnail for Lisdexamfetamine
     ... The location of the p-hydroxylation and β-hydroxylation reactions is important in species where aromatic hydroxylation of amphetamine is the predominant...
    45 KB (14,062 words) - 20:53, 26 October 2024
  • Thumbnail for Oxaziridine
    reagents in organic chemistry for a variety of oxidations, including alpha hydroxylation of enolates, epoxidation and aziridination of olefins, and other heteroatom...
    26 KB (2,506 words) - 01:08, 14 September 2024
  • The Milas hydroxylation is an organic reaction converting an alkene to a vicinal diol, and was developed by Nicholas A. Milas in the 1930s. The cis-diol...
    6 KB (698 words) - 17:41, 11 February 2023
  • Thumbnail for Cytochrome P450
    fatty acids, xenobiotics, and participate in many biosyntheses. By hydroxylation, CYP450 enzymes convert xenobiotics into hydrophilic derivatives, which...
    15 KB (1,669 words) - 15:00, 1 October 2024
  • benzene, such as halogenation, cyanation, trifluoromethylation, and hydroxylation. The reaction was discovered in 1884 by Swiss chemist Traugott Sandmeyer...
    16 KB (1,738 words) - 18:24, 22 October 2024
  • Thumbnail for Phenylpropanolamine
     ... The location of the p-hydroxylation and β-hydroxylation reactions is important in species where aromatic hydroxylation of amphetamine is the predominant...
    52 KB (5,581 words) - 23:14, 18 October 2024
  • Thumbnail for Hydroxylation of estradiol
    The hydroxylation of estradiol is one of the major routes of metabolism of the estrogen steroid hormone estradiol. It is hydroxylated into the catechol...
    14 KB (1,786 words) - 11:40, 10 March 2023
  • Thumbnail for Collagen
    this vitamin results in impaired collagen synthesis and scurvy. These hydroxylation reactions are catalyzed by two different enzymes: prolyl 4-hydroxylase...
    69 KB (7,689 words) - 01:02, 14 October 2024
  • Thumbnail for Aldosterone synthase
    The enzyme catalyzes sequential hydroxylations of the steroid angular methyl group at C18 after initial 11β-hydroxylation (the enzyme has steroid 18-hydroxylase...
    21 KB (2,347 words) - 03:26, 2 November 2024
  • Thumbnail for 4-Hydroxyphenylacetone
     ... The location of the p-hydroxylation and β-hydroxylation reactions is important in species where aromatic hydroxylation of amphetamine is the predominant...
    2 KB (1,191 words) - 16:13, 21 October 2024
  • Thumbnail for Alcohol (chemistry)
    alcohols are produced by hydroxylation, i.e., the installation of a hydroxy group using oxygen or a related oxidant. Hydroxylation is the means by which...
    35 KB (3,839 words) - 01:43, 2 November 2024
  • Thumbnail for Hydroxyproline
    group attached to the gamma carbon atom. Hydroxyproline is produced by hydroxylation of the amino acid proline by the enzyme prolyl hydroxylase following...
    10 KB (976 words) - 12:04, 8 October 2024
  • Thumbnail for 4-Hydroxyamphetamine
     ... The location of the p-hydroxylation and β-hydroxylation reactions is important in species where aromatic hydroxylation of amphetamine is the predominant...
    15 KB (2,283 words) - 10:05, 21 October 2024
  • Thumbnail for Silver acetate
    acetate in combination with iodine forms the basis of the Woodward cis-hydroxylation. This reaction selectively converts an alkene into a cis-diol. In the...
    9 KB (850 words) - 04:01, 27 December 2023
  • Thumbnail for P-Hydroxynorephedrine
    to one patient indicates that the hydroxylation occurs in body tissues. ... a major portion of the β-hydroxylation of hydroxyamphetamine occurs in non-adrenal...
    3 KB (1,230 words) - 14:24, 21 September 2024
  • aromatic ring undergoes an intramolecular migration primarily during a hydroxylation reaction. This process is also known as a 1,2-hydride shift. These shifts...
    2 KB (228 words) - 10:23, 11 August 2024
  • Thumbnail for Methocarbamol
    is not hydrolyzed metabolically; its metabolism is by Phase I ring hydroxylation and O-demethylation, followed by Phase II conjugation. All the major...
    26 KB (2,353 words) - 05:32, 30 September 2024
  • Thumbnail for Adrenal cortex
    Progesterone → (hydroxylation at C21) → 11-Deoxycorticosterone → (two further hydroxylations at C11 and C18) → Aldosterone Progesterone → (hydroxylation at C17)...
    13 KB (1,476 words) - 20:50, 17 July 2024
  • Thumbnail for Corticosteroid
    corticosterone). These enzymes are nearly identical (they share 11β-hydroxylation and 18-hydroxylation functions), but aldosterone synthase is also able to perform...
    42 KB (4,208 words) - 15:07, 3 November 2024
  • Thumbnail for Phenylalanine
    (1983-03-14). "Stereospecificity of phenylalanine plasma kinetics and hydroxylation in man following oral application of a stable isotope-labelled pseudo-racemic...
    28 KB (2,386 words) - 21:26, 25 July 2024
  • Thumbnail for Trazodone
    Trazodone is known to be extensively metabolized by the liver via hydroxylation, N-oxidation, and N-dealkylation. Several metabolites of trazodone have...
    115 KB (10,960 words) - 16:04, 2 November 2024
  • Thumbnail for Vitamin D
    the skin is biologically inactive. It becomes active by two enzymatic hydroxylation steps, the first occurring in the liver and the second in the kidneys...
    163 KB (17,774 words) - 22:30, 2 November 2024
  • Thumbnail for Methanol
    A. Friesner; Stephen J. Lippard (2003). "Mechanistic Studies on the Hydroxylation of Methane by Methane Monooxygenase". Chem. Rev. 103 (6): 2385–2420...
    55 KB (5,310 words) - 10:24, 9 October 2024
  • Thumbnail for Calcifediol
    (abbreviated 25(OH)D3), is a form of vitamin D produced in the liver by hydroxylation of vitamin D3 (cholecalciferol) by the enzyme vitamin D 25-hydroxylase...
    22 KB (2,094 words) - 03:57, 19 October 2024
  • Thumbnail for Methoxsalen
    This is then followed by a hydroxylation catalyzed by the enzyme marmesin synthase to yield marmesin. Another hydroxylation is catalyzed by psoralen synthase...
    10 KB (756 words) - 00:28, 16 October 2024
  • Thumbnail for Norethisterone
    metabolism.[citation needed] Norethisterone is partially metabolized via hydroxylation by CYP3A4, and inhibitors and inducers of CYP3A4 can significantly alter...
    95 KB (9,422 words) - 21:09, 24 October 2024
  • Thumbnail for Metoprolol
    intestines. Metoprolol undergoes extensive metabolism in the liver, mainly α-hydroxylation and O-demethylation through various cytochrome P450 enzymes such as...
    31 KB (2,632 words) - 22:56, 26 October 2024