Hypophosphatasia (/ˌhaɪpoʊˈfɒsfeɪtˌeɪʒə/; also called deficiency of alkaline phosphatase, phosphoethanolaminuria, or Rathbun's syndrome; sometimes abbreviated...

the treatment of people with perinatal/infantile- and juvenile-onset hypophosphatasia. The most common side effects include injection site reactions, hypersensitivity...

nocturnal hemoglobinuria (PNH); asfotase alfa (Strensiq), used to treat hypophosphatasia; sebelipase alfa (Kanuma), used to treat lysosomal acid lipase deficiency...

state. This enzyme has been linked directly to a disorder known as hypophosphatasia, a disorder that is characterized by low serum ALP and undermineralised...

particularly relevant to the osteomalacia and odontomalacia observed in hypophosphatasia (HPP) and X-linked hypophosphatemia (XLH). The most common cause of...

syndrome) Fracture Giant cell tumor of bone Greenstick fracture Gout Hypophosphatasia Hereditary multiple exostoses Klippel–Feil syndrome Metabolic bone...

of cartilage glycosaminoglycans Hyperparathyroidism Hemochromatosis Hypophosphatasia Hypomagnesemia Hydroxyapatite deposition: Tissue damage Hyperparathyroidism...

renal osteodystrophy, osteogenesis imperfecta, fibrous dysplasia, and hypophosphatasia. Looser zones are named after Emil Looser, a Swiss physician. A band...

It is a feature of conditions such as cleidocranial dysplasia and hypophosphatasia. Ireland R (25 March 2010). A Dictionary of Dentistry. Oxford University...

vitamin D or calcium Diseases causing soft bones in infants, like hypophosphatasia or hypophosphatemia, can also lead to rickets. Strontium is allied...

conditions or diseases may lead to reduced levels of alkaline phosphatase: Hypophosphatasia, a genetic disorder Women receiving estrogen therapy for menopausal...

"A Case of Spondylodysplastic Ehlers–Danlos Syndrome With Comorbid Hypophosphatasia". AACE Clinical Case Reports. 8 (6): 255–258. doi:10.1016/j.aace.2022...

wasting, both cause osteomalacia and odontomalacia. For both XLH and hypophosphatasia, inhibitor-enzyme pair relationships function to regulate mineralization...

syndrome Cardio-facio-cutaneous syndrome Catel-Manzke syndrome Childhood hypophosphatasia Chondrodysplasia with joint dislocations, gPAPP type Cloverleaf skull...

"Kinky-hair" Menke's syndrome Cleidocranial dysostosis Hypothyroidism and hypophosphatasia Otopalatodigital syndrome Primary acro-osteolysis Down syndrome Wormian...

PMID 34307793. Nunes ME (1993). "Hypophosphatasia". GeneReviews®. University of Washington, Seattle. PMID 20301329. "Hypophosphatasia Case Studies: Dangers of...

syndrome, Heimler syndrome & Ellis-Van Creveld syndrome, Down syndrome, Hypophosphatasia, Regional odontodysplasia, Cleft lip and palate, Vitamin D-resistant...

is found in hypothyroidism, pernicious anemia, zinc deficiency, and hypophosphatasia. ALP activity is significantly increased in the third trimester of...

hyperparathyroidism Arthritis Pseudogout Wilson disease Hemochromatosis Ochronosis Hypophosphatasia Hypothyroidism Hyperoxalemia Acromegaly Gitelman syndrome Chondrocalcinosis...

and to confirm an elevated level of vitamin B6 with an absence of hypophosphatasia. Examination does not typically show signs of a motor deficit, dysfunction...

deficiency, PLP binding protein deficiency, hyperprolinaemia type II and hypophosphatasia) can trigger vitamin B6 deficiency-dependent epileptic seizures in...

stature Hypoparathyroidism X linked Hypoparathyroidism Hypophosphatasia, infantile Hypophosphatasia Hypophosphatemic rickets Hypopigmentation oculocerebral...

C1868570)". www.ncbi.nlm.nih.gov. Retrieved 2023-07-05. "Childhood hypophosphatasia (Concept Id: C0220743) - MedGen - NCBI". www.ncbi.nlm.nih.gov. Retrieved...

malnutrition, as well as rare skeletal syndromes such as Bruck syndrome, hypophosphatasia, geroderma osteodysplasticum, and Ehlers–Danlos syndrome.: 1513 : 253–256 ...

epoxidase, an enzyme Hypokalemic periodic paralysis, a muscle disease Hypophosphatasia, a bone disease Hypoxia preconditioned plasma Hardy-Pomeau-Pazzis model...

Asfotase alfa Alexion Pharmaceuticals perinatal/infantile/childhood hypophosphatasia Osimertinib AstraZeneca EGFR-positive NSCLC Daratumumab Janssen Biotech...

Xuriden Orotic aciduria Wellstat Therapeutics Rare pediatric Strensiq Hypophosphatasia Alexion Pharmaceuticals Rare pediatric Kanuma Lysosomal acid lipase...

particularly relevant to the osteomalacia and odontomalacia observed in hypophosphatasia and X-linked hypophosphatemia. Mutation of PHEX leads to X-linked hypophosphatemia...

particularly relevant to the osteomalacia and odontomalacia observed in hypophosphatasia and X-linked hypophosphatemia. Along with its role in the regulation...

275.3 Disorders of phosphorus metabolism Familial hypophosphatemia Hypophosphatasia 275.4 Disorders of calcium metabolism 275.41 Hypocalcemia 275.42 Hypercalcemia...