Immune tolerance, also known as immunological tolerance or immunotolerance, refers to the immune system's state of unresponsiveness to substances or tissues...

Immune tolerance in pregnancy or maternal immune tolerance is the immune tolerance shown towards the fetus and placenta during pregnancy. This tolerance...

disease by activating or suppressing the immune system. Immunotherapies designed to elicit or amplify an immune response are classified as activation immunotherapies...

healthy individuals, immune tolerance prevents the immune system from attacking the body's own cells. When this process fails, the immune system may produce...

rendered non-reactive to self Immune tolerance in pregnancy or gestational/maternal immune tolerance Low frustration tolerance, a concept in Rational Emotive...

significant impact on the promotion of central and peripheral immune tolerance. In central tolerance, dendritic cells are present within the thymus, or the location...

immunology, peripheral tolerance is the second branch of immunological tolerance, after central tolerance. It takes place in the immune periphery (after T...

autoreactive lymphocytes, tolerance ensures that the immune system does not attack self peptides. Lymphocyte maturation (and central tolerance) occurs in primary...

may stem from the maternal immune system's response to the placenta, specifically a lack of established immunological tolerance in pregnancy. Endothelial...

from immune privileged regions have been found to interact with T cells in an unusual way: inducing tolerance of normally rejected stimuli. Immune privilege...

autoaggressive immune responses in the immune system. Tolerance can also be differentiated into "central" and "peripheral" tolerance, on whether or not...

The adaptive immune system, also known as the acquired immune system, or specific immune system is a subsystem of the immune system that is composed of...

absence of them) between the immune system and components related to the reproductive system, such as maternal immune tolerance towards the fetus, or immunological...

trials attempting to induce immune tolerance by vaccination with insulin, GAD65, and various short peptides targeted by immune cells during type 1 diabetes;...

induce tolerance through immunotherapy) on Treg function and epigenetic changes. This research led to novel findings on markers of immune tolerance in clinical...

associated with the X chromosome. It contains sex and immune-related genes responsible for immune tolerance. A higher incidence of thyroid autoimmunity was...

MHC class II and for his seminal studies in the fields of transplant immune tolerance and xenotransplantation. David Sachs graduated summa cum laude in organic...

can lead to common complaints, such as palpitations, decreased exercise tolerance, and dizziness. Uterine enlargement beyond 20 weeks' size can compress...

Immune checkpoints are regulators of the immune system. These pathways are crucial for self-tolerance, which prevents the immune system from attacking...

T cells, are a subpopulation of T cells that modulate the immune system, maintain tolerance to self-antigens, and prevent autoimmune disease. Treg cells...

their T-cell receptor, or TCR. Immune tolerance is maintained by central and peripheral tolerance. During central tolerance, T-cells are selected in the...

maintaining immune tolerance and preventing excessive inflammatory response in the gut mucosa. Due to its adaptability and interaction with the host immune and...

role in central tolerance. Clonal deletion can help protect individuals against autoimmunity, which is when an organism produces and immune response on its...

allergies by properly tuning the immune system. In particular, a lack of such exposure is thought to lead to poor immune tolerance. The time period for exposure...

differentiating to Treg cells and preventing a fetal immune response to maternal antigens. This expanded immune tolerance persists in both mother and offspring after...

as well, being intimately involved in wound healing, angiogenesis, immune tolerance, defense against pathogens, and vascular permeability in brain tumors...

induction of peripheral lymphocyte tolerance. When an individual is in a state of anergy, it signifies that their immune system is incapable of mounting...

Patients then come to clinical attention when this tumor immune response breaks immune tolerance and begins to attack the normal tissue expressing that...

regulator), which is located on chromosome 21 and normally confers immune tolerance. APS-1 tends to cause severe symptoms. These are present from early...

to immunology. He won a Nobel Prize in 1960 for predicting acquired immune tolerance. He also developed the theory of clonal selection. Burnet received...