Indoline is an aromatic heterocyclic organic compound with the chemical formulation C8H9N. It has a bicyclic structure, consisting of a six-membered benzene...
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VEGFR-2 inhibitor, also known as kinase insert domain receptor(KDR) inhibitor, are tyrosine kinase receptor inhibitors that reduce angiogenesis or lymphangiogenesis...
51 KB (4,735 words) - 08:15, 2 January 2024
Bebbington D, Benwell KR, Bickerdike MJ, Davidson JE, et al. (2004). "Indoline derivatives as 5-HT(2C) receptor agonists". Bioorg. Med. Chem. Lett. 14...
105 KB (9,933 words) - 15:41, 7 September 2024
Ibutamoren (category Indolines)
Ibutamoren (INNTooltip International Nonproprietary Name) (developmental code names MK-677, MK-0677, LUM-201, L-163,191; former tentative brand name Oratrope)...
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formula C8H9N (molar mass: 119.167 g/mol) may refer to: 4,7-Dihydroisoindole Indoline Isoindoline Azonine 2,3-Cyclopentapyridine 3,4-Cyclopentapyridine This...
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five-membered nitrogen-containing ring. The compound's structure is similar to indoline except that the nitrogen atom is in the 2 position instead of the 1 position...
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Oxindole (category Indolines)
nitrogen-containing ring. Oxindole is a modified indoline with a substituted carbonyl at the second position of the 5-member indoline ring. Classified as a cyclic amide...
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Indigo dye (category Indolines)
Indigo dye is an organic compound with a distinctive blue color. Indigo is a natural dye extracted from the leaves of some plants of the Indigofera genus...
41 KB (3,926 words) - 09:48, 10 June 2024
having the indole core flipped and/or replaced with related cores such as indoline, indazole, benzothiophene, or benzofuran. These similarly are primarily...
70 KB (1,747 words) - 07:02, 8 September 2024
Ropinirole (category Indolines)
Ropinirole, sold under the brand name Requip among others, is a medication used to treat Parkinson's disease (PD) and restless legs syndrome (RLS). It...
15 KB (1,309 words) - 07:27, 13 May 2024
6-Chloro-5-ethoxy-N-(pyridin-2-yl)indoline-1-carboxamide (CEPC) is a drug which acts as a potent and selective antagonist for the serotonin 5-HT2C receptor...
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GuglielmettiComparative photodegradation study between spiro[indoline-oxazine] and spiro[indoline-pyran] derivatives in solution, J. Photochem. Photobiol....
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Silodosin (category Indolines)
1-(3-hydroxypropyl)-5-[(2R)-({2-[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl}amino)propyl]indoline-7-carboxamide CAS Number 160970-54-7 N PubChem CID 5312125 IUPHAR/BPS 493...
15 KB (1,151 words) - 07:52, 8 May 2024
8a-hexahydropyrrolo-[2,3-b]-indole-2-carboxylic acid (peak C) and 2-(2-hydroxy indoline)-tryptophan (peak FF). These were characterized using accurate mass LC–MS...
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structurally derived from 1-benzofuran, 2,3-dihydro-1-benzofuran, 1H-indole, indoline, 1H-indene, or indane by substitution in the 6-membered ring with a 2-ethylamino...
49 KB (3,955 words) - 09:31, 8 May 2024
Indoles are susceptible to hydrogenation of the imine subunit to give indolines. Indole-3-butyric acid Indole test Isoindole Isoindoline Skatole (3-methylindole)...
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alkyl hydrocarbon tails on each on the nitrogen (Position 1) of the two indoline rings, a conjugated 3-carbon bridge connecting the 2nd positions (Carbon)...
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nitrogen-containing heterocycles Pyridines, quinolines, benzoquinolines, acridines, indolines, and carbazoles 3.0–8.0% Sulfur-containing heterocycles Benzothiophenes...
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building block, construction of the indoline spiroaminal via cautious stepwise oxidations with cyclizations from the indoline, assembly of (Z)-dehydrohistidine...
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Bebbington D, Benwell KR, Bickerdike MJ, Davidson JE, et al. (May 2004). "Indoline derivatives as 5-HT(2C) receptor agonists". Bioorganic & Medicinal Chemistry...
38 KB (3,089 words) - 18:45, 8 September 2024
(the quinuclidonium salt and a reference amine such as diethylamine or indoline) are introduced into a mass spectrometer. The relative basicity is then...
5 KB (583 words) - 13:03, 19 June 2024
Isatin (category Indolines)
1937–1943. doi:10.1055/s-0034-1380517. Wei, W.T. (2018). "Synthesis of Indoline-2,3-diones by Radical Coupling of Indolin-2-ones with tert-Butyl Hydroperoxide"...
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(January 2011). "X-ray and NMR crystallography in an enzyme active site: the indoline quinonoid intermediate in tryptophan synthase". Journal of the American...
17 KB (2,249 words) - 23:16, 29 November 2023
Culinary Federation (ACF) certification 6-Chloro-5-ethoxy-N-(pyridin-2-yl)indoline-1-carboxamide, a pharmaceutical Circular Electron Positron Collider, a...
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length of time of its storage. Another group of spiropyrans which contain indoline or nitrogen heterocycles and the indolinospirothiapyrans found their application...
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Zhou, Y. G. (2011). "An Enantioselective Approach to 2,3-Disubstituted Indolines through Consecutive Brønsted Acid/Pd-Complex-Promoted Tandem Reactions"...
64 KB (6,355 words) - 10:03, 21 August 2024
8a,9-tetrahydrospiro[5a,9a-(epiminomethano)cyclopenta[f]indolizine-7,2'-indoline]-3',5,10(1H,6H,8H)-trione Brevianamide B: (2′S,5aR,8aS,9aR)-8,8-Dimethyl-2...
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known. The C21H22N2O2 strychnine molecule contains 7 rings including an indoline system. It has a tertiary amine group, an amide, an alkene and an ether...
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2',3,10-tetraoxo-spiro[4,5,6,7-tetrahydropyrido[1,2-f]pteridine-8,3'-indoline]-7-carboxylate. It is insoluble in organic solvents and has very low solubility...
10 KB (1,089 words) - 10:10, 27 December 2023
followed again by a retro Diels-Alder in situ, to afford an indoline product. This indoline is a converted into either PDE-I or PDE-II in a few synthetic...
26 KB (2,637 words) - 20:27, 12 July 2024