Interferons (IFNs, /ˌɪntərˈfɪərɒn/ IN-tər-FEER-on) are a group of signaling proteins made and released by host cells in response to the presence of several...
62 KB (7,065 words) - 05:17, 28 June 2024
Interferon beta-1a (also interferon beta 1-alpha) is a cytokine in the interferon family used to treat multiple sclerosis (MS). It is produced by mammalian...
32 KB (2,851 words) - 23:22, 16 August 2024
The type-I interferons (IFN) are cytokines which play essential roles in inflammation, immunoregulation, tumor cells recognition, and T-cell responses...
24 KB (2,932 words) - 03:26, 14 June 2024
Interferon gamma (IFNG or IFN-γ) is a dimerized soluble cytokine that is the only member of the type II class of interferons. The existence of this interferon...
56 KB (6,483 words) - 07:29, 6 November 2024
Pegylated interferon (PEG-IFN) is a class of medication that includes three different drugs as of 2012: Pegylated interferon-alpha-2a Pegylated interferon-alpha-2b...
2 KB (185 words) - 07:35, 11 September 2023
Interferon alfa (INN) or HuIFN-alpha-Le, trade name Multiferon, is a pharmaceutical drug composed of natural interferon alpha (IFN-α), obtained from the...
7 KB (662 words) - 22:43, 14 September 2024
IRF3 (redirect from Interferon regulatory factor-3)
Interferon regulatory factor 3, also known as IRF3, is an interferon regulatory factor. IRF3 is a member of the interferon regulatory transcription factor...
12 KB (1,493 words) - 01:36, 11 December 2023
Stimulator of interferon genes (STING), also known as transmembrane protein 173 (TMEM173) and MPYS/MITA/ERIS is a protein that in humans is encoded by...
24 KB (2,748 words) - 06:07, 21 September 2024
An interferon-stimulated gene (ISG) is a gene that can be expressed in response to stimulation by interferon. Interferons bind to receptors on the surface...
13 KB (1,530 words) - 20:52, 19 April 2024
Interferon alfa-2b is an antiviral or antineoplastic drug. It is a recombinant form of the protein Interferon alpha-2 that was originally sequenced and...
10 KB (793 words) - 08:11, 15 September 2024
Interferon-induced transmembrane protein 2 is a protein that in humans is encoded by the IFITM2 gene. IFITM1 is a member of the IFITM family (Interferon-induced...
3 KB (394 words) - 23:45, 2 December 2023
signaling as immunomodulating agents. Cytokines include chemokines, interferons, interleukins, lymphokines, and tumour necrosis factors, but generally...
35 KB (3,981 words) - 23:55, 21 November 2024
Peginterferon alfa-2a (redirect from Pegylated interferon-alpha-2a)
Pegylated interferon alfa-2a, sold under the brand name Pegasys among others, is medication used to treat hepatitis C and hepatitis B. For hepatitis C...
11 KB (905 words) - 00:05, 5 September 2024
IRF8 (redirect from Interferon Consensus Sequence-binding protein)
Interferon regulatory factor 8 (IRF8) also known as interferon consensus sequence-binding protein (ICSBP), is a protein that in humans is encoded by the...
19 KB (2,321 words) - 13:56, 24 December 2023
Interferon beta-1b is a cytokine in the interferon family used to treat the relapsing-remitting and secondary-progressive forms of multiple sclerosis (MS)...
13 KB (1,292 words) - 19:17, 6 April 2024
Interferon regulatory factors (IRF) are proteins which regulate transcription of interferons (see regulation of gene expression). Interferon regulatory...
10 KB (1,098 words) - 23:10, 30 March 2024
ISG15 (redirect from Interferon-stimulated gene 15)
Interferon-stimulated gene 15 (ISG15) is a 17 kDa secreted protein that in humans is encoded by the ISG15 gene. ISG15 is induced by type I interferon...
22 KB (2,575 words) - 17:56, 23 October 2024
IRF7 (redirect from Interferon regulatory factor-7)
Interferon regulatory factor 7, also known as IRF7, is a member of the interferon regulatory factor family of transcription factors. IRF7 encodes interferon...
11 KB (1,417 words) - 07:42, 7 July 2023
Interferon alfacon-1 is a recombinant synthetic type I interferon used for the treatment of hairy cell leukemia, malignant melanoma and AIDS-related Kaposi's...
2 KB (30 words) - 16:41, 12 November 2023
Interferon alpha-n3 (Alferon-N) is a medication consisting of purified natural human interferon alpha proteins used for the treatment of genital warts...
3 KB (28 words) - 11:55, 15 September 2024
Plasmacytoid dendritic cell (redirect from Interferon Producing Cells)
type of immune cell that are known to secrete large quantities of type 1 interferon (IFNs) in response to a viral infection. They circulate in the blood and...
14 KB (1,833 words) - 05:36, 27 December 2023
The interferon-α/β receptor (IFNAR) is a virtually ubiquitous membrane receptor which binds endogenous type I interferon (IFN) cytokines. Endogenous human...
24 KB (2,617 words) - 19:43, 7 August 2022
Interferon-γ release assays (IGRA) are medical tests used in the diagnosis of some infectious diseases, especially tuberculosis. Interferon-γ (IFN-γ)...
4 KB (583 words) - 20:36, 8 July 2024
Type II cytokine receptor (redirect from Interferon receptor)
respond to a select group of cytokines including interferon type I, interferon type II, interferon type III. and members of the interleukin-10 family...
6 KB (616 words) - 18:29, 7 June 2023
The type III interferon group is a group of anti-viral cytokines, that consists of four IFN-λ (lambda) molecules called IFN-λ1, IFN-λ2, IFN-λ3 (also known...
12 KB (1,397 words) - 15:30, 12 June 2024
The interferon-gamma receptor (IFNGR) protein complex is the heterodimer of two chains: IFNGR1 and IFNGR2. It binds interferon-γ, the sole member of interferon...
8 KB (870 words) - 23:14, 28 May 2024
Interleukin-28 receptor (redirect from Interferon-lambda receptor)
3 interferons, interleukin-28 A (Interferon lambda 1), Interleukin-28B (Interferon lambda 2), interleukin 29 (Interferon lambda 3) and interferon lambda...
10 KB (1,126 words) - 20:57, 24 June 2021
Interferon tau (IFNτ, IFNT) is a Type I interferon made of a single chain of amino acids. IFN-τ was first discovered in ruminants as the signal for the...
15 KB (1,827 words) - 13:36, 23 May 2024
of interferon gamma and TNF.[citation needed] CD4+ T-helper cells may be differentiated into two main categories: TH1 cells which produce interferon gamma...
14 KB (1,377 words) - 16:49, 20 November 2024
Interferon lambda 4 (gene symbol: IFNL4) is one of the most recently discovered human genes and the newest addition to the interferon lambda protein family...
53 KB (6,064 words) - 16:19, 13 August 2024