Irinotecan, sold under the brand name Camptosar among others, is an anti-cancer medication used to treat colon cancer and small cell lung cancer. For colon...

active metabolite of irinotecan (an analog of camptothecin - a topoisomerase I inhibitor) but has 1000 times more activity than irinotecan itself. In vitro...

which incorporates into the DNA molecule and stops synthesis; and IRI – irinotecan (Camptosar), a topoisomerase inhibitor, which prevents DNA from uncoiling...

effectiveness to prevent diarrhea in cancer patients who have received irinotecan. It can interfere with the absorption of some medications, and lead to...

Europe during the Cold War. Atropine has been observed to prevent or treat irinotecan induced acute diarrhea. Adverse reactions to atropine include ventricular...

colorectal cancer who received prior fluoropyrimidine-, oxaliplatin-, and irinotecan-based chemotherapy, an anti-VEGF therapy, and, if RAS wild-type and medically...

(Belotecan Camptothecin Cositecan† Etirinotecan pegol† Exatecan Gimatecan Irinotecan# Lurtotecan‡ Rubitecan‡ Silatecan§ Topotecan) II Podophyllum (Etoposide#...

interferes with both of these processes. Two topoisomerase I inhibitors, irinotecan and topotecan, are semi-synthetically derived from camptothecin, which...

under investigation for or used as drugs for cancer treatment, including irinotecan, topotecan, rubitecan. C. acuminata also contains the chemical compounds...

(Belotecan Camptothecin Cositecan† Etirinotecan pegol† Exatecan Gimatecan Irinotecan# Lurtotecan‡ Rubitecan‡ Silatecan§ Topotecan) II Podophyllum (Etoposide#...

Romidepsin Vorinostat Zabadinostat Belotecan Camptothecin Exatecan Gimatecan Irinotecan Topotecan Etoposide Teniposide Tafluposide Bortezomib Erlotinib Gefitinib...

chemotherapy is given the FOLFIRINOX regimen containing fluorouracil, irinotecan, oxaliplatin and leucovorin has been shown to extend survival beyond traditional...

chemotherapeutic – cisplatin or carboplatin – combined with either etoposide or irinotecan. This is typically combined with thoracic radiation therapy – 45 Gray...

loperamide also include chemotherapy-induced diarrhea, especially related to irinotecan use. Loperamide should not be used as the primary treatment in cases of...

chemotherapy regimen for rare clear-cell cancers is also under investigation: irinotecan combined with cisplatin. PARP inhibitors have also shown promise in early...

(5-FU), up to 40% get mucositis, and 10–15% get grade 3–4 oral mucositis. Irinotecan is associated with severe GI mucositis in over 20% of patients. Seventy-five...

cisplatin, epirubicin, etoposide, docetaxel, oxaliplatin, capecitabine, or irinotecan. The TNM staging system is also used. In a study of open-access endoscopy...

IOHEXOL 255. IOPAMIDOL 4 256. IOMEPROL 257. IOPROMIDE 258. IRBESARTAN 259. IRINOTECAN HYDROCHLORIDE 260. IRON PREPARATION FOR PARENTERAL USE 261. ISEPAMICINE...

(Belotecan Camptothecin Cositecan† Etirinotecan pegol† Exatecan Gimatecan Irinotecan# Lurtotecan‡ Rubitecan‡ Silatecan§ Topotecan) II Podophyllum (Etoposide#...

for a small number of drugs that are very toxic to the intestine (e.g. irinotecan), these molecules which would not otherwise be very toxic can become so...

Chemotherapy drugs for this condition may include capecitabine, fluorouracil, irinotecan, oxaliplatin and UFT. The drugs capecitabine and fluorouracil are interchangeable...

such as irinotecan. This effect is derived from the microbiome-encoded β-glucuronidase enzymes which recover the active form of the irinotecan causing...

with severe diarrhea and neutropenia in patients who are treated with irinotecan, which is metabolized by UGT1A1. While paracetamol (acetaminophen) is...

chlorambucil, estramustine, etoposide, flutamide, idarubicin, ifosfamide, irinotecan, ixabepilone, letrozole, lomustine, megestrol, mitomycin, mitoxantrone...

(Belotecan Camptothecin Cositecan† Etirinotecan pegol† Exatecan Gimatecan Irinotecan# Lurtotecan‡ Rubitecan‡ Silatecan§ Topotecan) II Podophyllum (Etoposide#...

include a combination of chemotherapy (paclitaxel and carboplatin or irinotecan plus cisplatin) and surgical resection in ovarian clear-cell carcinoma;...

(Belotecan Camptothecin Cositecan† Etirinotecan pegol† Exatecan Gimatecan Irinotecan# Lurtotecan‡ Rubitecan‡ Silatecan§ Topotecan) II Podophyllum (Etoposide#...

ways: Rotor syndrome may exacerbate toxic side effects of the medication irinotecan. Rotor syndrome is caused by mutations in two proteins responsible for...

which incorporates into the DNA molecule and stops DNA synthesis; IRIN – irinotecan (Camptosar), a topoisomerase inhibitor, which prevents DNA from uncoiling...

(Belotecan Camptothecin Cositecan† Etirinotecan pegol† Exatecan Gimatecan Irinotecan# Lurtotecan‡ Rubitecan‡ Silatecan§ Topotecan) II Podophyllum (Etoposide#...