• Thumbnail for KV4
    KV4 is a tomb in the Valley of the Kings (Egypt). The tomb was initiated for the burial of Ramesses XI but it is likely that its construction was abandoned...
    9 KB (1,162 words) - 18:16, 8 July 2023
  • toxin selectively inhibits Kv4.2 voltage-gated potassium channels by acting as a gating modifier. TLTx is part of the family of Kv4-specific tarantula toxins...
    4 KB (530 words) - 02:26, 29 November 2023
  • Thumbnail for Repolarization
    Kv3 and Kv4. The Kv1 channel primarily influences the repolarization of the axon. The Kv2 channel is characteristically activated slower. The Kv4 channels...
    21 KB (2,413 words) - 04:36, 22 June 2024
  • Thumbnail for KCND3
    KCND3 (redirect from Kv4.3)
    Potassium voltage-gated channel subfamily D member 3 also known as Kv4.3 is a protein that in humans is encoded by the KCND3 gene. It contributes to the...
    9 KB (1,208 words) - 20:33, 3 March 2023
  • Thumbnail for KCND2
    KCND2 (redirect from Kv4.2)
    Schwarz M, Isbrandt D, Pongs O (December 1999). "Characterization of human Kv4.2 mediating a rapidly-inactivating transient voltage-sensitive K+ current"...
    12 KB (1,213 words) - 05:24, 25 October 2023
  • October 2014. Retrieved 24 October 2014. The National Archives, Kew, file no. KV4/227 p. 9. "Document". Document. London. 14 July 2015. BBC. BBC Radio 4. Retrieved...
    14 KB (1,638 words) - 00:36, 3 August 2024
  • Thumbnail for KCND1
    KCND1 (redirect from Kv4.1)
    voltage-gated channel, Shal-related subfamily, member 1 (KCND1), also known as Kv4.1, is a human gene. Voltage-gated potassium (Kv) channels represent the most...
    5 KB (587 words) - 00:13, 17 July 2024
  • Thumbnail for Heteropoda venatoria
    structure of hpTX2, a toxin from Heteropoda venatoria spider that blocks Kv4.2 potassium channel. Protein Science 9(11), 2059-67. "Spiders in Bermuda"...
    7 KB (673 words) - 08:59, 11 May 2024
  • Thumbnail for Autoimmune encephalitis
    lymphocytic leukemia. Dipeptidyl peptidase-like protein 6 (DPPX) is a subunit of Kv4.2 potassium channels expressed in the hippocampus, cerebellum, striatum,...
    34 KB (3,413 words) - 11:29, 24 June 2024
  • Thumbnail for Heteropodatoxin
    from the venom of the giant crab spider Heteropoda venatoria, which block Kv4.2 voltage-gated potassium channels. Heteropodatoxins are purified from the...
    4 KB (445 words) - 16:33, 19 July 2023
  • 25329 1999 JO84 — May 12, 1999 Socorro LINEAR  · 3.9 km MPC · JPL 25330 1999 KV4 — May 17, 1999 Catalina CSS APO +1km 3.2 km MPC · JPL 25331 Berrevoets 1999...
    190 KB (301 words) - 18:00, 30 November 2023
  • BmP02 (section Kv4.2)
    acts on potassium channels, blocking Kv1.3 and slowing the deactivation of Kv4.2. BmP02 is not toxic to humans or mice. The BmP02 toxin is a component of...
    10 KB (1,324 words) - 11:02, 15 May 2024
  • Thumbnail for Valley of the Kings
    the tombs, providing information and plans of the open tombs. KV1 KV2 KV3 KV4 KV5 KV6 KV7 KV8 KV9 KV10 KV11 KV12 KV13 KV14 KV15 KV16 KV17 KV18 KV19 KV20...
    64 KB (7,176 words) - 20:06, 7 August 2024
  • Thumbnail for KV5
    East Valley of the Kings Discovered 1825 Excavated by Kent R. Weeks (1995) Decoration Opening of the Mouth Layout Labyrinth ← Previous KV4 Next → KV6...
    5 KB (593 words) - 13:54, 25 May 2024
  • Thumbnail for Quinidine
    Quinidine also blocks certain voltage-gated potassium channels (e.g., Kv1.4, Kv4.2, hERG, among others), acts as an antimuscarinic and alpha-1 blocker, and...
    19 KB (1,862 words) - 01:53, 8 April 2024
  • Thumbnail for Ctri9577
    blocker of the voltage-gated potassium channel Kv1.3, and a gating modifier of Kv4.3 channels. The Ctri9577 toxin is a component of the venom of the scorpion...
    7 KB (728 words) - 03:58, 23 June 2024
  • serrulatus. Ts8 is a selective inhibitor of the voltage-gated potassium channel Kv4.2 The neurotoxin Ts8 can be derived from the venom from the Brazilian yellow...
    7 KB (908 words) - 20:41, 23 June 2024
  • Thumbnail for BrMT
    humans (hKv1.1) and squid (sqKv1.A). It also affects members of Kv4 family (Kv4.1 and Kv4.2) and Drosophila ether-à-go-go channels. The mode of action of...
    6 KB (598 words) - 08:56, 7 March 2024
  • Thumbnail for Cardiac action potential
    Phase / role Na+ INa NaV1.5 SCN5A 0 Ca2+ ICa(L) CaV1.2 CACNA1C 0-2 K+ Ito1 KV4.2/4.3 KCND2/KCND3 1, notch K+ IKs KV7.1 KCNQ1 2,3 K+ IKr KV11.1 (hERG) KCNH2...
    46 KB (5,430 words) - 18:10, 24 April 2024
  • venom of Androctonus australis. The toxin acts as a specific blocker on Kv4.3 voltage-gated potassium channel, thereby abolishing the A-type potassium...
    4 KB (434 words) - 06:28, 22 June 2020
  • Thumbnail for Heteroscodratoxin-1
    delayed rectifier (KV2.1 and KV2.2) and A-type rapidly inactivating (KV4.1, KV4.2 and KV4.3) voltage-gated potassium channels. At a concentration of 100-300...
    7 KB (850 words) - 18:42, 8 June 2023
  • Thumbnail for Phrixotoxin
    -2 are similar to heteropodatoxin, which also has a blocking activity on Kv4.2 channels (Chagot 2004) harv error: no target: CITEREFChagot2004 (help)...
    6 KB (692 words) - 20:04, 19 August 2021
  • to designate tombs located in the West Valley (of the Kings). KV1 KV2 KV3 KV4 KV5 KV6 KV7 KV8 KV9 KV10 KV11 KV12 KV13 KV14 KV15 KV16 KV17 KV18 KV19 KV20...
    23 KB (879 words) - 02:30, 25 June 2024
  • 54 nM). BmTx3 blocks primarily the Kv4.x proteins and has a higher affinity for Kv4.1 channels than for Kv4.2 and Kv4.3 channels. The second functional...
    6 KB (697 words) - 22:09, 30 January 2023
  • Thumbnail for Brugada syndrome
    calcium channel carrying the L-type calcium current ICa(L). BrS10 605411 KCND3 KV4.3, α-subunit of the transient outward potassium channel Ito. BrS11 607954...
    54 KB (5,883 words) - 17:35, 2 August 2024
  • Thumbnail for Meretseger
    Ramesses X (c. 1111–1107 BC), where she appears with Ra-Horakhty; the tomb (KV4) of Pharaoh Ramesses XI (c. 1107–1077 BC), where she appears with many deities...
    15 KB (1,771 words) - 10:10, 5 August 2024
  • until Cys29 and Arg33 until Cys36. Discrepin blocks voltage-gated Shal-type (Kv4.x) K+ channels in cerebellar granular cells. These A-type K+ channels regulate...
    4 KB (569 words) - 08:46, 25 May 2020
  • Thumbnail for List of Earth-crossing asteroids
    OG 18 (24445) 2000 PM8 † 19 24761 Ahau 20 25143 Itokawa 21 (25330) 1999 KV4 22 (26379) 1999 HZ1 23 (26663) 2000 XK47 24 (27002) 1998 DV9 † 25 (29075)...
    12 KB (1,450 words) - 13:30, 29 May 2024
  • Thumbnail for KCNIP1
    other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal...
    8 KB (871 words) - 22:45, 16 July 2024
  • Thumbnail for Voltage-gated potassium channel
    x - Shaker-related: Kv1.4 (KCNA4) Kvα4.x - Shal-related: Kv4.1 (KCND1), Kv4.2 (KCND2), Kv4.3 (KCND3) Kvα10.x: Kv10.2 (KCNH5) Passes current more easily...
    17 KB (1,769 words) - 15:18, 22 June 2024