KV4 is a tomb in the Valley of the Kings (Egypt). The tomb was initiated for the burial of Ramesses XI but it is likely that its construction was abandoned...
9 KB (1,162 words) - 18:16, 8 July 2023
toxin selectively inhibits Kv4.2 voltage-gated potassium channels by acting as a gating modifier. TLTx is part of the family of Kv4-specific tarantula toxins...
4 KB (530 words) - 02:26, 29 November 2023
Kv3 and Kv4. The Kv1 channel primarily influences the repolarization of the axon. The Kv2 channel is characteristically activated slower. The Kv4 channels...
21 KB (2,413 words) - 04:36, 22 June 2024
October 2014. Retrieved 24 October 2014. The National Archives, Kew, file no. KV4/227 p. 9. "Document". Document. London. 14 July 2015. BBC. BBC Radio 4. Retrieved...
14 KB (1,638 words) - 00:36, 3 August 2024
structure of hpTX2, a toxin from Heteropoda venatoria spider that blocks Kv4.2 potassium channel. Protein Science 9(11), 2059-67. "Spiders in Bermuda"...
7 KB (673 words) - 08:59, 11 May 2024
lymphocytic leukemia. Dipeptidyl peptidase-like protein 6 (DPPX) is a subunit of Kv4.2 potassium channels expressed in the hippocampus, cerebellum, striatum,...
34 KB (3,413 words) - 11:29, 24 June 2024
from the venom of the giant crab spider Heteropoda venatoria, which block Kv4.2 voltage-gated potassium channels. Heteropodatoxins are purified from the...
4 KB (445 words) - 16:33, 19 July 2023
List of minor planets: 25001–26000 (redirect from (25330) 1999 KV4)
25329 1999 JO84 — May 12, 1999 Socorro LINEAR · 3.9 km MPC · JPL 25330 1999 KV4 — May 17, 1999 Catalina CSS APO +1km 3.2 km MPC · JPL 25331 Berrevoets 1999...
190 KB (301 words) - 18:00, 30 November 2023
the tombs, providing information and plans of the open tombs. KV1 KV2 KV3 KV4 KV5 KV6 KV7 KV8 KV9 KV10 KV11 KV12 KV13 KV14 KV15 KV16 KV17 KV18 KV19 KV20...
64 KB (7,176 words) - 20:06, 7 August 2024
East Valley of the Kings Discovered 1825 Excavated by Kent R. Weeks (1995) Decoration Opening of the Mouth Layout Labyrinth ← Previous KV4 Next → KV6...
5 KB (593 words) - 13:54, 25 May 2024
Quinidine also blocks certain voltage-gated potassium channels (e.g., Kv1.4, Kv4.2, hERG, among others), acts as an antimuscarinic and alpha-1 blocker, and...
19 KB (1,862 words) - 01:53, 8 April 2024
blocker of the voltage-gated potassium channel Kv1.3, and a gating modifier of Kv4.3 channels. The Ctri9577 toxin is a component of the venom of the scorpion...
7 KB (728 words) - 03:58, 23 June 2024
serrulatus. Ts8 is a selective inhibitor of the voltage-gated potassium channel Kv4.2 The neurotoxin Ts8 can be derived from the venom from the Brazilian yellow...
7 KB (908 words) - 20:41, 23 June 2024
humans (hKv1.1) and squid (sqKv1.A). It also affects members of Kv4 family (Kv4.1 and Kv4.2) and Drosophila ether-à-go-go channels. The mode of action of...
6 KB (598 words) - 08:56, 7 March 2024
Phase / role Na+ INa NaV1.5 SCN5A 0 Ca2+ ICa(L) CaV1.2 CACNA1C 0-2 K+ Ito1 KV4.2/4.3 KCND2/KCND3 1, notch K+ IKs KV7.1 KCNQ1 2,3 K+ IKr KV11.1 (hERG) KCNH2...
46 KB (5,430 words) - 18:10, 24 April 2024
venom of Androctonus australis. The toxin acts as a specific blocker on Kv4.3 voltage-gated potassium channel, thereby abolishing the A-type potassium...
4 KB (434 words) - 06:28, 22 June 2020
delayed rectifier (KV2.1 and KV2.2) and A-type rapidly inactivating (KV4.1, KV4.2 and KV4.3) voltage-gated potassium channels. At a concentration of 100-300...
7 KB (850 words) - 18:42, 8 June 2023
-2 are similar to heteropodatoxin, which also has a blocking activity on Kv4.2 channels (Chagot 2004) harv error: no target: CITEREFChagot2004 (help)...
6 KB (692 words) - 20:04, 19 August 2021
to designate tombs located in the West Valley (of the Kings). KV1 KV2 KV3 KV4 KV5 KV6 KV7 KV8 KV9 KV10 KV11 KV12 KV13 KV14 KV15 KV16 KV17 KV18 KV19 KV20...
23 KB (879 words) - 02:30, 25 June 2024
54 nM). BmTx3 blocks primarily the Kv4.x proteins and has a higher affinity for Kv4.1 channels than for Kv4.2 and Kv4.3 channels. The second functional...
6 KB (697 words) - 22:09, 30 January 2023
calcium channel carrying the L-type calcium current ICa(L). BrS10 605411 KCND3 KV4.3, α-subunit of the transient outward potassium channel Ito. BrS11 607954...
54 KB (5,883 words) - 17:35, 2 August 2024
Ramesses X (c. 1111–1107 BC), where she appears with Ra-Horakhty; the tomb (KV4) of Pharaoh Ramesses XI (c. 1107–1077 BC), where she appears with many deities...
15 KB (1,771 words) - 10:10, 5 August 2024
until Cys29 and Arg33 until Cys36. Discrepin blocks voltage-gated Shal-type (Kv4.x) K+ channels in cerebellar granular cells. These A-type K+ channels regulate...
4 KB (569 words) - 08:46, 25 May 2020
OG 18 (24445) 2000 PM8 † 19 24761 Ahau 20 25143 Itokawa 21 (25330) 1999 KV4 22 (26379) 1999 HZ1 23 (26663) 2000 XK47 24 (27002) 1998 DV9 † 25 (29075)...
12 KB (1,450 words) - 13:30, 29 May 2024
other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal...
8 KB (871 words) - 22:45, 16 July 2024
x - Shaker-related: Kv1.4 (KCNA4) Kvα4.x - Shal-related: Kv4.1 (KCND1), Kv4.2 (KCND2), Kv4.3 (KCND3) Kvα10.x: Kv10.2 (KCNH5) Passes current more easily...
17 KB (1,769 words) - 15:18, 22 June 2024