encoded by the KNG1 gene. Kininogen-1 is the precursor protein to high-molecular-weight kininogen (HMWK), low-molecular-weight kininogen (LMWK), and bradykinin...

two main types of kininogen (KNG), high-molecular-weight-kininogen and low-molecular-weight-kininogen, with a third type – T-kininogen – only found in rats...

High-molecular-weight kininogen (HMWK or HK) is a circulating plasma protein which participates in the initiation of blood coagulation, and in the generation...

associated with mutations in genes for Factor XII, angiopoietin 1, plasminogen or kininogen 1. The pathophysiologic mechanisms contributing to bradykinin...

Low-molecular-weight kininogen is a form of kininogen, which has been identified in mice, guinea pigs, and whales. It is also found in humans. Shesely...

makes bradykinin by proteolytic cleavage of its kininogen precursor, high-molecular-weight kininogen (HMWK or HK), by the enzyme kallikrein. Moreover...

plasma contact system by binding to factor XII and high molecular weight kininogen". Journal of Biological Chemistry. 277 (31): 27651–8. doi:10.1074/jbc...

compounds.[citation needed] High-molecular weight kininogen (HMWK) and low-molecular weight kininogen (LMWK) are precursors of the polypeptides. They have...

subsequent proteolysis of kininogen. The proteolysis of the kininogen forces an upscaled production of bradykinin and kininogen within the patient. Increased...

defibrinating action results in anticoagulant blood, the venom also has a kininogen-like action; it causes the body to release substances such as bradykinin...

subdivided as described below. Cystatins show similarity to fetuins, kininogens, histidine-rich glycoproteins and cystatin-related proteins. Cystatins...

of some Arg- and Lys- bonds, including Lys-Arg and Arg-Ser in (human) kininogen to release bradykinin Plasma kallikrein and its precursor are encoded...

an 85,000 Mr serine protease that complexes with high-molecular-weight kininogen. PK is the precursor of plasma kallikrein, which is a serine protease...

Kallikrein, an enzyme that proteolytically cleaves high-molecular-weight kininogen to produce bradykinin, which is a vasodilator; it is secreted by the acinar...

formation of the primary complex on collagen by high-molecular-weight kininogen (HMWK), prekallikrein, and FXII (Hageman factor). Prekallikrein is converted...

members of the autacoid family. Kinins are peptides that are cleaved from kininogens by the process of kallikreins. Kallikreins activate kinins when stimulated...

kallikrein, which liberates the kinins bradykinin and kallidin from their kininogen precursors and is produced in excess in individuals with HAE types I and...

peptide, Lys-bradykinin, from low molecular weight kininogen. Kinin–kallikrein system Kininogen 1 GRCh38: Ensembl release 89: ENSG00000167748 – Ensembl...

bradykinin from high- and low-molecular-weight kininogen. Plasmin has been shown to interact with Thrombospondin 1, Alpha 2-antiplasmin and IGFBP3. Moreover...

within this superfamily are the histidine-rich glycoprotein (HRG) and kininogen (KNG). The function of Fetuin-A in the body was determined by gene knockout...

on a biopolymer surface and is later replaced by high molecular weight kininogen. The process is delayed in narrow spaces and on hydrophobic surfaces,...

contains a binding site for thrombin, another for high molecular weight kininogen, a third one for factor IX, heparin and glycoprotein Ib and the fourth...

families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine...

1992). "Bioregulation of kinins: kallikreins, kininogens, and kininases". Pharmacological Reviews. 44 (1): 1–80. PMID 1313585. Offermanns S, Rosenthal W...

blood, factor XII (FXII), prekallikrein (PK) and high molecular weight kininogen (HK), bind to a surface and cause blood coagulation and inflammation....

1992). "Bioregulation of kinins: kallikreins, kininogens, and kininases". Pharmacological Reviews. 44 (1): 1–80. PMID 1313585. Stefan Offermanns; Walter...

Kallidin is a bioactive kinin formed in response to injury from kininogen precursors through the action of kallikreins. Kallidin is a decapeptide whose...

dysplasia type Christianson Fouris High scapula High-molecular-weight kininogen deficiency, congenital Hillig syndrome Hing–Torack–Dowston syndrome Hinson–Pepys...

contact factors, prekallikrein (Fletcher factor) and high molecular weight kininogen. Excess levels of factor XII can predispose individuals towards greater...

as thrombin, P-selectin, factor XI, factor XII, high molecular weight kininogen as well as bacteria. GPIb-IX-V offers a critical role in thrombosis, metastasis...