• Thumbnail for Leucine zipper
    A leucine zipper (or leucine scissors) is a common three-dimensional structural motif in proteins. They were first described by Landschulz and collaborators...
    16 KB (2,049 words) - 22:57, 18 September 2024
  • Thumbnail for Leucine
    photochemical origin of biomolecules' homochirality. Leucines, the isomers and derivatives of leucine Leucine zipper, a common motif in transcription factor proteins...
    27 KB (4,132 words) - 00:11, 7 September 2024
  • Thumbnail for NRL (gene)
    retina-specific leucine zipper protein is a protein that in humans is encoded by the NRL gene. This gene encodes a basic motif-leucine zipper transcription...
    9 KB (1,095 words) - 14:20, 24 December 2023
  • Thumbnail for Alpha helix
    for leucine zipper for such a diagram). Often in globular proteins, as well as in specialized structures such as coiled-coils and leucine zippers, an...
    46 KB (5,219 words) - 01:46, 14 August 2024
  • Thumbnail for SNARE protein
    it is flanked by leucine zippering. Layers '-1', '+1' and '+2' at the centre of the complex most closely follow ideal leucine-zipper geometry and aminoacid...
    53 KB (6,592 words) - 12:55, 13 October 2024
  • Thumbnail for AP-1 transcription factor
    region leucine zipper) in the Fos and Jun subunits. A typical bZIP domain consists of a “leucine zipper” region, and a “basic region”. The leucine zipper is...
    41 KB (4,468 words) - 17:08, 21 September 2024
  • helix with a leucine at every 7th amino acid. If two such helices find one another, the leucines can interact as the teeth in a zipper, allowing dimerization...
    19 KB (2,167 words) - 16:54, 24 September 2024
  • aggregate in solution. Chimeras of these HR1-derived peptides with GCN4 leucine zippers have been developed and have shown to be more active than Fuzeon. The...
    34 KB (3,860 words) - 13:37, 5 October 2024
  • Thumbnail for MELK
    Maternal embryonic leucine zipper kinase (MELK) is an enzyme that in humans is encoded by the MELK gene. MELK is a serine/threonine kinase belonging to...
    8 KB (977 words) - 02:25, 3 December 2023
  • Thumbnail for BZIP domain
    The Basic Leucine Zipper Domain (bZIP domain) is found in many DNA binding eukaryotic proteins. One part of the domain contains a region that mediates...
    7 KB (663 words) - 00:42, 13 March 2024
  • helix-loop-helix leucine zipper transcription factors are, as their name indicates, transcription factors containing both Basic helix-loop-helix and leucine zipper motifs...
    584 bytes (61 words) - 15:38, 16 April 2020
  • Thumbnail for Basic leucine zipper and W2 domain-containing protein 2
    Basic Leucine Zipper and W2 Domain-Containing Protein 2 is a protein that is encoded by the BZW2 gene. It is a eukaryotic translation factor[vague] found...
    17 KB (1,647 words) - 17:10, 3 May 2024
  • Thumbnail for Leucine-rich repeat
    appear to have reversible redox activity. Leucine zipper Kobe B, Deisenhofer J (October 1994). "The leucine-rich repeat: a versatile binding motif". Trends...
    11 KB (1,070 words) - 16:42, 9 September 2024
  • Thumbnail for NFE2L2
    factor that in humans is encoded by the NFE2L2 gene. NRF2 is a basic leucine zipper (bZIP) protein that may regulate the expression of antioxidant proteins...
    29 KB (3,402 words) - 07:08, 20 May 2024
  • Thumbnail for BATF (gene)
    Basic leucine zipper transcription factor, ATF-like, also known as BATF, is a protein which in humans is encoded by the BATF gene. The protein encoded...
    7 KB (885 words) - 04:32, 3 January 2024
  • Thumbnail for Heat shock factor protein 1
    two regions responsible for oligomerization between HSF1 monomers are leucine zipper (LZ) domains 1-3 and 4 (these regions are also commonly referred to...
    20 KB (2,454 words) - 08:11, 2 November 2024
  • mature protein is 6 kDa in size. Three monomers of Lpp assemble into a leucine zipper coiled-coil trimer. Large amounts of Braun's lipoprotein is present...
    5 KB (572 words) - 15:03, 1 October 2024
  • Thumbnail for BLZF1
    Berger R, Chen Z, Lanotte M (May 1997). "JEM-1, a novel gene encoding a leucine-zipper nuclear factor upregulated during retinoid-induced maturation of NB4...
    4 KB (567 words) - 04:51, 14 March 2022
  • Thumbnail for LZTR1
    Leucine-zipper-like transcriptional regulator 1 is a protein that in humans is encoded by the LZTR1 gene. The LZTR1 gene provides instructions for making...
    9 KB (1,252 words) - 16:33, 22 November 2023
  • components of the MAPK cascade and is homologous to glucocorticoid-induced leucine zipper (GILZ). GILZ can be induced by Dexamethasone. It prevents Raf-1 activation...
    24 KB (2,895 words) - 11:08, 9 September 2024
  • Thumbnail for ASZ1
    Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 is a protein that in humans is encoded by the ASZ1 gene. GRCh38: Ensembl release...
    3 KB (386 words) - 00:08, 29 January 2023
  • Thumbnail for CREB
    of another CREB protein forming a dimer. This chain of leucine residues forms the leucine zipper motif. The protein also has a magnesium ion that facilitates...
    19 KB (2,243 words) - 23:46, 9 September 2024
  • Thumbnail for CCAAT-enhancer-binding proteins
    gene promoters. They are characterized by a highly conserved basic-leucine zipper (bZIP) domain at the C-terminus. This domain is involved in dimerization...
    15 KB (1,802 words) - 05:16, 25 July 2024
  • Thumbnail for Herpes simplex virus
    of portal protein, UL6, arranged as a ring; the proteins contain a leucine zipper sequence of amino acids, which allow them to adhere to each other. Each...
    68 KB (7,356 words) - 01:20, 2 November 2024
  • helix-loop-helix) and LZ (leucine zipper) structural motifs. The bHLH motif allows Myc proteins to bind with DNA, while the leucine zipper TF-binding motif allows...
    57 KB (6,672 words) - 01:42, 9 October 2024
  • Thumbnail for LDOC1L
    Leucine zipper, down-regulated in cancer 1 like is a protein that in humans is encoded by the LDOC1L gene. GRCh38: Ensembl release 89: ENSG00000188636...
    527 bytes (81 words) - 11:39, 4 March 2023
  • Thumbnail for Transcription factor
    rodents and also to plants. 1 Superclass: Basic Domains 1.1 Class: Leucine zipper factors (bZIP) 1.1.1 Family: AP-1(-like) components; includes (c-Fos/c-Jun)...
    74 KB (8,186 words) - 07:58, 28 October 2024
  • Werkgeversvereniging, Brabant-Zealandic Employers association Any of two basic leucine zipper and W2 domain-containing proteins (BZW): BZW1 BZW2 .bzw, file extension...
    603 bytes (101 words) - 20:31, 10 April 2024
  • Thumbnail for ATF4
    (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein–protein interactions, located C-terminal...
    15 KB (1,773 words) - 00:39, 27 September 2024
  • Thumbnail for TSC22D3
    identity with the murine TSC-22 and Drosophila shs, both of which are leucine zipper proteins, that function as transcriptional regulators. GILZ shows ubiquitous...
    9 KB (1,186 words) - 11:54, 3 December 2023