Leukemia inhibitory factor, or LIF, is an interleukin 6 class cytokine that affects cell growth by inhibiting differentiation. When LIF levels drop, the...
13 KB (1,585 words) - 05:48, 10 March 2024
Differentiation 118), is a subunit of a receptor for leukemia inhibitory factor. The leukemia inhibitory factor (LIF) is a polyfunctional cytokine that affects...
11 KB (1,325 words) - 16:37, 6 April 2024
Implantation (embryology) (section Other factors)
there is no evidence to support their involvement in hatching. Leukemia inhibitory factor (LIF) is a pro-inflammatory cytokine expressed in the endometrium...
51 KB (5,851 words) - 05:16, 2 May 2024
group of cytokines. Of these cytokines it most closely resembles leukemia inhibitory factor (LIF) in both structure and function. As yet poorly defined, it...
32 KB (4,317 words) - 13:05, 12 April 2024
motility factor Bone morphogenetic proteins (BMPs) Ciliary neurotrophic factor family Ciliary neurotrophic factor (CNTF) Leukemia inhibitory factor (LIF)...
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unknown. The CNTF family of neurotrophic factors includes ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), interleukin-6 (IL-6), prolactin...
16 KB (1,784 words) - 04:08, 6 January 2024
with gp130, such as cardiotrophin 1 (CT-1), leukemia inhibitory factor (LIF), ciliary neurotrophic factor (CNTF), oncostatin M (OSM), and IL-11. There...
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growth factors and is frequently added to growth media used for eukaryotic cell culture. A combination of FBS and the cytokine leukemia inhibitory factor was...
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negative regulating factors are known (such as dopamine, leukemia inhibitory factor, some prostaglandins) but few stimulating factor. Its secretion is mediated...
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RANKL (redirect from Osteoclast differentiation factor)
Receptor activator of nuclear factor kappa-Β ligand (RANKL), also known as tumor necrosis factor ligand superfamily member 11 (TNFSF11), TNF-related activation-induced...
28 KB (3,372 words) - 21:06, 8 March 2024
F, et al. (2003). "Vascular endothelial growth factor and its receptors in multiple myeloma". Leukemia. 17 (10): 1961–6. doi:10.1038/sj.leu.2403076. PMID 14513045...
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example, they have substantially improved outcomes in chronic myelogenous leukemia. They have also been used to treat other diseases, such as idiopathic pulmonary...
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Heinrich PC, Schaper F (2000). "Signal transduction of IL-6, leukemia-inhibitory factor, and oncostatin M: structural receptor requirements for signal...
16 KB (1,922 words) - 21:02, 8 November 2023
album A Natural Death "Líf", a song by Hildur Vala Einarsdóttir Leukemia inhibitory factor, a cytokine that affects cell growth and development Laser-induced...
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Brain-derived neurotrophic factor (BDNF), or abrineurin, is a protein that, in humans, is encoded by the BDNF gene. BDNF is a member of the neurotrophin...
45 KB (5,341 words) - 08:28, 10 June 2024
Tyrosine kinase (section Chronic myeloid leukemia)
growth factor receptor (EGFR) mutation BCR-ABL is a constitutively activated tyrosine kinase that is associated with chronic myeloid leukemia. It is formed...
43 KB (5,251 words) - 10:44, 24 June 2024
Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the regulation of growth, maintenance, proliferation, and survival...
23 KB (2,756 words) - 04:47, 10 July 2024
Shew JY, Ho HN, Hsu WL, Yang YS (October 1999). "Expression of leukemia inhibitory factor and its receptor in preimplantation embryos". Fertil. Steril....
34 KB (3,875 words) - 23:00, 9 June 2024
lab with media containing serum and leukemia inhibitory factor or serum-free media supplements with two inhibitory drugs ("2i"), the MEK inhibitor PD03259010...
73 KB (8,680 words) - 00:23, 26 April 2024
neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), nerve growth factor (NGF), and ciliary neurotrophic factor (CNTF). Although...
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Coupey L, et al. (1996). "Binding interactions of leukemia inhibitory factor and ciliary neurotrophic factor with the different subunits of their high affinity...
15 KB (1,740 words) - 14:38, 3 December 2023
Fibroblast growth factor 2, also known as basic fibroblast growth factor (bFGF) and FGF-β, is a growth factor and signaling protein encoded by the FGF2...
22 KB (2,693 words) - 04:46, 19 April 2024
Interleukin 6 (category Neurotrophic factors)
signal transducer for several cytokines including leukemia inhibitory factor (LIF), ciliary neurotropic factor, oncostatin M, IL-11 and cardiotrophin-1, and...
63 KB (7,455 words) - 14:38, 9 July 2024
eosinophilic leukemia; b) a form of myeloproliferative neoplasm/myeloblastic leukemia associated with little or no eosinophilia; c) T-lymphoblastic leukemia/lymphoma...
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are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones. Of the 90 unique tyrosine kinase genes identified...
28 KB (3,078 words) - 07:46, 3 June 2024
of acidic amino acids located between the D1 and D2 domains has auto-inhibitory functions. This 'acid box' motif interacts with the heparan sulfate binding...
25 KB (3,123 words) - 20:10, 26 April 2024
Imatinib (section Chronic myelogenous leukemia)
acute lymphoblastic leukemia (Ph+ ALL), myelodysplastic/myeloproliferative diseases associated with platelet-derived growth factor receptor gene rearrangements...
71 KB (6,661 words) - 22:48, 2 July 2024
between them. The relative potency of these effects can depend on various factors and is a topic of ongoing research. Testosterone can either directly exert...
150 KB (15,741 words) - 10:52, 27 June 2024
carcinomas with specific mutations. It is a third-generation epidermal growth factor receptor tyrosine kinase inhibitor. The most common side effects include...
17 KB (1,489 words) - 05:47, 7 April 2024
growth factor 21 is a protein that in mammals is encoded by the FGF21 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF)...
24 KB (3,036 words) - 16:02, 18 May 2024