• Thumbnail for Leukemia inhibitory factor
    Leukemia inhibitory factor, or LIF, is an interleukin 6 class cytokine that affects cell growth by inhibiting differentiation. When LIF levels drop, the...
    13 KB (1,585 words) - 05:48, 10 March 2024
  • Thumbnail for Leukemia inhibitory factor receptor
    Differentiation 118), is a subunit of a receptor for leukemia inhibitory factor. The leukemia inhibitory factor (LIF) is a polyfunctional cytokine that affects...
    11 KB (1,325 words) - 16:37, 6 April 2024
  • Thumbnail for Implantation (embryology)
    there is no evidence to support their involvement in hatching. Leukemia inhibitory factor (LIF) is a pro-inflammatory cytokine expressed in the endometrium...
    51 KB (5,851 words) - 05:16, 2 May 2024
  • Thumbnail for Oncostatin M
    group of cytokines. Of these cytokines it most closely resembles leukemia inhibitory factor (LIF) in both structure and function. As yet poorly defined, it...
    32 KB (4,317 words) - 13:05, 12 April 2024
  • motility factor Bone morphogenetic proteins (BMPs) Ciliary neurotrophic factor family Ciliary neurotrophic factor (CNTF) Leukemia inhibitory factor (LIF)...
    10 KB (1,131 words) - 19:14, 31 March 2024
  • unknown. The CNTF family of neurotrophic factors includes ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), interleukin-6 (IL-6), prolactin...
    16 KB (1,784 words) - 04:08, 6 January 2024
  • Thumbnail for Glycoprotein 130
    with gp130, such as cardiotrophin 1 (CT-1), leukemia inhibitory factor (LIF), ciliary neurotrophic factor (CNTF), oncostatin M (OSM), and IL-11. There...
    18 KB (2,202 words) - 01:16, 14 June 2024
  • Thumbnail for Serum (blood)
    growth factors and is frequently added to growth media used for eukaryotic cell culture. A combination of FBS and the cytokine leukemia inhibitory factor was...
    7 KB (736 words) - 02:25, 11 July 2024
  • negative regulating factors are known (such as dopamine, leukemia inhibitory factor, some prostaglandins) but few stimulating factor. Its secretion is mediated...
    1 KB (181 words) - 14:07, 14 November 2022
  • Thumbnail for RANKL
    Receptor activator of nuclear factor kappa-Β ligand (RANKL), also known as tumor necrosis factor ligand superfamily member 11 (TNFSF11), TNF-related activation-induced...
    28 KB (3,372 words) - 21:06, 8 March 2024
  • F, et al. (2003). "Vascular endothelial growth factor and its receptors in multiple myeloma". Leukemia. 17 (10): 1961–6. doi:10.1038/sj.leu.2403076. PMID 14513045...
    40 KB (4,580 words) - 05:24, 3 June 2024
  • Thumbnail for Tyrosine kinase inhibitor
    example, they have substantially improved outcomes in chronic myelogenous leukemia. They have also been used to treat other diseases, such as idiopathic pulmonary...
    9 KB (1,081 words) - 04:46, 16 June 2022
  • Thumbnail for SOCS3
    Heinrich PC, Schaper F (2000). "Signal transduction of IL-6, leukemia-inhibitory factor, and oncostatin M: structural receptor requirements for signal...
    16 KB (1,922 words) - 21:02, 8 November 2023
  • album A Natural Death "Líf", a song by Hildur Vala Einarsdóttir Leukemia inhibitory factor, a cytokine that affects cell growth and development Laser-induced...
    1 KB (189 words) - 22:31, 11 May 2024
  • Thumbnail for Brain-derived neurotrophic factor
    Brain-derived neurotrophic factor (BDNF), or abrineurin, is a protein that, in humans, is encoded by the BDNF gene. BDNF is a member of the neurotrophin...
    45 KB (5,341 words) - 08:28, 10 June 2024
  • Thumbnail for Tyrosine kinase
    growth factor receptor (EGFR) mutation BCR-ABL is a constitutively activated tyrosine kinase that is associated with chronic myeloid leukemia. It is formed...
    43 KB (5,251 words) - 10:44, 24 June 2024
  • Thumbnail for Nerve growth factor
    Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the regulation of growth, maintenance, proliferation, and survival...
    23 KB (2,756 words) - 04:47, 10 July 2024
  • Thumbnail for Cytokine
    Shew JY, Ho HN, Hsu WL, Yang YS (October 1999). "Expression of leukemia inhibitory factor and its receptor in preimplantation embryos". Fertil. Steril....
    34 KB (3,875 words) - 23:00, 9 June 2024
  • Thumbnail for Embryonic stem cell
    lab with media containing serum and leukemia inhibitory factor or serum-free media supplements with two inhibitory drugs ("2i"), the MEK inhibitor PD03259010...
    73 KB (8,680 words) - 00:23, 26 April 2024
  • neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), nerve growth factor (NGF), and ciliary neurotrophic factor (CNTF). Although...
    13 KB (1,177 words) - 18:50, 10 July 2024
  • Thumbnail for Ciliary neurotrophic factor
    Coupey L, et al. (1996). "Binding interactions of leukemia inhibitory factor and ciliary neurotrophic factor with the different subunits of their high affinity...
    15 KB (1,740 words) - 14:38, 3 December 2023
  • Thumbnail for Basic fibroblast growth factor
    Fibroblast growth factor 2, also known as basic fibroblast growth factor (bFGF) and FGF-β, is a growth factor and signaling protein encoded by the FGF2...
    22 KB (2,693 words) - 04:46, 19 April 2024
  • Thumbnail for Interleukin 6
    Interleukin 6 (category Neurotrophic factors)
    signal transducer for several cytokines including leukemia inhibitory factor (LIF), ciliary neurotropic factor, oncostatin M, IL-11 and cardiotrophin-1, and...
    63 KB (7,455 words) - 14:38, 9 July 2024
  • Thumbnail for Platelet-derived growth factor receptor A
    eosinophilic leukemia; b) a form of myeloproliferative neoplasm/myeloblastic leukemia associated with little or no eosinophilia; c) T-lymphoblastic leukemia/lymphoma...
    29 KB (3,354 words) - 17:01, 9 December 2023
  • Thumbnail for Receptor tyrosine kinase
    are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones. Of the 90 unique tyrosine kinase genes identified...
    28 KB (3,078 words) - 07:46, 3 June 2024
  • of acidic amino acids located between the D1 and D2 domains has auto-inhibitory functions. This 'acid box' motif interacts with the heparan sulfate binding...
    25 KB (3,123 words) - 20:10, 26 April 2024
  • Thumbnail for Imatinib
    acute lymphoblastic leukemia (Ph+ ALL), myelodysplastic/myeloproliferative diseases associated with platelet-derived growth factor receptor gene rearrangements...
    71 KB (6,661 words) - 22:48, 2 July 2024
  • Thumbnail for Testosterone
    between them. The relative potency of these effects can depend on various factors and is a topic of ongoing research. Testosterone can either directly exert...
    150 KB (15,741 words) - 10:52, 27 June 2024
  • Thumbnail for Osimertinib
    carcinomas with specific mutations. It is a third-generation epidermal growth factor receptor tyrosine kinase inhibitor. The most common side effects include...
    17 KB (1,489 words) - 05:47, 7 April 2024
  • Thumbnail for Fibroblast growth factor 21
    growth factor 21 is a protein that in mammals is encoded by the FGF21 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF)...
    24 KB (3,036 words) - 16:02, 18 May 2024