• Thumbnail for Locus coeruleus
    The locus coeruleus (/sɪˈruːliəs/) (LC), also spelled locus caeruleus or locus ceruleus, is a nucleus in the pons of the brainstem involved with physiological...
    38 KB (4,387 words) - 07:08, 13 May 2024
  • Thumbnail for Norepinephrine
    effects on other brain areas. The most important of these nuclei is the locus coeruleus, located in the pons. Outside the brain, norepinephrine is used as...
    59 KB (6,525 words) - 20:54, 14 August 2024
  • Thumbnail for Pre-locus coeruleus
    Pre-locus coeruleus is a small nucleus in the brainstem. This small cluster of neurons also is referred to by the abbreviation "pre-LC". It was named...
    9 KB (1,025 words) - 17:45, 10 January 2022
  • Thumbnail for Causes of autism
    developmental dysregulation that results in impaired function of the locus coeruleus–noradrenergic (LC-NA) system. The LC-NA system is heavily involved...
    145 KB (15,733 words) - 23:52, 11 July 2024
  • Thumbnail for Reticular formation
    these afferents to the cortex and therefore regulated wakefulness. Locus coeruleus Pedunculopontine nucleus Medial pontine reticular formation Midbrain...
    56 KB (5,506 words) - 06:47, 28 July 2024
  • Thumbnail for Neuromodulation
    noradrenaline system consists of around 15,000 neurons, primarily in the locus coeruleus. This is diminutive compared to the more than 100 billion neurons in...
    33 KB (3,070 words) - 04:59, 28 July 2024
  • Thumbnail for Rett syndrome
    hypothesize that the locus coeruleus is a critical site at which loss of MECP2 results in CNS dysfunction." The restoration of normal locus coeruleus function may...
    57 KB (6,112 words) - 22:09, 15 August 2024
  • Thumbnail for Neuromelanin
    catecholaminergic cells of the substantia nigra pars compacta and locus coeruleus, giving a dark color to the structures mostly found in Black or Brown...
    8 KB (853 words) - 19:25, 15 June 2024
  • Thumbnail for Adderall
    norepinephrine neurotransmission in the noradrenergic projections from the locus coeruleus to the prefrontal cortex. Psychostimulants like methylphenidate and...
    58 KB (21,539 words) - 12:58, 7 August 2024
  • withdrawal. Upregulation of the cAMP signal transduction pathway in the locus coeruleus by CREB has been implicated as the mechanism responsible for certain...
    56 KB (6,950 words) - 18:11, 14 August 2024
  • Thumbnail for Pupillary response
    load or demand. The responses correlate strongly with activity in the locus coeruleus neurotransmitter system. The pupils contract immediately before REM...
    11 KB (925 words) - 03:34, 19 August 2024
  • Thumbnail for Creativity
    on the locus coeruleus system. It describes how decision-making processes studied by neuroeconomists as well as activity in the locus coeruleus system...
    171 KB (19,567 words) - 06:49, 22 August 2024
  • Thumbnail for Arousal
    The noradrenergic system is a bundle of axons that originate in the locus coeruleus and ascends up into the neocortex, limbic system, and basal forebrain...
    49 KB (6,516 words) - 15:59, 26 July 2024
  • sympathetic activation. The nPGi is one of two major afferents of the locus coeruleus (LC), and sends collateral projections to the LC and to the nucleus...
    1 KB (124 words) - 18:05, 27 February 2022
  • Thumbnail for Parkinson's disease
    identified. Pathophysiology is characterized by nerve cell death in the locus coeruleus and substantia nigra, the latter being a midbrain region that supplies...
    169 KB (17,771 words) - 19:55, 23 August 2024
  • Thumbnail for Lisdexamfetamine
    norepinephrine neurotransmission in the noradrenergic projections from the locus coeruleus to the prefrontal cortex. Psychostimulants like methylphenidate and...
    45 KB (14,144 words) - 09:47, 21 August 2024
  • Thumbnail for Panic attack
    (labyrinthitis). Dysregulation of the norepinephrine system in the locus coeruleus, an area of the brain stem, has been linked to panic attacks. Panic...
    62 KB (6,424 words) - 09:33, 9 August 2024
  • Thumbnail for Dextroamphetamine
    norepinephrine neurotransmission in the noradrenergic projections from the locus coeruleus to the prefrontal cortex. Psychostimulants like methylphenidate and...
    59 KB (20,590 words) - 21:37, 17 August 2024
  • Thumbnail for Amphetamine
    norepinephrine neurotransmission in the noradrenergic projections from the locus coeruleus to the prefrontal cortex. Psychostimulants like methylphenidate and...
    274 KB (26,885 words) - 06:42, 26 August 2024
  • Thumbnail for Monoaminergic activity enhancer
    substantia nigra, and olfactory tubercle; norepinephrine release from the locus coeruleus; and/or serotonin release from the raphe nucleus in rodent studies...
    48 KB (5,097 words) - 15:53, 23 August 2024
  • Thumbnail for Serotonin–norepinephrine reuptake inhibitor
    brain. These regions are locus coeruleus and lateral tegmental. With administration of SNRIs, neuronal activity in locus coeruleus region is induced because...
    78 KB (7,687 words) - 09:12, 6 April 2024
  • Thumbnail for Rapid eye movement sleep
    originate in the brain stem, especially the pontine tegmentum and locus coeruleus. REM sleep is punctuated and immediately preceded by PGO (ponto-geniculo-occipital)...
    70 KB (8,445 words) - 18:35, 15 July 2024
  • divergent thinking. Convergent and divergent thinking depend on the locus coeruleus neurotransmission system, which modulates noradrenaline levels in the...
    19 KB (2,324 words) - 07:39, 26 August 2024
  • due to the stress of being born and the associated activation of the locus coeruleus. Dream argument Eugeroic High-conductance state Lucid dream Sleepwalking...
    7 KB (696 words) - 01:31, 29 December 2023
  • (CU Boulder). The Adaptive Behaviour Research Group (Sheffield). The locus coeruleus (LC) is one of the primary sources of noradrenaline in the brain, and...
    35 KB (4,135 words) - 15:43, 17 June 2024
  • Thumbnail for Hypothalamus
    brainstem, the most notable from the nucleus of the solitary tract, the locus coeruleus, and the ventrolateral medulla. Most nerve fibres within the hypothalamus...
    50 KB (4,969 words) - 01:43, 22 August 2024
  • Thumbnail for Unihemispheric slow-wave sleep
    commissure and increased decussation of ascending fibres from the locus coeruleus in the brainstem. This is consistent with the fact that one form for...
    25 KB (3,294 words) - 17:50, 28 May 2024
  • Thumbnail for Superior cerebellar peduncle
    fibers, tectocerebellar fibers, and noradrenergic fibers from the locus coeruleus. The superior peduncle emerges from the upper and medial parts of the...
    4 KB (465 words) - 13:37, 28 February 2021
  • Thumbnail for Oddball paradigm
    dilation that is produced by transient activity of the subcortical locus coeruleus. This pupil dilation effect is discussed to indicate a detection of...
    16 KB (1,929 words) - 02:39, 1 August 2024
  • The maintenance of fear has been shown to include the HPA axis, the locus coeruleus-noradrenergic systems, and the connections between the limbic system...
    204 KB (22,278 words) - 09:06, 25 August 2024