• Thumbnail for Low-affinity nerve growth factor receptor
    The p75 neurotrophin receptor (p75NTR) was first identified in 1973 as the low-affinity nerve growth factor receptor (LNGFR) before discovery that p75NTR...
    37 KB (4,235 words) - 21:48, 19 November 2024
  • Thumbnail for Nerve growth factor
    Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the regulation of growth, maintenance, proliferation, and survival...
    27 KB (3,061 words) - 16:55, 20 November 2024
  • Thumbnail for Brain-derived neurotrophic factor
    responding to this growth factor, TrkB (pronounced "Track B") and the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). It may...
    46 KB (5,344 words) - 17:28, 12 October 2024
  • Thumbnail for Cell surface receptor
    High affinity neurotrophin receptors Ephrin receptors Integrins Low Affinity Nerve Growth Factor Receptor NMDA receptor Several Immune receptors Toll-like...
    21 KB (2,456 words) - 22:14, 21 November 2023
  • Thumbnail for Tropomyosin receptor kinase A
    Tropomyosin receptor kinase A (TrkA), also known as high affinity nerve growth factor receptor, neurotrophic tyrosine kinase receptor type 1, or TRK1-transforming...
    28 KB (3,328 words) - 15:54, 29 October 2024
  • agonist of the tropomyosin receptor kinase A (TrkA) and low-affinity nerve growth factor receptor (p75NTR). The most common side effects include eye pain...
    7 KB (386 words) - 15:04, 6 November 2024
  • Thumbnail for Fibroblast growth factor receptor 2
    This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. FGFR2 has important...
    14 KB (1,745 words) - 09:02, 15 July 2024
  • Thumbnail for Hepatocyte growth factor receptor
    Hepatocyte growth factor receptor (HGF receptor) is a protein that in humans is encoded by the MET gene. The protein possesses tyrosine kinase activity...
    59 KB (6,727 words) - 06:01, 27 October 2024
  • Thumbnail for Epidermal growth factor
    Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. Human EGF is 6-kDa and has...
    17 KB (1,708 words) - 22:30, 15 October 2024
  • Thumbnail for Tropomyosin receptor kinase B
    Tropomyosin receptor kinase B (TrkB), also known as tyrosine receptor kinase B, or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type...
    39 KB (4,391 words) - 05:30, 23 October 2024
  • neurotrophic factor receptors are the p75 and the "Trk" families of Tyrosine kinases receptors. p75 is a low affinity neurotrophin receptor, to which all...
    5 KB (670 words) - 17:28, 23 January 2021
  • Thumbnail for Neurotrophin-3
    binds a second-receptor type besides Trk receptors, called the LNGFR (for "low affinity nerve growth factor receptor). TrkC is a receptor tyrosine kinase...
    14 KB (1,816 words) - 04:39, 31 October 2023
  • Thumbnail for Neurotrophin
    of receptors for neurotrophins: p75 and the "Trk" family of Tyrosine kinases receptors. Nerve growth factor (NGF), the prototypical growth factor, is...
    27 KB (3,078 words) - 19:34, 17 October 2024
  • Thumbnail for Tropomyosin receptor kinase C
    is one other NT-3 receptor family besides the Trks (TrkC & TrkB), called the "LNGFR" (for "low affinity nerve growth factor receptor"). As opposed to TrkC...
    32 KB (3,935 words) - 05:52, 22 September 2024
  • Thumbnail for Fibroblast growth factor receptor 3
    Fibroblast growth factor receptor 3 (FGFR-3) is a protein that in humans is encoded by the FGFR3 gene. FGFR3 has also been designated as CD333 (cluster...
    17 KB (1,845 words) - 01:41, 9 October 2024
  • Thumbnail for Placental growth factor
    Placental growth factor (PlGF) is a protein that in humans is encoded by the PGF gene. Placental growth factor (PGF) is a member of the VEGF (vascular...
    15 KB (1,923 words) - 18:07, 19 September 2024
  • Thumbnail for Somatostatin
    Pasireotide is somatostatin analog with a 40-fold increased affinity to somatostatin receptor 5 compared to other somatostatin analogs. Six somatostatin...
    23 KB (2,532 words) - 08:06, 21 July 2024
  • Vascular endothelial growth factor (VEGF, /vɛdʒˈɛf/), originally known as vascular permeability factor (VPF), is a signal protein produced by many cells...
    40 KB (4,578 words) - 12:30, 10 September 2024
  • Thumbnail for Olfactory ensheathing cell
    OECs have been identified with high or low cell surface expression of low-affinity nerve growth factor receptor (p75). Neuroscience Neuroglia Olfaction...
    18 KB (2,261 words) - 06:01, 3 June 2024
  • Thumbnail for TRAF2
    CD40, CFLAR, CHUK, Caveolin 1, EDARADD, HIVEP3, IKK2, Low affinity nerve growth factor receptor, MAP3K14, MAP3K1, MAP3K7IP2, MAP4K2, MAP4K5, RANK, RIPK1...
    29 KB (3,427 words) - 04:28, 25 December 2023
  • Thumbnail for George Yancopoulos
    receptor for BDNF, and showed that they were sufficient to mediate signaling without the requirement of the Low affinity Nerve Growth Factor receptor...
    28 KB (2,933 words) - 19:21, 20 November 2024
  • Thumbnail for NMDA receptor
    successful NMDA receptor antagonists for neurodegenerative diseases continued and focused on developing low affinity blockers. However the affinity could not...
    107 KB (12,058 words) - 11:59, 2 November 2024
  • Thumbnail for NGFRAP1
    gene. NGFRAP1 has been shown to interact with YWHAE and Low affinity nerve growth factor receptor. GRCh38: Ensembl release 89: ENSG00000166681 – Ensembl...
    6 KB (847 words) - 23:15, 4 September 2022
  • Thumbnail for Μ-opioid receptor
    The μ-opioid receptors (MOR) are a class of opioid receptors with a high affinity for enkephalins and beta-endorphin, but a low affinity for dynorphins...
    49 KB (4,880 words) - 05:38, 11 November 2024
  • Thumbnail for Prolactin
    cycle-related functions as a growth-, differentiating- and anti-apoptotic factor. As a growth factor, binding to cytokine-like receptors, it influences hematopoiesis...
    56 KB (5,820 words) - 00:14, 19 May 2024
  • inhibitory factor receptor Leukocyte extravasation Leukocyte-promoting factor Linear epitope Lipid A Lipopolysaccharide binding protein Low-affinity nerve growth...
    13 KB (1,237 words) - 01:24, 15 January 2024
  • Thumbnail for NDN (gene)
    has been shown to interact with: E2F1, HNRNPU, IL1A, Low affinity nerve growth factor receptor, NUCB2, and P53 ENSG00000288364 GRCh38: Ensembl release...
    11 KB (1,275 words) - 18:10, 27 December 2023
  • Thumbnail for Integrin
    Integrin (redirect from Integrin receptor)
    "beta1A integrin expression is required for type 1 insulin-like growth factor receptor mitogenic and transforming activities and localization to focal...
    36 KB (3,929 words) - 18:22, 21 September 2024
  • Thumbnail for Dehydroepiandrosterone
    Dehydroepiandrosterone (category GABAA receptor negative allosteric modulators)
    TrkA and p75NTR, receptors of neurotrophins like nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF), with high affinity. DHEA was subsequently...
    42 KB (3,937 words) - 11:44, 15 November 2024
  • Thumbnail for Alpha-2A adrenergic receptor
    PMID 2823383. Lynch CJ, Steer ML (April 1981). "Evidence for high and low affinity alpha 2-receptors. Comparison of [3H]norepinephrine and [3H]phentolamine binding...
    12 KB (1,303 words) - 04:16, 13 August 2024