Macrolides are a class of mostly natural products with a large macrocyclic lactone ring to which one or more deoxy sugars, usually cladinose and desosamine...
25 KB (2,811 words) - 04:16, 10 July 2024
Azithromycin (category Macrolide antibiotics)
confirmed, but it is likely safe. Azithromycin is an azalide, a type of macrolide antibiotic. It works by decreasing the production of protein, thereby...
59 KB (5,330 words) - 06:58, 20 June 2024
increasingly common. Resistance to multiple antibiotics, including the macrolide azithromycin, which until recently was the most reliable treatment, is...
45 KB (4,939 words) - 21:16, 22 July 2024
Erythromycin (category Macrolide antibiotics)
also applies if taken directly by the baby during this age. It is in the macrolide family of antibiotics and works by decreasing bacterial protein production...
41 KB (3,792 words) - 04:49, 22 June 2024
phenotype known as iMLSB. This phenotype of bacteria are resistant to the macrolide-lincosamide-streptogramin B group of antibiotics, however, the resistance...
44 KB (4,066 words) - 21:12, 8 June 2024
Clarithromycin (category Macrolide antibiotics)
been reported. It may cause harm if taken during pregnancy. It is in the macrolide class and works by slowing down bacterial protein synthesis. Clarithromycin...
27 KB (2,574 words) - 07:54, 1 July 2024
One important application are the many macrocyclic antibiotics, the macrolides, e.g. clarithromycin. Many metallocofactors are bound to macrocyclic ligands...
8 KB (794 words) - 05:30, 3 June 2024
In enzymology, a macrolide 2'-kinase (EC 2.7.1.136) is an enzyme that catalyzes the chemical reaction ATP + oleandomycin ⇌ {\displaystyle \rightleftharpoons...
1 KB (135 words) - 13:52, 11 January 2024
Rachel Fuller Brown and Elizabeth Lee Hazen. It was the first polyene macrolide antifungal. It is on the World Health Organization's List of Essential...
29 KB (2,600 words) - 12:47, 23 July 2024
either alone (mild to moderate severity disease) or in combination with a macrolide. The World Health Organization (WHO) recommends amoxicillin as first-line...
43 KB (3,825 words) - 03:13, 19 June 2024
but as an indicator it is not accurate enough to decide whether or not macrolide treatment should be used. The presence of chest pain in children with...
120 KB (12,708 words) - 18:58, 21 April 2024
clarithromycin, or azithromycin are typically the recommended treatment. Newer macrolides are frequently recommended due to lower rates of side effects....
48 KB (4,576 words) - 12:15, 13 July 2024
cephalosporins, monobactams (aztreonam), aminoglycosides, quinolones, macrolides, chloramphenicol, folate antagonists, and carbapenems. The adjectives...
24 KB (2,445 words) - 17:36, 19 July 2024
their tonsils. A drug-resistant strain of scarlet fever, resistant to macrolide antibiotics such as erythromycin, but retaining drug-sensitivity to beta-lactam...
62 KB (6,694 words) - 02:25, 27 July 2024
the genus Saccharopolyspora. Saccharopolyspora erythraea produces the macrolide antibiotic erythromycin. Cytochrome P450 eryF (CYP107A1) originally from...
3 KB (297 words) - 11:54, 13 May 2024
minimal relief provided for asthma symptoms. Macrolide antibiotics, particularly the azalide macrolide azithromycin, are a recently added Global Initiative...
167 KB (18,024 words) - 09:32, 22 July 2024
to macrolide treatment have been isolated and found to possess mutations at the transferase binding pocket in the 23S ribosomal subunit. Macrolide-resistant...
20 KB (2,133 words) - 12:14, 20 November 2023
recommended. In those who are allergic to penicillin, cephalosporins or macrolides may be used. In children with frequent episodes of tonsillitis, tonsillectomy...
33 KB (3,336 words) - 11:27, 27 May 2024
Ivermectin (category Macrolides)
Ivermectin is an antiparasitic drug. After its discovery in 1975, its first uses were in veterinary medicine to prevent and treat heartworm and acariasis...
79 KB (7,768 words) - 04:56, 3 July 2024
Ketolides are antibiotics belonging to the macrolide group. Ketolides are derived from erythromycin by substituting the cladinose sugar with a keto-group...
2 KB (314 words) - 07:19, 6 January 2024
such as certain anti-arrhythmics, anti-depressants, and quinolone or macrolide antibiotics. Another condition that promotes arrhythmias is Wolff-Parkinson-White...
125 KB (13,750 words) - 06:12, 27 July 2024
the overarching water safety plan. Effective antibiotics include most macrolides, tetracyclines, ketolides, and quinolones. Legionella spp. multiply within...
59 KB (5,883 words) - 03:20, 25 July 2024
Roxithromycin (category Macrolide antibiotics)
Roxithromycin is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. Roxithromycin is derived...
8 KB (428 words) - 13:57, 24 August 2023
Amino-penicillin Anti-pseudomonal BL−BLI Carbapenems Fluoro-quinolones Macrolide MDR & XDR Meticillin Mono INH Mono RIF Penicillin TMP-SMX Vancomycin Total...
42 KB (4,195 words) - 12:11, 8 May 2024
aspiration. Treatment may include more than one prescribed medication. Macrolides are often used to treat chancroid. The CDC recommendation is either a...
17 KB (1,735 words) - 10:52, 23 May 2024
Desosamine is a 3-(dimethylamino)-3,4,6-trideoxyhexose found in certain macrolide antibiotics (contain a high level of microbial resistance) such as the...
7 KB (670 words) - 18:56, 30 April 2023
especially to the commonly used tetracycline (e.g., doxycycline) and macrolide antibiotics (e.g., topical erythromycin). Therefore, dermatologists prefer...
167 KB (18,104 words) - 20:38, 26 June 2024
Azalide (category Macrolide antibiotics)
a class of macrolide antibiotics that were originally manufactured in response to the poor acid stability exhibited by original macrolides (erythromycin)...
4 KB (366 words) - 08:32, 16 February 2024
Tylosin (category Macrolide antibiotics)
Tylosin is a macrolide antibiotic and bacteriostatic feed additive used in veterinary medicine. It has a broad spectrum of activity against Gram-positive...
10 KB (798 words) - 00:49, 14 December 2023
membrane potential leading to inhibition of protein, DNA and RNA synthesis. Macrolides(Bs) Azithromycin Zithromax, Sumamed, Xithrone Streptococcal infections...
30 KB (747 words) - 08:06, 6 January 2024