• Thumbnail for Malonyl-CoA decarboxylase
    Malonyl-CoA decarboxylase (EC 4.1.1.9), (which can also be called MCD and malonyl-CoA carboxyl-lyase) is found in bacteria and humans and has important...
    15 KB (1,922 words) - 14:51, 26 August 2023
  • Thumbnail for Malonyl-CoA
    acid+CoA+ATP\ {\xrightarrow[{ACSF3}]{Malonyl{-}CoA\ Synthetase}}\ Malonyl{-}CoA\ {\xrightarrow[{MLYCD}]{Malonyl-CoA\ Decarboxylase}}\ Acetyl{-}CoA} } MCAT...
    6 KB (574 words) - 09:54, 7 March 2024
  • Thumbnail for Malonic aciduria
    Malonic aciduria or malonyl-CoA decarboxylase deficiency (MCD) is an autosomal-recessive metabolic disorder caused by a genetic mutation that disrupts...
    15 KB (1,717 words) - 19:44, 16 May 2024
  • Thumbnail for Acetyl-CoA carboxylase
    Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme (EC 6.4.1.2) that catalyzes the irreversible carboxylation of acetyl-CoA to produce malonyl-CoA through...
    27 KB (2,990 words) - 21:27, 4 July 2024
  • malonyl-CoA depends on the balance between acetyl-CoA carboxylase (ACC) and malonyl-CoA decarboxylase (MCD). AMP-activated protein kinase (AMPK) is reported...
    12 KB (1,520 words) - 20:36, 31 August 2024
  • Thumbnail for Acetyl-CoA
    articles. The pathway can be downloaded and edited at WikiPathways. Malonyl-CoA decarboxylase Dawson RM, Elliott DC, Elliott WH, Jones KM (2002). Data for Biochemical...
    22 KB (2,097 words) - 03:05, 2 November 2024
  • Thumbnail for Ketogenesis
    promotes fatty acid oxidation, switches off acetyl-CoA carboxylase, turns on malonyl-CoA decarboxylase, and consequently induces ketogenesis. Ethanol is...
    19 KB (2,337 words) - 16:33, 17 August 2024
  • may refer to: Magnetic circular dichroism, with polarized light Malonyl-CoA decarboxylase, an enzyme involved in fatty acid biosynthesis Mesoscale convective...
    2 KB (245 words) - 23:26, 3 October 2024
  • Kim, YS (15 October 1998). "A gene cluster encoding malonyl-CoA decarboxylase (MatA), malonyl-CoA synthetase (MatB) and a putative dicarboxylate carrier...
    6 KB (519 words) - 22:42, 2 January 2024
  • Thumbnail for MCAT (gene)
    Malonyl CoA-acyl carrier protein transacylase, mitochondrial is an enzyme that in humans is encoded by the MCAT gene. The protein encoded by this gene...
    5 KB (702 words) - 11:39, 4 March 2023
  • ventricular tachycardia Mallory–Weiss syndrome Malonic aciduria Malonyl-CoA decarboxylase deficiency Malouf syndrome Malpuech facial clefting syndrome Mandibuloacral...
    28 KB (2,469 words) - 04:35, 13 June 2024
  • Thumbnail for Inborn error of lipid metabolism
    - 3-hydroxy-3-methylglutaryl-CoA lyase Malonyl-CoA decarboxylase deficiency - Malonyl-CoA decarboxylase Primary carnitine deficiency - SLC22A5 (carnitine...
    4 KB (356 words) - 19:39, 30 October 2024
  • currently in phase 1/2, is worth mentioning. In 1984, CMAMMA due to malonyl-CoA decarboxylase deficiency was described for the first time in a scientific study...
    31 KB (3,256 words) - 19:45, 30 October 2024
  • Thumbnail for Methylmalonic acidemias
    M, et al. (February 2006). "Brain abnormalities in a case of malonyl-CoA decarboxylase deficiency". Molecular Genetics and Metabolism. 87 (2): 102–106...
    48 KB (4,435 words) - 15:54, 30 October 2024
  • Long-chain hydroxyacyl-CoA dehydrogenase deficiency Malabsorption Malaria (malignant tertian) Maldigestion Malonyl-CoA decarboxylase deficiency Maple syrup...
    21 KB (1,265 words) - 01:46, 22 December 2023
  • acetate + malonyl-CoA Thus, the two substrates of this enzyme are acetyl-CoA and malonate, whereas its two products are acetate and malonyl-CoA. This enzyme...
    2 KB (143 words) - 18:36, 23 January 2024
  • Thumbnail for AMP-activated protein kinase
    oxidation. It is also thought that the decrease in malonyl-CoA occurs as a result of malonyl-CoA decarboxylase (MCD), which may be regulated by AMPK. MCD is...
    65 KB (7,149 words) - 14:04, 13 November 2024
  • Thumbnail for Coenzyme A
    Coenzyme A (redirect from CoA-SH)
    phosphopantothenoylcysteine decarboxylase (PPC-DC; CoaC) 4′-phosphopantetheine is adenylated (or more properly, AMPylated) to form dephospho-CoA by the enzyme phosphopantetheine...
    26 KB (2,528 words) - 21:25, 28 August 2024
  • fatty acid synthesis (mtFASII), in which malonyl-CoA is formed from malonic acid with the help of malonyl-CoA synthetase (ACSF3), which then becomes the...
    41 KB (4,751 words) - 20:26, 4 September 2024
  • formed into malonyl-CoA by acetyl-CoA carboxylase, at which point malonyl-CoA is destined to feed into the fatty acid synthesis pathway. Acetyl-CoA carboxylase...
    50 KB (5,561 words) - 07:03, 13 August 2024
  • Thumbnail for Sirtuin 4
    insulin secretion in response to amino acids. A deacetylation of malonyl-CoA decarboxylase enzyme by SIRT4 represses the enzyme activity, inhibiting fatty...
    7 KB (853 words) - 01:11, 4 March 2023
  • transformations. Biotin-coupled processes effect the decarboxylation of malonyl-CoA to acetyl-CoA. Thiamine (T:) is the active component for decarboxylation of...
    12 KB (1,289 words) - 20:44, 17 November 2024
  • acetyl-[acyl-carrier protein] + malonate ⇌ {\displaystyle \rightleftharpoons } malonyl-[acyl-carrier protein] + acetate This is the first step in the catalysis...
    3 KB (311 words) - 12:55, 26 August 2023
  • decarboxylase EC 4.1.1.7: benzoylformate decarboxylase EC 4.1.1.8: oxalyl-CoA decarboxylase EC 4.1.1.9: malonyl-CoA decarboxylase EC 4.1.1.10: Now included with...
    62 KB (7,931 words) - 19:04, 4 January 2024
  • loading module contains a ketosynthase‐like decarboxylase domain (KSQ) that decarboxylates the methylmalonyl-CoA loaded onto the ACP via the AT. This results...
    13 KB (1,599 words) - 21:14, 28 August 2024
  • infertility, nonsyndromic, autosomal recessive; 612997; CATSPER1 Malonyl-CoA decarboxylase deficiency; 248360; MLYCD Mandibuloacral dysplasia with type B...
    234 KB (18,877 words) - 06:16, 6 November 2024
  • Thumbnail for Naringenin
    Naringenin (category Histidine decarboxylase inhibitors)
    of the liver enzyme naringinase. Naringenin is derived from malonyl-CoA and 4-coumaroyl-CoA. The latter is derived from phenylalanine. The resulting tetraketide...
    13 KB (1,229 words) - 20:23, 4 October 2024
  • Thumbnail for Β-Alanine
    malonate-semialdehyde dehydrogenase. Malonate is then converted into malonyl-CoA and enter fatty acid biosynthesis. Alternatively, β-alanine can be diverted...
    13 KB (1,351 words) - 02:58, 8 October 2024
  • Thumbnail for Chromosome 22
    intergenic non-protein coding RNA 899 MAPK1 MAPK12 MCAT: encoding enzyme malonyl CoA-acyl carrier protein transacylase, mitochondrial MCM5 MIF MIRLET7BHG:...
    27 KB (2,209 words) - 17:18, 18 August 2024
  • dehydrogenase EC 1.2.1.74: abieta-7,13-dien-18-al dehydrogenase EC 1.2.1.75: malonyl CoA reductase (malonate semialdehyde-forming) EC 1.2.1.76: succinate-semialdehyde...
    189 KB (24,607 words) - 12:36, 11 June 2024