• In cell biology, microtubule nucleation is the event that initiates de novo formation of microtubules (MTs). These filaments of the cytoskeleton typically...
    13 KB (1,601 words) - 07:11, 22 February 2024
  • Thumbnail for Microtubule
    for the nucleation of microtubules. Because nucleation from the centrosome is inherently symmetrical, Golgi-associated microtubule nucleation may allow...
    64 KB (7,838 words) - 19:01, 10 September 2024
  • the chromosomes during cell division. The MTOC is a major site of microtubule nucleation and can be visualized in cells by immunohistochemical detection...
    9 KB (1,113 words) - 23:36, 11 December 2023
  • Thumbnail for Spindle apparatus
    chromosomes. In an alternative self assembly model, microtubules undergo acentrosomal nucleation among the condensed chromosomes. Constrained by cellular...
    28 KB (3,300 words) - 12:32, 30 September 2024
  • Thumbnail for Centrosome
    pericentriolar material (PCM). The PCM contains proteins responsible for microtubule nucleation and anchoring — including γ-tubulin, pericentrin and ninein. In...
    24 KB (2,611 words) - 13:50, 13 September 2024
  • Thumbnail for Nucleation
    with nucleation. Energy consuming self-organising systems such as the microtubules in cells also show nucleation and growth. Heterogeneous nucleation, nucleation...
    26 KB (3,197 words) - 10:22, 30 September 2024
  • Thumbnail for CAMSAP2
    microtubules can be called "microtubule nucleation". The process occurs spontaneously via soluble αβ-tubulin dimers. Microtubule nucleation normally requires overcoming...
    22 KB (2,395 words) - 07:22, 18 August 2024
  • Thumbnail for Preprophase
    the preprophase band, a dense microtubule ring underneath the plasma membrane. The initiation of microtubule nucleation at the nuclear envelope. Plant...
    7 KB (808 words) - 15:42, 3 December 2023
  • Thumbnail for TPX2
    for microtubule branching nucleation as well. While α5-7 domains are important in this process, none of them have intrinsic microtubule nucleation activity...
    38 KB (4,947 words) - 02:30, 29 November 2023
  • Thumbnail for Tubulin
    spindle pole bodies, since these are the areas of most abundant microtubule nucleation. In these organelles, several γ-tubulin and other protein molecules...
    32 KB (3,393 words) - 05:32, 15 June 2024
  • Thumbnail for TUBGCP4
    gene. It is part of the gamma tubulin complex, which required for microtubule nucleation at the centrosome. Tubulin TUBGCP2 TUBGCP3 TUBGCP5 TUBGCP6 GRCh38:...
    2 KB (340 words) - 02:07, 4 March 2023
  • Thumbnail for Pericentriolar material
    surrounds the two centrioles. The PCM contains proteins responsible for microtubule nucleation and anchoring including γ-tubulin, pericentrin and ninein. Although...
    3 KB (341 words) - 17:13, 12 February 2023
  • Thumbnail for Meiosis
    formed, generating a barrel shaped spindle. In human oocytes spindle microtubule nucleation begins on the chromosomes, forming an aster that eventually expands...
    64 KB (7,478 words) - 23:27, 22 August 2024
  • required for microtubule nucleation. Spc98p, Spc97p and Tub4p are found at the inner and outer plaques of SPB and are involved in microtubules organization...
    7 KB (1,004 words) - 16:27, 19 December 2022
  • Thumbnail for Centrosome cycle
    pericentriolar material (PCM). The PCM is essential for nucleation and organization of microtubules. The centrosome cycle is important to ensure that daughter...
    18 KB (2,151 words) - 13:47, 13 September 2024
  • Thumbnail for TUBGCP3
    gene. It is part of the gamma tubulin complex, which required for microtubule nucleation at the centrosome. Tubulin TUBGCP2 TUBGCP4 TUBGCP5 TUBGCP6 ENSG00000126216...
    3 KB (425 words) - 01:33, 4 March 2023
  • Thumbnail for Aster (cell biology)
    EB1 and adenomatous polyposis coli (APC). Growth of Microtubules Asters grow through nucleation and polymerization. At the negative ends of the aster...
    5 KB (631 words) - 23:27, 14 November 2024
  • Thumbnail for TUBGCP5
    gene. It is part of the gamma tubulin complex, which required for microtubule nucleation at the centrosome. Tubulin TUBGCP2 TUBGCP3 TUBGCP4 TUBGCP6 ENSG00000275835...
    3 KB (449 words) - 02:07, 4 March 2023
  • Thumbnail for TUBG1
    it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required...
    4 KB (515 words) - 05:08, 17 June 2024
  • Thumbnail for TUBGCP2
    It is part of the gamma-tubulin complex, which is required for microtubule nucleation at the centrosome. Tubulin TUBGCP3 TUBGCP4 TUBGCP5 TUBGCP6 GRCh38:...
    6 KB (552 words) - 02:27, 28 November 2023
  • Thumbnail for TUBGCP6
    gene. It is part of the gamma tubulin complex, which required for microtubule nucleation at the centrosome. Tubulin TUBGCP2 TUBGCP3 TUBGCP4 TUBGCP5 GRCh38:...
    3 KB (407 words) - 00:18, 5 October 2022
  • cells. This leads to the basic assumption that +TIPs may aid in microtubule nucleation and anchoring; however, its distinct role at centrosomes still awaits...
    8 KB (875 words) - 07:52, 27 May 2024
  • Thumbnail for NEDD1
    causes impaired centrosome and chromatin microtubules assembly that results in the failure of microtubule nucleation and prevents proper spindle formation...
    4 KB (518 words) - 16:17, 6 April 2024
  • Thumbnail for MECP2
    of G2/M transition of mitotic cell cycle positive regulation of microtubule nucleation transcription initiation from RNA polymerase II promoter negative...
    28 KB (3,589 words) - 18:56, 15 September 2024
  • a delayed activation of the cyclin B/CDK1 complex. Coupling of microtubule nucleation in the centrosome with mitotic events in the nucleus was lost in...
    14 KB (1,753 words) - 03:43, 26 August 2024
  • Thumbnail for Basal body
    modified centriole. The basal body serves as a nucleation site for the growth of the axoneme microtubules. Centrioles, from which basal bodies are derived...
    12 KB (1,204 words) - 14:44, 23 August 2023
  • Thumbnail for AKAP9
    Serves As a Docking Platform for Protein Kinase A Signaling and Microtubule Nucleation in Migrating T-Cells". Front. Immunol. 9 (397): 397. doi:10.3389/fimmu...
    10 KB (1,213 words) - 02:51, 19 December 2023
  • ISBN 978-0-387-74020-1. PMID 17977464. Schmit (2002). Acentrosomal microtubule nucleation in higher plants. International Review of Cytology. Vol. 220. pp...
    279 KB (31,753 words) - 16:09, 13 September 2024
  • Thumbnail for CEP192
    which gamma tubulin ring complexes and other proteins involved in microtubule nucleation and spindle assembly become functional during mitosis. GRCh38: Ensembl...
    7 KB (882 words) - 23:01, 25 March 2024
  • Thumbnail for PCNT
    spindle formation. The protein controls the nucleation of microtubules by interacting with the microtubule nucleation component γ-tubulin, thus anchoring the...
    17 KB (1,966 words) - 12:04, 8 April 2024