family members include MyoD1, Myf5, myogenin, and MRF4 (Myf6). In non-vertebrate animals, a single MyoD protein is typically found. MyoD is one of the earliest...

has shown that MyoD directly activates its own gene; this means that the protein made binds the myoD gene and continues a cycle of MyoD protein production...

cancer. MyoD can also bind to noncanonical E boxes of MyoG and regulate its expression. MyoG belongs to the MyoD transcription factor family. MyoG-E-Box...

forms normally. As no muscle is formed in Myf5;Myod double mutant zebrafish, Myf5 cooperates with Myod to promote myogenesis. The regulation of Myf5 is...

myogenesis and repair. Myogenin is a member of the MyoD family of transcription factors, which also includes MyoD, Myf5, and MRF4. In mice, myogenin is essential...

being used for ubiquitylation, rather than a lysine residue, in the protein MyoD and has been observed since in 22 other proteins in multiple species, including...

deacetylase 2 Insulin JARID1A Large tumor antigen LIN9 MCM7 MORF4L1 MRFAP1, MyoD NCOA6 PA2G4 Peroxisome proliferator-activated receptor gamma PIK3R3 Plasminogen...

in the myoD and atrogin-1 of denervated muscles, these expressions being related to muscle growth and atrophy, respectively. The increase in myoD levels...

biochemistry, medicine, and related sciences, inositol generally refers to myo-inositol (formerly meso-inositol), the most important stereoisomer of the...

work of Harold Weintraub on the role of myoblast determination protein 1 (MyoD) in reprogramming cell fate to a muscle lineage as an important precursor...

morphological and biochemical differentiation by inhibiting the expression of MyoD and myogenin, key master genes of muscle development. A role for IFRD1 in...

but, once expressed, require no additional activation – GATA, HNF, PIT-1, MyoD, Myf5, Hox, Winged Helix II.B signal-dependent – requires external signal...

helix-loop-helix (bHLH) transcription factors that regulate myogenesis: MyoD, Myf5, myogenin, and MRF4. These proteins contain a conserved basic DNA binding...

increased expression of myogenic basic helix-loop-helix transcription factors MyoD, myogenin, and MRF4 – all responsible for the induction of myocyte-specific...

2021. Patapoutian, Ardem (1996). The Role of the MyoD Family Genes During Mouse Development (Ph.D. thesis). California Institute of Technology. OCLC 35966904...

MyoD family inhibitor domain containing is a protein that in humans is encoded by the MDFIC gene. This gene product is a member of a family of proteins...

Conti F, Buanne P, Canu N, Caruso M, et al. (March 2005). "PC4 coactivates MyoD by relieving the histone deacetylase 4-mediated inhibition of myocyte enhancer...

characterization of "myoD", the first master regulatory gene. When expressed, the myoD gene produces a protein referred to as MyoD (or MyoD1), which can bind...

HNF1A, HNRPU, ING4, ING5, IRF2, LEF1, MAF, MAML1, MEF2C, MEF2D, MYBL2, Mdm2, MyoD, MEF2A, NCOA6, NFATC2, NPAS2, P53, PAX6, PCNA, PROX1, PTMA, PPARA, PPARG...

(H3K9me2) at promoter sites of target genes of MyoD. G9a also methylates MyoD, which inhibits MyoD's transcriptional activity. BHLHE41 and BHLHE40 are...

anti c-MYC hybridoma 9e 10 Nobel Prize winner Sir John Gurdon deposited MyoD clone D7F2 Nobel Prize winner Eric F. Wieschaus deposited 7 hybridomas National...

proteins HMG-N2/HMG17 and HMG-I(Y), the transcriptional activators p53, MyoD, E2F(1-3), and HIV Tat, and the general transcription factors TFIIE and TFIIF...

interact with: CDC37, CDKN1B, CDKN2B, CDKN2C, CEBPA, CCND1, CCND3, DBNL, MyoD, P16, PCNA, and SERTAD1. GRCh38: Ensembl release 89: ENSG00000135446 – Ensembl...

Differentiation is regulated by myogenic regulatory factors, including MyoD, Myf5, myogenin, and MRF4. GATA4 and GATA6 also play a role in myocyte differentiation...

and GSK3 interaction. During myogenesis, Wnt uses PA and CREB to activate MyoD and Myf5 genes. Wnt also acts in conjunction with Ryk and Src to allow for...

expression of MyoD. However, in the absence of the parallel pathway, Pitx2 can continue activating MyoD genes. The expression of Pitx2 saves MyoD gene expression...

PMID 10781029. Maleki SJ, Royer CA, Hurlburt BK (June 1997). "MyoD-E12 heterodimers and MyoD-MyoD homodimers are equally stable". Biochemistry. 36 (22): 6762–6767...

or indirectly) maintains the activity of that gene. For example, Hnf4 and MyoD enhance the transcription of many liver-specific and muscle-specific genes...

Sertoli cells, SOX9 directly targets the Amh gene as well as the prostaglandin D synthase (Ptgds) gene. SOX9 binding to the enhancer near the Amh promoter...

MyoD family inhibitor is a protein that in humans is encoded by the MDFI gene. This protein is a transcription factor that negatively regulates other myogenic...