N-myc proto-oncogene protein also known as N-Myc or basic helix-loop-helix protein 37 (bHLHe37), is a protein that in humans is encoded by the MYCN gene...
16 KB (1,978 words) - 23:41, 12 June 2024
of three related human genes: c-myc (MYC), l-myc (MYCL), and n-myc (MYCN). c-myc (also sometimes referred to as MYC) was the first gene to be discovered...
57 KB (6,717 words) - 23:11, 17 August 2024
N-myc-interactor also known as N-myc and STAT interactor is a protein that in humans is encoded by the NMI gene. NMYC interactor (NMI) interacts with NMYC...
9 KB (1,163 words) - 19:47, 3 March 2023
MYC proto-oncogene, bHLH transcription factor is a protein that in humans is encoded by the MYC gene which is a member of the Myc family of transcription...
9 KB (1,136 words) - 15:25, 2 August 2024
N-myc amplification is an independent determinant in predicting a poor outcome in childhood neuroblastoma. Those children with amplification of N-myc...
28 KB (3,173 words) - 16:31, 16 August 2024
A myc tag is a polypeptide protein tag derived from the c-myc gene product that can be added to a protein using recombinant DNA technology. It can be...
2 KB (296 words) - 22:15, 4 April 2024
appearance, and genetic features including DNA ploidy and N-myc oncogene amplification (N-myc regulates microRNAs), into low, intermediate, and high risk...
68 KB (7,168 words) - 05:06, 25 July 2024
The N-myc internal ribosome entry site (IRES) is an RNA element found in the n-myc gene. The myc family of genes when expressed are known to be involved...
2 KB (132 words) - 22:55, 18 August 2023
members of the Klf family (Klf1, Klf2, Klf4, and Klf5), the Myc family (c-myc, L-myc, and N-myc), Nanog, and LIN28, have been identified to increase the...
92 KB (10,498 words) - 20:42, 17 August 2024
OMS tend to be more mature, showing favorable histology and absence of n-myc oncogene amplification than similar tumors in children without symptoms...
21 KB (2,281 words) - 03:18, 12 June 2024
Owen Witte (redirect from Owen N. Witte)
the human prostate stem cell population and determined that the protein N-Myc, which is produced by the gene MYCN, leads to the development of aggressive...
11 KB (1,133 words) - 15:53, 1 March 2024
protein product of Max has been shown to interact with: Myc, MNT, MSH2, MXD1, MXI1, MYCL1, N-Myc, SPAG9, TEAD1, and Transformation/transcription domain-associated...
19 KB (2,166 words) - 05:43, 5 August 2024
WT1 is transcription factor that has four C-terminal zinc fingers and an N-terminal Pro/Glu-rich region and primarily functions as an activator. Mutation...
39 KB (4,855 words) - 12:42, 9 August 2024
and the Histone Deacetylase Inhibitor Panobinostat Synergistically Reduce N-Myc Expression and Induce Anticancer Effects". Clinical Cancer Research. 22...
26 KB (2,974 words) - 05:26, 31 May 2024
structure, where the two alpha helices are connected by a short loop region. The N-terminal two helices of the homeodomain are antiparallel and the longer C-terminal...
41 KB (4,385 words) - 07:06, 25 July 2024
c-Myc expression are unlikely to preserve the cells' "stemness". However, N-myc and L-myc have been identified to induce iPS cells instead of c-myc with...
73 KB (8,680 words) - 00:23, 26 April 2024
2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2 Twist Group B FIGLA Myc c-Myc l-Myc n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF...
17 KB (1,999 words) - 10:03, 27 December 2023
2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2 Twist Group B FIGLA Myc c-Myc l-Myc n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF...
8 KB (874 words) - 23:04, 18 August 2023
that in humans is encoded by the NDRG1 gene. This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily...
18 KB (2,179 words) - 12:59, 23 December 2023
2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2 Twist Group B FIGLA Myc c-Myc l-Myc n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF...
19 KB (2,243 words) - 08:04, 13 April 2024
C-terminal ligand-binding region, a core DNA-binding domain (DBD) and an N-terminal domain that contains the AF1(activation function 1) region. The core...
26 KB (2,672 words) - 14:14, 22 July 2024
hormone response elements). The DNA consensus sequence is AGGTCANAGGTCA, with N being any nucleotide. In general, this sequence occurs in the promoter region...
17 KB (1,854 words) - 04:22, 19 August 2024
development. First, Foxp3 represses expression of HER2, Skp2, SATB1 and MYC oncogenes and induces expression of tumour suppressor genes P21 and LATS2...
28 KB (3,448 words) - 17:10, 16 April 2024
will get and when it can divide into two daughter cells. One example is the Myc oncogene, which has important roles in cell growth and apoptosis. Transcription...
75 KB (8,057 words) - 04:44, 25 July 2024
receptors are modular in structure and contain the following domains: (A-B) N-terminal regulatory domain: Contains the activation function 1 (AF-1) whose...
74 KB (6,683 words) - 03:16, 19 August 2024
2 Paraxis TCF15 Scleraxis SLC LYL1 TAL 1 2 Twist Group B FIGLA Myc c-Myc l-Myc n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF...
12 KB (1,317 words) - 20:08, 28 August 2023
FGF-10 (fibroblast growth factor), BMP-4 (bone morphogenetic protein), N-myc (a proto-oncogene), syndecan (a proteglycan[check spelling]), tenascin (an...
3 KB (335 words) - 08:05, 9 October 2023
stress. NRF2 is a basic leucine zipper (bZip) transcription factor with a Cap “n” Collar (CNC) structure. NRF2 possesses seven highly conserved domains called...
29 KB (3,402 words) - 07:08, 20 May 2024
proneural bHLH genes like p-CaMKII, and pSer(336)NeuroD. Neurogenins MAX C-Myc, N-Myc TCF4 (Transcription Factor 4) These proteins contain two additional PAS...
14 KB (1,402 words) - 11:25, 6 August 2024