Nuclear pore complex protein Nup98-Nup96 is a protein that in humans is encoded by the NUP98 gene. Signal-mediated nuclear import and export proceed through...
12 KB (1,515 words) - 00:36, 4 March 2023
specific translocation event which causes a fusion between this gene and the NUP98 gene has been associated with myeloid leukemogenesis. As HOXA9 dysfunction...
26 KB (3,172 words) - 15:28, 13 May 2024
by the mitotiv kinase NIMA. NIMA potentially phosphorylates nucleoporins Nup98 and Gle2/Rae1, leading to NPC remodeling. This remodeling allows the nuclear...
27 KB (3,152 words) - 03:37, 19 August 2024
involved in ribosome assembly. Fusion of this gene and the nucleoporin gene, NUP98, by inversion 11 (p15q22) chromosome translocation is found in the patients...
5 KB (695 words) - 05:28, 28 March 2024
still be mediated by Nup98, a soluble Nup protein that shuttles between the nucleoplasm and NPC at the nuclear membrane. Nup98 seems to be responsible...
12 KB (1,588 words) - 11:37, 28 July 2024
neoplasms and precancerous dysplasias. NUP88 has been shown to interact with NUP98. GRCh38: Ensembl release 89: ENSG00000108559 – Ensembl, May 2017 GRCm38:...
7 KB (890 words) - 21:00, 13 October 2022
membrane, others (like NUP98) act like nails with structural parts for the lining as well as parts that punch into the membrane. NUP98 was previously thought...
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Q9BW27 10946 NUP88 HGNC:8067 Q99567 10947 NUP93 HGNC:28958 Q8N1F7 10948 NUP98 HGNC:8068 P52948 10949 NUP107 HGNC:29914 P57740 10950 NUP133 HGNC:18016...
282 KB (17 words) - 18:42, 6 October 2024
protein have been found for this gene. RAE1 has been shown to interact with NUP98. GRCh38: Ensembl release 89: ENSG00000101146 – Ensembl, May 2017 GRCm38:...
8 KB (1,058 words) - 10:52, 17 October 2022
encoded by the TNPO2 gene. TNPO2 has been shown to interact with NXF1, NUP98 and Ran (biology). GRCh38: Ensembl release 89: ENSG00000105576 – Ensembl...
4 KB (527 words) - 01:51, 17 April 2022
complex: Nucleoporin NUP35 NUP37 NUP43 NUP50 NUP54 NUP62 NUP85 NUP88 NUP93 NUP98 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214 AAAS Nucleolus...
9 KB (1,123 words) - 08:02, 18 May 2024
NUP85 Nucleoporin 85 NUP88 NUP88 Nucleoporin 88 NUP98 NUP98/NUP96 Nuclear pore complex protein Nup98-Nup96 OASL OASL/OASL1 2'-5'-Oligoadenylate Synthetase...
183 KB (12,460 words) - 13:46, 23 September 2024
Billström R, Strömbeck B, Mitelman F, Johansson B (Jan 2003). "Fusion of the NUP98 gene and the homeobox gene HOXC13 in acute myeloid leukemia with t(11;12)(p15;q13)"...
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PMC 20743. PMID 9114010. Zolotukhin AS, Felber BK (1999). "Nucleoporins nup98 and nup214 participate in nuclear export of human immunodeficiency virus...
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inhibiting mRNA nuclear export through direct interaction with the host RAE1-NUP98 complex. This inhibits interferon signaling and thus establishment of antiviral...
3 KB (358 words) - 16:10, 6 January 2022
Jason H. (2013-03-26). Misteli, Tom (ed.). "A Conserved Role for Human Nup98 in Altering Chromatin Structure and Promoting Epigenetic Transcriptional...
8 KB (869 words) - 15:10, 14 January 2024
PMID 10811825. Fontoura BM, Blobel G, Yaseen NR (October 2000). "The nucleoporin Nup98 is a site for GDP/GTP exchange on ran and termination of karyopherin beta...
11 KB (1,280 words) - 01:56, 11 April 2024
FGFR1OP2, ZMYM2, CUTL1, SQSTM1, RANBP2, LRRFIP1, CNTRL, FGFR1OP, BCR, NUP98, MYST3, and CEP110. As detailed in FGFR1 Hematological cancers, patients...
48 KB (5,760 words) - 23:15, 2 December 2023
transporter also interacts with p62. P62 also interacts with Nup93, and when Nup98 is depleted p62 fails to assemble with nuclear pore complexes. Mutant pores...
18 KB (2,260 words) - 06:28, 2 December 2022
karyopherins. In SARS-CoV-2, the ORF6 protein reportedly interacts with RAE1 and NUP98, blocking karyopherin interactions. Liu DX, Fung TS, Chong KK, Shukla A...
6 KB (619 words) - 13:20, 18 February 2024
2002). "Single-translocation and double-chimeric transcripts: detection of NUP98-HOXA9 in myeloid leukemias with HOXA11 or HOXA13 breaks of the chromosomal...
9 KB (972 words) - 03:23, 12 August 2024
Karyopherin alpha 2, Mothers against decapentaplegic homolog 3, NUP153 NUP50, NUP98, Nucleoporin 62, P53, Parathyroid hormone-related protein, RANBP1, RANBP2...
17 KB (1,942 words) - 15:53, 3 April 2024
interact with a number of other proteins including SSSCA1, TSSC1, GAPDH, NUP98 and SNAI1. FLJ25737 mRNA sequences perfectly match with two regions on the...
8 KB (698 words) - 00:08, 24 September 2024
t(8;9)(p11;q33) FGFR1OP 6q27 t(6;8)(q27;p11) BCR 22q11 t(8;22)(p11;q11 NUP98 11p15 t(8;11)(p11-p15) MYST3 8p11.21 multiple CEP110 16p12 t(8;16)(p11;p12)...
44 KB (5,003 words) - 12:45, 26 September 2024
PMID 9373149. Nakamura T, Yamazaki Y, Hatano Y, Miura I (1999). "NUP98 is fused to PMX1 homeobox gene in human acute myelogenous leukemia with...
10 KB (1,265 words) - 19:31, 13 June 2022
RK (2004). "Differential and Common Leukemogenic Potentials of Multiple NUP98-Hox Fusion Proteins Alone or with Meis1". Mol. Cell. Biol. 24 (5): 1907–17...
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PMC 110274. PMID 9765402. Zolotukhin AS, Felber BK (Jan 1999). "Nucleoporins nup98 and nup214 participate in nuclear export of human immunodeficiency virus...
12 KB (1,611 words) - 03:00, 28 March 2022
(March 2004). "Differential and common leukemogenic potentials of multiple NUP98-Hox fusion proteins alone or with Meis1". Molecular and Cellular Biology...
9 KB (1,089 words) - 06:56, 7 August 2024
6581. PMID 11549311. Rosati R, La Starza R, Veronese A, et al. (2002). "NUP98 is fused to the NSD3 gene in acute myeloid leukemia associated with t(8;11)(p11...
5 KB (633 words) - 23:03, 18 August 2023
2002). "Single-translocation and double-chimeric transcripts: detection of NUP98-HOXA9 in myeloid leukemias with HOXA11 or HOXA13 breaks of the chromosomal...
7 KB (863 words) - 16:38, 22 August 2024