Neprilysin (/ˌnɛprɪˈlaɪsɪn/; also known as membrane metallo-endopeptidase (MME), neutral endopeptidase (NEP), cluster of differentiation 10 (CD10) and...

fixed-dose combination medication for use in heart failure. It consists of the neprilysin inhibitor sacubitril and the angiotensin receptor blocker valsartan. The...

(LBQ657) by de-ethylation via esterases. Sacubitrilat inhibits the enzyme neprilysin, which is responsible for the degradation of atrial and brain natriuretic...

(ACE) inhibitors, angiotensin II antagonists (ARBs), and Angiotensin-Neprilysin Inhibitor LCZ969.: 120  The angioedema appears to be dose dependent as...

nesiritide in patients with acute decompensated heart failure. Blockade of neprilysin, a protease known to degrade members of the natriuretic peptide family...

at pH 2. Glutamyl endopeptidase - cuts after Glu. Works best at pH 8. Neprilysin "endopeptidase". Merriam-Webster. Archived from the original on 21 December...

experimental antihypertensive agent that was never marketed. It inhibits both neprilysin (neutral endopeptidase, NEP) and angiotensin-converting enzyme (ACE)....

different kininases: angiotensin-converting enzyme (ACE, kininase II), neprilysin, NEP2, aminopeptidase P (APP), carboxypeptidase N (CPN, kininase I), Carboxypeptidase...

Natriuretic peptides will lose their activity when degraded by the enzyme neprilysin which is found on the plasma membrane. The existence of natriuretic peptides...

Engineering (MME) Membrane metallo-endopeptidase, an enzyme also named neprilysin Michigan Merit Exam, a minimum-competency test for students Mitsubishi...

Petersburg, Russia, est. 1988 Nepal, FIFA and IOC code NEP Nepr, a Norse god Neprilysin, or neutral endopeptidase Needle exchange programme Net ecosystem production...

buffalo, Bubalus arnee Lake Arni or Arnisee ARNI, angiotensin receptor-neprilysin inhibitor: Valsartan/sacubitril Arani (disambiguation) Arny (disambiguation)...

protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases. There are several alleles of the...

endocytosis by astrocytes and microglial cells, (2) enzymatic degradation by neprilysin or insulysin (3) cleared by way of the blood–brain barrier or (4) drained...

urodilatin, and adrenomedullin. Neutral endopeptidase (NEP) also known as neprilysin is the enzyme that metabolizes natriuretic peptides. Several inhibitors...

inhibitors, angiotensin II receptor blockers (ARBs), or angiotensin receptor-neprilysin inhibitors, along with beta blockers, mineralocorticoid receptor antagonists...

Gong J, Lefkowitz MP, Rizkala AR, et al. (September 2014). "Angiotensin-neprilysin inhibition versus enalapril in heart failure". The New England Journal...

The polypeptide Ang I can be converted into Ang (1-7) by the actions of neprilysin (NEP) and thimet oligopeptidase (TOP) enzymes. Also, Ang II can be hydrolyzed...

valine or threonine and forms part of the S1' subsite in thermolysin and neprilysin, 'b' is an uncharged residue, and 'c' a hydrophobic residue. Proline is...

fibrillation instead of warfarin PARADIGM-HF (2014) — use of angiotensin-neprilysin inhibitor in heart failure ISCHEMIA (2020) — medical therapy is as good...

valine or threonine and forms part of the S1' subsite in thermolysin and neprilysin, 'b' is an uncharged residue, and 'c' a hydrophobic residue. Proline is...

activate or inactivate oligopeptide (pro)-hormones such as opioid peptides, neprilysin is another member of this group, in the case of the metallopeptidases...

examples of endopeptidase inhibitors include the following: Neprilysin inhibitors Selective neprilysin inhibitors Candoxatril - prodrug to candoxatrilat Candoxatrilat...

enhance the activity of major amyloid-beta peptide degrading enzymes like neprilysin in the brain resulting in a slower development of Alzheimer's disease...

active prodrug of candoxatrilat (UK-73967). Human neutral endopeptidase (neprilysin) as the neutral endopeptidase 24.11 complexed (RB-101) with phosphoramidon...

label Common acute lymphoblastic leukemia antigen, also known as CD10 or Neprilysin Calla (film), a 1999 South Korean film by Song Hae-sung The Cognitive...

Lymphoma Neprilysin Lymphosarcoma CD3 CD79a...

inhibits both angiotensin-converting enzyme (ACE) and neutral endopeptidase (neprilysin). "International Nonproprietary Names for Pharmaceutical Substances (INN)...

active in the cell. Nicastrin has also been identified as a regulator of neprilysin, an enzyme involved in the degradation of amyloid beta fragment. The protein...

Endopeptidase-2 may refer to: Neprilysin, an enzyme Meprin A, an enzyme This disambiguation page lists articles associated with the title Endopeptidase-2...