Neurosteroids, also known as neuroactive steroids, are endogenous or exogenous steroids that rapidly alter neuronal excitability through interaction with...
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This is a list of neurosteroids, or natural and synthetic steroids that are active on the mammalian nervous system through receptors other than steroid...
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Dehydroepiandrosterone (category Neurosteroids)
binding to an array of nuclear and cell surface receptors, and acting as a neurosteroid and modulator of neurotrophic factor receptors. In the United States...
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brain, complicating drug discovery. For example, the binding site of neurosteroids in the GABAA receptor is not known and barbiturates bind at a beta subunit...
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Allopregnanolone (category Neurosteroids)
Allopregnanolone is a naturally occurring neurosteroid which is made in the body from the hormone progesterone. As a medication, allopregnanolone is referred...
50 KB (4,782 words) - 13:47, 19 July 2024
Pregnenolone (category Neurosteroids)
addition, pregnenolone is biologically active in its own right, acting as a neurosteroid. In addition to its role as a natural hormone, pregnenolone has been...
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Norethisterone (section Neurosteroid activity)
Norethisterone, also known as norethindrone and sold under many brand names, is a progestin medication used in birth control pills, menopausal hormone...
92 KB (9,328 words) - 04:45, 11 July 2024
3α-Androstanediol (category Neurosteroids)
hormone and neurosteroid and a metabolite of androgens like dihydrotestosterone (DHT). 3α-Androstanediol is an inhibitory androstane neurosteroid and weak...
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corticosteroids (glucocorticoids and mineralocorticoids), as well as neurosteroids, from cholesterol. Steroidogenic enzymes are most highly expressed in...
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ISBN 978-0-12-088397-4. Herd MB, Belelli D, Lambert JJ (October 2007). "Neurosteroid modulation of synaptic and extrasynaptic GABA(A) receptors". Pharmacology...
51 KB (5,494 words) - 04:45, 10 August 2024
(5α-androstane-3α,17β-diol) – an endogenous androgen, estrogen, and neurosteroid 3β-Androstanediol (5α-androstane-3β,17β-diol) – an endogenous estrogen...
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Androsterone (category Neurosteroids)
or 3α-hydroxy-5α-androstan-17-one, is an endogenous steroid hormone, neurosteroid, and putative pheromone. It is a weak androgen with a potency that is...
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Dehydroepiandrosterone sulfate (category Neurosteroids)
than DHEA. The steroid is hormonally inert and is instead an important neurosteroid and neurotrophin. Similarly to other conjugated steroids, DHEA-S is devoid...
28 KB (2,570 words) - 16:18, 29 November 2023
Testosterone (section Neurosteroid activity)
Alexaki VI, Avlonitis N, Pediaditakis I, Efstathopoulos P, et al. (2011). "Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors...
149 KB (15,717 words) - 06:34, 13 August 2024
Pregnenolone sulfate (category Neurosteroids)
Pregnenolone sulfate (PS, PREGS) is an endogenous excitatory neurosteroid that is synthesized from pregnenolone. It is known to have cognitive and memory-enhancing...
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Pregnanolone (category Neurosteroids)
Pregnanolone, also known as eltanolone, is an endogenous inhibitory neurosteroid which is produced in the body from progesterone. It is closely related...
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Androstenol (category Neurosteroids)
or 3α-androstenol), is a 16-androstene class steroidal pheromone and neurosteroid in humans and other mammals, notably pigs. It possesses a characteristic...
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Pregnenolone (medication) (category Neurosteroids)
as a naturally occurring and endogenous steroid. It is described as a neurosteroid and anti-inflammatory drug and was used in the treatment of rheumatoid...
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on GABAAR subtype-dependent extracellular domain sites. Alcohols and neurosteroids, among other general anesthetics, act at GABAAR subunit-interface transmembrane...
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Progesterone (category Neurosteroids)
corticosteroids, and plays an important role in brain function as a neurosteroid. In addition to its role as a natural hormone, progesterone is also used...
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progesterone. Progesterone also has antimineralocorticoid and inhibitory neurosteroid activity, whereas it appears to have little or no glucocorticoid or antiandrogenic...
175 KB (18,968 words) - 15:19, 3 July 2024
methaqualone binding site is distinct from the benzodiazepine, barbiturate, and neurosteroid binding sites on the GABA-A receptor complex, and it may partially overlap...
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mineralocorticoids List of neurosteroids – excitatory, inhibitory, mixed, neurotrophic, antineurotrophic, and other neurosteroids, as well as pheromones and...
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Neurosteroidogenesis inhibitor (redirect from Anti-neurosteroid)
that inhibits the production of endogenous neurosteroids. Neurosteroids include the excitatory neurosteroids pregnenolone sulfate, dehydroepiandrosterone...
13 KB (1,363 words) - 18:12, 15 July 2024
ISBN 978-1-4020-6854-6. Tvrdeić A, Poljak L (2016). "Neurosteroids, GABAA receptors and neurosteroid based drugs: are we witnessing the dawn of the new...
51 KB (4,969 words) - 08:21, 27 July 2024
Tetrahydrodeoxycorticosterone (category Neurosteroids)
also referred to as allotetrahydrocorticosterone, is an endogenous neurosteroid. It is synthesized from the adrenal hormone deoxycorticosterone by the...
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Miscellaneous Ademetionine (SAMe) GABAkine neurosteroids (brexanolone, zuranolone) Hypericum perforatum (St. John's Wort) Oxitriptan (5-HTP) Rubidium...
118 KB (11,372 words) - 12:35, 16 August 2024
pressure; and possibly improved cardiovascular health. Progesterone has neurosteroid activity via metabolism into allopregnanolone and pregnanolone, potent...
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Anabolic steroid (section Neurosteroid activity)
have been found to modulate the GABAA receptor similarly to endogenous neurosteroids like allopregnanolone, 3α-androstanediol, dehydroepiandrosterone sulfate...
209 KB (21,563 words) - 04:07, 15 August 2024
Benorterone, an antiandrogen Dehydroandrosterone Dehydroepiandrosterone, a neurosteroid 4-Dehydroepiandrosterone Epitestosterone Etiocholanedione Hexahydrocannabivarin...
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